Redford B. Williams, MD

Professor of Psychiatry and Behavioral Sciences
Professor of Psychology and Neuroscience
Professor of Medicine
Campus mail 5811 Buck Quarter Road, Hillsborough, NC 27278
Phone (919) 684-3863
Email address redfordw@duke.edu

My research aims to identify psychosocial factors that are involved in the pathogenesis and course of major medical disorders, to characterize the biobehavioral mechanisms whereby such factors influence disease, and to develop both behavioral and pharmacologic means of preventing or ameliorating the adverse impact of psychosocial factors on health and disease. Specific projects that are currently active include: 1) The influence of hostile personality, social isolation, depression and other psychosocial risk factors upon the development and course of cardiometabolic disease; 2) Biological and genetic mechanisms whereby psychosocial risk factors influence disease development and course; and 3) Behavioral and pharmacologic approaches to ameliorate impact of psychosocial risk factors on disease risk and course.

Education and Training

  • M.D., Yale University, 1967

Publications

Garson, A., R. B. Williams, and J. Reckless. “Long-term follow-up of patients with tetralogy of Fallot: physical health and psychopathology.” J Pediatr 85, no. 3 (September 1974): 429–33. https://doi.org/10.1016/s0022-3476(74)80136-8.

PMID
4853035
Full Text

Lamprecht, F., B. S. Eichelman, R. B. Williams, G. F. Wooten, and I. J. Kopin. “Serum dopamine-beta-hydroxylase (DBH) activity and blood pressure response of rat strains to shock-induced fighting.” Psychosom Med 36, no. 4 (July 1974): 298–303. https://doi.org/10.1097/00006842-197407000-00003.

PMID
4472301
Full Text

Gillin, J. C., M. S. Buchsbaum, L. S. Jacobs, D. H. Fram, R. B. Williams, T. B. Vaughan, E. Mellon, F. Snyder, and R. J. Wyatt. “Partial REM sleep deprivation, schizophrenia and field articulation.” Arch Gen Psychiatry 30, no. 5 (May 1974): 653–62. https://doi.org/10.1001/archpsyc.1974.01760110073009.

PMID
4363107
Full Text

Ng, L. K., F. Lamprecht, R. B. Williams, and I. J. Kopin. “Delta 9 -tetrahydrocannabinol and ethanol: differential effects on sympathetic activity in differing environmental setting.” Science 180, no. 4093 (June 29, 1973): 1368–69. https://doi.org/10.1126/science.180.4093.1368.

PMID
4350929
Full Text

Lamprecht, F., R. B. Williams, and I. J. Kopin. “Serum dopamine-beta-hydroxylase during development of immobilization-induced hypertension.” Endocrinology 92, no. 3 (March 1973): 953–56. https://doi.org/10.1210/endo-92-3-953.

PMID
4701493
Full Text

Eichelman, B., W. Dejong, and R. B. Williams. “Aggressive behavior in hypertensive and normotensive rat strains.” Physiol Behav 10, no. 2 (February 1973): 301–4. https://doi.org/10.1016/0031-9384(73)90314-4.

PMID
4736133
Full Text

Lamprecht, F., R. Kvetnansky, L. K. Ng, R. B. Williams, and I. J. Kopin. “Effect of 9 -tetrahydrocannabinol on immobilization-induced changes in rat adrenal medullary enzymes.” Eur J Pharmacol 21, no. 2 (February 1973): 249–51. https://doi.org/10.1016/0014-2999(73)90235-5.

PMID
4144486
Full Text

Williams, R. B., L. K. Ng, F. Lamprecht, K. Roth, and I. J. Kopin. “9 -Tetrahydrocannabinol: a hypotensive effect in rats.” Psychopharmacologia 28, no. 3 (1973): 269–74. https://doi.org/10.1007/BF00429307.

PMID
4691001
Full Text

Ng, L. K. Y., F. Lamprecht, R. B. Williams, and I. J. Kopin. “Δ9-tetrahydrocannabinol and ethanol: Differential effects on sympathetic activity in differing environmental setting.” Science 180, no. 4093 (1973): 1368–69.

Scholars@Duke

Pages