Robert John Mentz, MD

Associate Professor of Medicine
Associate Professor in Population Health Sciences
Member in the Duke Clinical Research Institute
Campus mail Np-8062, Dcri. PO Box 17969, Durham, NC 27715
Phone (919) 668-7121
Email address

I am a cardiologist with a clinical and research interest in heart failure, including advanced therapies such as cardiac transplantation and mechanical assist devices or “heart pumps." I became a heart failure cardiologist in order to help patients manage their chronic disease over many months and years. I consider myself strongly committed to compassionate patient care with a focus on quality of life and patient preference.

My research interests are focused on treating co-morbid diseases in heart failure patients and improving outcomes across the cardiovascular spectrum through clinical trials and outcomes research. Below, you will find my specific research interests:

  •     Co-morbidity characterization (diabetes, sleep apnea, renal failure) in heart failure.
  •     Phenotypic characterization and risk prognostication of patients with heart failure.
  •     Role of surrogate and nonfatal endpoints in clinical heart failure trials.
  •     Biomarkers in heart failure.
  •     Novel pharmacological and non-pharmacological approaches to heart failure.
  •     Improving site-based heart failure research.
In Their Words

Education and Training

  • Fellowship, Advanced Heart Failure, Duke University School of Medicine, 2012 - 2013
  • Fellowship, Clinical Cardiology, Duke University School of Medicine, 2010 - 2012
  • Resident, Internal Medicine, Brigham and Women's Hospital, 2008 - 2010
  • Intern, Internal Medicine, Brigham and Women's Hospital, 2007 - 2008
  • M.D., Emory University, 2003


Pokorney, Sean D., Sana M. Al-Khatib, Jie-Lena Sun, Phillip Schulte, Christopher M. O’Connor, John R. Teerlink, Paul W. Armstrong, et al. “Sudden cardiac death after acute heart failure hospital admission: insights from ASCEND-HF..” In Eur J Heart Fail, 20:525–32, 2018.

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Greene, Stephen J., and Robert J. Mentz. “Potential advantages of torsemide in patients with heart failure: more than just a 'water pill'?.” Eur J Heart Fail 20, no. 3 (March 2018): 471–73.

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Barbagelata, Alejandro, Charles F. Bethea, Harry W. Severance, Robert J. Mentz, David Albert, Gregory W. Barsness, Viet T. Le, et al. “Smartphone ECG for evaluation of ST-segment elevation myocardial infarction (STEMI): Design of the ST LEUIS International Multicenter Study..” J Electrocardiol 51, no. 2 (March 2018): 260–64.

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Greene, Stephen, Adrian Hernandez, Jie Sun, Javed Butler, Paul Armstrong, Justin Ezekowitz, Marco Metra, et al. “PRIOR HEART FAILURE HOSPITALIZATION AMONG PATIENTS HOSPITALIZED FOR WORSENING CHRONIC HEART FAILURE: FROM THE ASCEND-HF TRIAL.” In Journal of the American College of Cardiology, 71:A796–A796. Elsevier BV, 2018.

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Luo, Nancy, Nicholas G. Ballew, Emily O’Brien, Melissa Greiner, Pamela Peterson, Bradley Hammill, N Chantelle Hardy, et al. “EARLY IMPACT OF GUIDELINE PUBLICATION ON ANGIOTENSIN-RECEPTOR NEPRILYSIN INHIBITOR USE AMONG PATIENTS HOSPITALIZED FOR HEART FAILURE.” In Journal of the American College of Cardiology, 71:A791–A791. Elsevier BV, 2018.

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Warraich, Haider, Dalane Kitzman, David Whellan, Duncan Pamela, Robert Mentz, Amy Pastva, Ben Nelson, and Gordon Reeves. “PHYSICAL FUNCTION, QUALITY OF LIFE, AND DEPRESSION IN ELDERLY, HOSPITALIZED PATIENTS WITH ACUTE DECOMPENSATED HEART FAILURE WITH PRESERVED VERSUS REDUCED EJECTION FRACTION: ANALYSIS FROM THE REHAB-HF TRIAL.” In Journal of the American College of Cardiology, 71:A1877–A1877. Elsevier BV, 2018.

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Bhatt, Ankeet S., Lauren B. Cooper, Andrew P. Ambrosy, Robert M. Clare, Adrian Coles, Emer Joyce, Arun Krishnamoorthy, et al. “Interaction of Body Mass Index on the Association Between N-Terminal-Pro-b-Type Natriuretic Peptide and Morbidity and Mortality in Patients With Acute Heart Failure: Findings From ASCEND-HF (Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure)..” J Am Heart Assoc 7, no. 3 (February 3, 2018).

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Fudim, Marat, Christopher M. O’Connor, Allison Dunning, Andrew P. Ambrosy, Paul W. Armstrong, Adrian Coles, Justin A. Ezekowitz, et al. “Aetiology, timing and clinical predictors of early vs. late readmission following index hospitalization for acute heart failure: insights from ASCEND-HF..” Eur J Heart Fail 20, no. 2 (February 2018): 304–14.

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