Redford B. Williams, MD

Professor of Psychiatry and Behavioral Sciences
Professor of Psychology and Neuroscience
Professor of Medicine
Campus mail 905 W. Main Street, Suite 22 (2nd Floor), Durham, NC 27701
Phone (919) 684-3863
Email address redfordw@duke.edu

My research aims to identify psychosocial factors that are involved in the pathogenesis and course of major medical disorders, to characterize the biobehavioral mechanisms whereby such factors influence disease, and to develop both behavioral and pharmacologic means of preventing or ameliorating the adverse impact of psychosocial factors on health and disease. Specific projects that are currently active include: 1) The influence of hostile personality, social isolation, depression and other psychosocial risk factors upon the development and course of cardiometabolic disease; 2) Biological and genetic mechanisms whereby psychosocial risk factors influence disease development and course; and 3) Behavioral and pharmacologic approaches to ameliorate impact of psychosocial risk factors on disease risk and course.

Education and Training

  • M.D., Yale University, 1967

Publications

Williams, Virginia P., Lauren Bishop-Fitzpatrick, James D. Lane, Lisa P. Gwyther, Edna L. Ballard, Analise P. Vendittelli, Tiffany C. Hutchins, and Redford B. Williams. “Video-based coping skills to reduce health risk and improve psychological and physical well-being in Alzheimer's disease family caregivers.” Psychosom Med 72, no. 9 (November 2010): 897–904. https://doi.org/10.1097/PSY.0b013e3181fc2d09.

PMID
20978227
Full Text

Williams, Redford B., Richard S. Surwit, Ilene C. Siegler, Allison E. Ashley-Koch, Ann L. Collins, Michael J. Helms, Anastasia Georgiades, et al. “Central nervous system serotonin and clustering of hostility, psychosocial, metabolic, and cardiovascular endophenotypes in men.” Psychosom Med 72, no. 7 (September 2010): 601–7. https://doi.org/10.1097/PSY.0b013e3181eb9d67.

PMID
20595415
Full Text

Siegler, Ilene C., Beverly H. Brummett, Redford B. Williams, Thomas L. Haney, and Peggye Dilworth-Anderson. “Caregiving, residence, race, and depressive symptoms.” Aging Ment Health 14, no. 7 (September 2010): 771–78. https://doi.org/10.1080/13607861003713257.

PMID
20635234
Full Text

Surwit, Richard S., Redford B. Williams, James D. Lane, Mark N. Feinglos, Cynthia M. Kuhn, and Anastasia Georgiades. “Plasma epinephrine predicts fasting glucose in centrally obese African-American women.” Obesity (Silver Spring) 18, no. 9 (September 2010): 1683–87. https://doi.org/10.1038/oby.2010.43.

PMID
20300086
Full Text

Siegler, Ilene C., Redford B. Williams, Barbara K. Rimer, David C. Rubin, Beverly H. Brummett, John C. Barefoot, and Paul T. Costa. “WHEN I'M 64: FINDINGS FROM THE UNC ALUMNI HEART STUDY.” International Journal of Behavioral Medicine 17 (August 1, 2010): 9–10.

Scholars@Duke

Kring, Sofia I Iqbal, Beverly H. Brummett, John Barefoot, Melanie E. Garrett, Allison E. Ashley-Koch, Stephen H. Boyle, Ilene C. Siegler, Thorkild I. A. Sørensen, and Redford B. Williams. “Impact of psychological stress on the associations between apolipoprotein E variants and metabolic traits: findings in an American sample of caregivers and controls.” Psychosom Med 72, no. 5 (June 2010): 427–33. https://doi.org/10.1097/PSY.0b013e3181de30ad.

PMID
20467002
Full Text

Brummett, Beverly H., Stephen H. Boyle, Thomas L. Ortel, Richard C. Becker, Ilene C. Siegler, and Redford B. Williams. “Associations of depressive symptoms, trait hostility, and gender with C-reactive protein and interleukin-6 response after emotion recall.” Psychosom Med 72, no. 4 (May 2010): 333–39. https://doi.org/10.1097/PSY.0b013e3181d2f104.

PMID
20190126
Full Text

Brummett, Beverly H., Stephen H. Boyle, Cynthia M. Kuhn, Ilene C. Siegler, and Redford B. Williams. “Socioeconomic status moderates associations between CNS serotonin and expression of beta2-integrins CD11b and CD11c.” J Psychiatr Res 44, no. 6 (April 2010): 373–77. https://doi.org/10.1016/j.jpsychires.2009.09.004.

PMID
19800635
Full Text

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