Redford B. Williams, MD

Professor of Psychiatry and Behavioral Sciences
Professor of Psychology and Neuroscience
Professor of Medicine
Campus mail 905 W. Main Street, Suite 22 (2nd Floor), Durham, NC 27701
Phone (919) 684-3863
Email address redfordw@duke.edu

My research aims to identify psychosocial factors that are involved in the pathogenesis and course of major medical disorders, to characterize the biobehavioral mechanisms whereby such factors influence disease, and to develop both behavioral and pharmacologic means of preventing or ameliorating the adverse impact of psychosocial factors on health and disease. Specific projects that are currently active include: 1) The influence of hostile personality, social isolation, depression and other psychosocial risk factors upon the development and course of cardiometabolic disease; 2) Biological and genetic mechanisms whereby psychosocial risk factors influence disease development and course; and 3) Behavioral and pharmacologic approaches to ameliorate impact of psychosocial risk factors on disease risk and course.

Education and Training

  • M.D., Yale University, 1967

Publications

Brummett, Beverly H., Michael A. Babyak, Cynthia M. Kuhn, Ilene C. Siegler, and Redford B. Williams. “A functional polymorphism in the HTR2C gene associated with stress responses: a validation study..” Biol Psychol 103 (December 2014): 317–21. https://doi.org/10.1016/j.biopsycho.2014.10.006.

PMID
25457638
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Samad, Zainab, Stephen Boyle, Mads Ersboll, Amit N. Vora, Ye Zhang, Richard C. Becker, Redford Williams, et al. “Sex differences in platelet reactivity and cardiovascular and psychological response to mental stress in patients with stable ischemic heart disease: insights from the REMIT study..” J Am Coll Cardiol 64, no. 16 (October 21, 2014): 1669–78. https://doi.org/10.1016/j.jacc.2014.04.087.

PMID
25323254
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Proeschold-Bell, R. J., R. Swift, H. E. Moore, G. Bennett, X. F. Li, R. Blouin, V. P. Williams, R. B. Williams, and D. Toole. “Corrigendum to Use of a randomized multiple baseline design: Rationale and design of the Spirited Life holistic health intervention study [Contemp Clin Trials 35 (2013) 138-152].” Contemporary Clinical Trials 37, no. 1 (January 1, 2014). https://doi.org/10.1016/j.cct.2013.09.013.

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Haberstick, Brett C., Jeffrey M. Lessem, John K. Hewitt, Andrew Smolen, Christian J. Hopfer, Carolyn T. Halpern, Ley A. Killeya-Jones, et al. “MAOA genotype, childhood maltreatment, and their interaction in the etiology of adult antisocial behaviors..” Biol Psychiatry 75, no. 1 (January 1, 2014): 25–30. https://doi.org/10.1016/j.biopsych.2013.03.028.

PMID
23726513
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Brummett, Beverly H., Michael A. Babyak, Redford B. Williams, Kathleen Mullan Harris, Rong Jiang, William E. Kraus, Abanish Singh, Paul T. Costa, Anastasia Georgiades, and Ilene C. Siegler. “A putatively functional polymorphism in the HTR2C gene is associated with depressive symptoms in white females reporting significant life stress..” Plos One 9, no. 12 (2014). https://doi.org/10.1371/journal.pone.0114451.

PMID
25514629
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Samad, Zainab, Stephen Boyle, Amit N. Vora, Richard C. Becker, Thomas L. Ortel, Cynthia Kuhn, Redford B. Williams, et al. “Sex Differences in Platelet Reactivity, Cardiovascular and Psychological Response to Mental Stress in Patients With Known Coronary Artery Disease: Data From the Responses of Mental Stress Induced Myocardial Ischemia to Escitalopram Treatment Study.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.

Scholars@Duke

Brummett, Beverly H., Michael A. Babyak, Abanish Singh, Rong Jiang, Redford B. Williams, Kathleen Mullan Harris, and Ilene C. Siegler. “Socioeconomic indices as independent correlates of C-reactive protein in the National Longitudinal Study of Adolescent Health..” Psychosom Med 75, no. 9 (November 2013): 882–93. https://doi.org/10.1097/PSY.0000000000000005.

PMID
24163384
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Boyle, Stephen H., Zainab Samad, Richard C. Becker, Redford Williams, Cynthia Kuhn, Thomas L. Ortel, Maragatha Kuchibhatla, et al. “Depressive symptoms and mental stress-induced myocardial ischemia in patients with coronary heart disease..” Psychosom Med 75, no. 9 (November 2013): 822–31. https://doi.org/10.1097/PSY.0b013e3182a893ae.

PMID
24163385
Full Text

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