Richard Frothingham, MD

Associate Professor of Medicine
Assistant Professor in Molecular Genetics and Microbiology
Member of the Duke Human Vaccine Institute
Campus mail 2424 Erwin Rd, Hock Plaza Room 9089, Durham, NC 27710
Phone (919) 684-5455
Email address richard.frothingham@duke.edu

Education and Training

  • Medicine And Pediatrics Resident, Medicine, University of Rochester, 1982 - 1986
  • M.D., Duke University, 1981

Publications

Korioth-Schmitz, B, Perley, CC, Sixsmith, JD, Click, EM, Lee, S, Letvin, NL, and Frothingham, R. "Rhesus immune responses to SIV Gag expressed by recombinant BCG vectors are independent from pre-existing mycobacterial immunity." Vaccine 33, no. 42 (October 2015): 5715-5722.

PMID
26192357
Full Text

Hart, BE, Asrican, R, Lim, S-Y, Sixsmith, JD, Lukose, R, Souther, SJR, Rayasam, SDG, Saelens, JW, Chen, C-J, Seay, SA, Berney-Meyer, L, Magtanong, L, Vermeul, K, Pajanirassa, P, Jimenez, AE, Ng, TW, Tobin, DM, Porcelli, SA, Larsen, MH, Schmitz, JE, Haynes, BF, Jacobs, WR, Lee, S, and Frothingham, R. "Stable Expression of Lentiviral Antigens by Quality-Controlled Recombinant Mycobacterium bovis BCG Vectors." Clinical and vaccine immunology : CVI 22, no. 7 (July 2015): 726-741.

PMID
25924766
Full Text

Korioth-Schmitz, B, Perley, CC, Sixsmith, JD, Click, EM, Lee, S, Letvin, NL, and Frothingham, R. "Rhesus immune responses to SIV Gag expressed by recombinant BCG vectors are independent from pre-existing mycobacterial immunity." Vaccine 33, no. 42 (2015): 5715-5722.

Full Text

Sixsmith, JD, Panas, MW, Lee, S, Gillard, GO, White, K, Lifton, MA, Balachandran, H, Mach, L, Miller, JP, Lavine, C, DeMarco, CT, Tomaras, GD, Gee, C, Porcelli, SA, Larsen, MH, Frothingham, R, Schmitz, JE, Jacobs, WR, Haynes, BF, Letvin, NL, and Korioth-Schmitz, B. "Recombinant Mycobacterium bovis bacillus Calmette-Guérin vectors prime for strong cellular responses to simian immunodeficiency virus gag in rhesus macaques." Clinical and vaccine immunology : CVI 21, no. 10 (October 2014): 1385-1395.

PMID
25080550
Full Text

Sixsmith, JD, Panas, MW, Lee, S, Gillard, GO, White, K, Lifton, MA, Balachandran, H, Mach, L, Miller, JP, Lavine, C, DeMarco, CT, Tomaras, GD, Gee, C, Porcelli, SA, Larsen, MH, Frothingham, R, Schmitz, JE, Jr, JWR, Haynes, BF, Letvin, NL, and Korioth-Schmitz, B. "Recombinant Mycobacterium bovis Bacillus Calmette-Guerin Vectors Prime for Strong Cellular Responses to Simian Immunodeficiency Virus Gag in Rhesus Macaques." CLINICAL AND VACCINE IMMUNOLOGY 21, no. 10 (October 2014): 1385-1395.

Full Text

Perley, CC, Frahm, M, Click, EM, Dobos, KM, Ferrari, G, Stout, JE, and Frothingham, R. "The human antibody response to the surface of Mycobacterium tuberculosis." PLoS ONE 9, no. 6 (June 11, 2014).

Full Text

Roberts, LM, Tuladhar, S, Steele, SP, Riebe, KJ, Chen, C-J, Cumming, RI, Seay, S, Frothingham, R, Sempowski, GD, Kawula, TH, and Frelinger, JA. "Identification of early interactions between Francisella and the host." Infection and immunity 82, no. 6 (June 2014): 2504-2510.

PMID
24686053
Full Text

Holmer, SM, Evans, KS, Asfaw, YG, Saini, D, Schell, WA, Ledford, JG, Frothingham, R, Wright, JR, Sempowski, GD, and Perfect, JR. "Impact of surfactant protein D, interleukin-5, and eosinophilia on Cryptococcosis." Infection and immunity 82, no. 2 (February 2014): 683-693.

PMID
24478083
Full Text

Holmer, SM, Evans, KS, Asfaw, YG, Saini, D, Schell, WA, Ledford, JG, Frothingham, R, Wright, JR, Sempowski, GD, Perfect, JR, and Pirofski, L. "Impact of surfactant protein d, interleukin-5, and eosinophilia on cryptococcosis." Infection and immunity 82, no. 2 (February 2014): 683-693.

PMID
24277798
Full Text

Smith, KLJ, Saini, D, Bardarov, S, Larsen, M, Frothingham, R, Gandhi, NR, Jacobs, WR, Sturm, AW, and Lee, S. "Reduced virulence of an extensively drug-resistant outbreak strain of Mycobacterium tuberculosis in a murine model." PLoS ONE 9, no. 4 (January 2014): e94953-.

PMID
24733050
Full Text

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