Patrick Hank Pun, MD

Associate Professor of Medicine
Member of the Duke Clinical Research Institute
Campus mail Duke Box 17969, Durham, NC 27705
Phone (919) 668-8529

My current research interest is in understanding the mechanisms of cardiovascular disease among patients with chronic kidney disease, with a particular focus on the epidemic of sudden cardiac death. The ultimate goal is to reduce the impact of sudden death through improved risk stratification and novel risk mitigation therapies. Current investigations are focused on identifying novel genetic and biomarker risk factors among CKD patients, understanding the interplay of hemodialysis-specific exposures in the development of arrhythmias, and examining the risks and benefits of implantable cardioverter defibrillators among CKD patients using clinical trial and registry data.

Education and Training

  • Fellow in Nephrology, Medicine, Duke University, 2004 - 2007
  • Medical Resident, Medicine, Duke University, 2001 - 2004
  • M.D., Vanderbilt University, 2001

Publications

Hofacker, Samuel A., Laura J. Fish, Audrey L. Blewer, and Patrick H. Pun. “Barriers and Facilitators to Performing Cardiopulmonary Resuscitation During Treatment in Outpatient Hemodialysis Clinics: A Qualitative Study.” Nephrol Nurs J 47, no. 5 (September 2020): 401–11.

PMID
33107712
Scholars@Duke

Assimon, Magdalene M., Lily Wang, Patrick H. Pun, Wolfgang C. Winkelmayer, and Jennifer E. Flythe. “Use of QT Prolonging Medications by Hemodialysis Patients and Individuals Without End-Stage Kidney Disease.” J Am Heart Assoc 9, no. 13 (July 7, 2020): e015969. https://doi.org/10.1161/JAHA.120.015969.

PMID
32578475
Full Text

Edmonston, Daniel L., and Patrick H. Pun. “Coronary artery disease in chronic kidney disease: highlights from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.” Kidney Int 97, no. 4 (April 2020): 642–44. https://doi.org/10.1016/j.kint.2019.12.010.

PMID
32093916
Full Text

Starks, Monique Anderson, Jingjing Wu, Eric D. Peterson, Judith A. Stafford, Roland A. Matsouaka, L Ebony Boulware, Laura P. Svetkey, Paul S. Chan, Patrick H. Pun, and Patrick H. for American Heart Association’s Get With the Guidelines-Resuscitation Investigators. “In-Hospital Cardiac Arrest Resuscitation Practices and Outcomes in Maintenance Dialysis Patients.” Clin J Am Soc Nephrol 15, no. 2 (February 7, 2020): 219–27. https://doi.org/10.2215/CJN.05070419.

PMID
31911423
Full Text

Pun, Patrick H., and Sana M. Al-Khatib. “Implantable Defibrillators for Primary Prevention of Sudden Death in Patients on Dialysis.” Am J Kidney Dis 74, no. 6 (December 2019): 857–60. https://doi.org/10.1053/j.ajkd.2019.05.002.

PMID
31257051
Full Text

Hein, Aaron M., Julia J. Scialla, Linda K. Shaw, Karen Chiswell, Patrick H. Pun, and Robert J. Mentz. “Increased eGFR Variability is Observed in Patients with HFrEF Compared to no HF or HFpEF in the Setting of Chronic Kidney Disease.” In Journal of Cardiac Failure, 25:S92–S92. Elsevier BV, 2019. https://doi.org/10.1016/j.cardfail.2019.07.263.

Full Text

Pun, Patrick H., Matthew E. Dupre, Clark Tyson, Sana M. Al-Khatib, and Christopher B. Granger. “CPR for OHCA Is Rarely Successful, and What Is "Success" Anyway? Reply.” Journal of the American Society of Nephrology 30, no. 6 (June 2019): 1137–38. https://doi.org/10.1681/ASN.2019040353.

Full Text

Pun, Patrick H., Matthew E. Dupre, Clark Tyson, Sana M. Al-Khatib, and Christopher B. Granger. “CPR for OHCA Is Rarely Successful, and What Is "Success" Anyway? Reply.” Journal of the American Society of Nephrology 30, no. 6 (June 1, 2019): 1137–38. https://doi.org/10.1681/ASN.2019040353.

Full Text

Pun, Patrick H., Matthew E. Dupre, Clark Tyson, Sana M. Al-Khatib, and Christopher B. Granger. “Authors' Reply.” Journal of the American Society of Nephrology : Jasn 30, no. 6 (June 2019): 1137–38. https://doi.org/10.1681/asn.2019040353.

PMID
31061137
Full Text

Pages