Redford B. Williams, MD

Professor of Psychiatry and Behavioral Sciences
Professor of Psychology and Neuroscience
Professor of Medicine
Campus mail 905 W. Main Street, Suite 22 (2nd Floor), Durham, NC 27701
Phone (919) 684-3863
Email address redfordw@duke.edu

My research aims to identify psychosocial factors that are involved in the pathogenesis and course of major medical disorders, to characterize the biobehavioral mechanisms whereby such factors influence disease, and to develop both behavioral and pharmacologic means of preventing or ameliorating the adverse impact of psychosocial factors on health and disease. Specific projects that are currently active include: 1) The influence of hostile personality, social isolation, depression and other psychosocial risk factors upon the development and course of cardiometabolic disease; 2) Biological and genetic mechanisms whereby psychosocial risk factors influence disease development and course; and 3) Behavioral and pharmacologic approaches to ameliorate impact of psychosocial risk factors on disease risk and course.

Education and Training

  • M.D., Yale University, 1967

Publications

Lamprecht, F., R. Kvetnansky, L. K. Ng, R. B. Williams, and I. J. Kopin. “Effect of 9 -tetrahydrocannabinol on immobilization-induced changes in rat adrenal medullary enzymes..” Eur J Pharmacol 21, no. 2 (February 1973): 249–51. https://doi.org/10.1016/0014-2999(73)90235-5.

PMID
4144486
Full Text

Williams, R. B., L. K. Ng, F. Lamprecht, K. Roth, and I. J. Kopin. “9 -Tetrahydrocannabinol: a hypotensive effect in rats..” Psychopharmacologia 28, no. 3 (1973): 269–74. https://doi.org/10.1007/bf00429307.

PMID
4691001
Full Text

Ng, L. K. Y., F. Lamprecht, R. B. Williams, and I. J. Kopin. “Δ9-tetrahydrocannabinol and ethanol: Differential effects on sympathetic activity in differing environmental setting.” Science 180, no. 4093 (1973): 1368–69.

Scholars@Duke

Williams, R. B., B. Eichelman, and L. K. Ng. “Depletion of brain amines reverses blood pressure response to footshock in rat..” Nat New Biol 240, no. 104 (December 27, 1972): 276–77. https://doi.org/10.1038/newbio240276a0.

PMID
4512232
Full Text

Lamprecht, F., B. Eichelman, N. B. Thoa, R. B. Williams, and I. J. Kopin. “Rat fighting behavior: serum dopamine- -hydroxylase and hypothalamic tyrosine hydroxylase..” Science 177, no. 4055 (September 29, 1972): 1214–15. https://doi.org/10.1126/science.177.4055.1214.

PMID
4403515
Full Text

McKegney, F. P., and R. B. Williams. “Psychological aspects of hypertension. II. The differential influence of interview variables on blood pressure..” Am J Psychiatry 123, no. 12 (June 1967): 1539–45. https://doi.org/10.1176/ajp.123.12.1539.

PMID
6025189
Full Text

Williams, R. B., and F. P. McKegney. “Psychological aspects of hypertension. I. The influence of experimental interview variables on blood pressure..” Yale J Biol Med 38, no. 3 (December 1965): 265–72.

PMID
5866673
Scholars@Duke

Pages