Sana Mustapha Al-Khatib, MD

Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail 7521 N Pavilion Bldg, Durham, NC 27715
Phone (919) 668-8649
Email address alkha001@duke.edu

Dr. Sana M. Al-Khatib is a tenured Professor of Medicine at Duke University Medical Center, a board-certified clinical electrophysiologist and an experienced clinical researcher in cardiac arrhythmias.  As a graduate of the NIH-funded Clinical Research Training Program, she is one of a few electrophysiologists nationwide with expertise in quantitative research methods. Her clinical expertise is in sudden cardiac death prevention, atrial fibrillation and ventricular arrhythmias, and implantable cardiac devices. Her research expertise lies in the design and conduct of clinical trials, outcomes research, and cost-effectiveness analyses. She is a recipient of a National Heart, Lung and Blood Institute’s R-01 grant titled “Implantable Cardioverter Defibrillator Therapy in Patients with Heart Failure” (2009-2013) and of an American Heart Association Career Development Award (2002-2006). She is a Co-Principal Investigator on an NHLBI-funded T-32 Postdoctoral Training in Cardiovascular Clinical Research and on several Agency of Healthcare Research and Quality sponsored R-01 grants including the “Duke Cardiovascular Center for Education and Research on Therapeutics.” She has more than 130 publications in peer-reviewed journals. She has established several collaborative research efforts both within and outside her institution. The goals of these collaborations are to synergize efforts aimed at improving the survival and quality of life of patients at risk for sudden cardiac death and those with atrial and ventricular arrhythmias through clinical trials and outcomes-based research and to evaluate study design and data analysis in order to improve the quality of research done in these arenas. Dr. Al-Khatib is an Associate Editor for the American Heart Journal and is on the Editorial Board for the Journal of Cardiovascular Electrophysiology. Dr. Al-Khatib serves on multiple national committees including the Heart Rhythm Society Board of Trustees, the Heart Rhythm Society Health Policy committee, the Heart Rhythm Society Legislative subcommittee, the Heart Rhythm Society Program Planning committee, the American College of Cardiology ICD Registry Steering committee, and the National Quality Forum Cardiovascular Steering committee.

In Their Words

Education and Training

  • Fellow in Cardiology, Medicine, Duke University, 1996 - 2000
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.D., American University of Beirut (Lebanon), 1993

Publications

Al-Khatib, Sana M., Gillian D. Sanders, J Thomas Bigger, Alfred E. Buxton, Robert M. Califf, Mark Carlson, Anne Curtis, et al. “Preventing tomorrow's sudden cardiac death today: part I: Current data on risk stratification for sudden cardiac death.” Am Heart J 153, no. 6 (June 2007): 941–50. https://doi.org/10.1016/j.ahj.2007.03.003.

PMID
17540194
Full Text

Sanders, Gillian D., Sana M. Al-Khatib, Elise Berliner, J Thomas Bigger, Alfred E. Buxton, Robert M. Califf, Mark Carlson, et al. “Preventing tomorrow's sudden cardiac death today: part II: Translating sudden cardiac death risk assessment strategies into practice and policy.” Am Heart J 153, no. 6 (June 2007): 951–59. https://doi.org/10.1016/j.ahj.2007.03.002.

PMID
17540195
Full Text

Curtis, Lesley H., Sana M. Al-Khatib, Alisa M. Shea, Bradley G. Hammill, Adrian F. Hernandez, and Kevin A. Schulman. “Sex differences in the use of ICDs for prevention of sudden cardiac death, 1999-2004.” In Circulation, 115:E576–E576. LIPPINCOTT WILLIAMS & WILKINS, 2007.

Scholars@Duke

Al-Khatib, Sana M., Anne S. Hellkamp, Kerry L. Lee, Daniel B. Mark, and Gust H. Bardy. “Implantable cardioverter defibrillator therapy improves the survival of patients with prior coronary revascularization: Data from the sudden cardiac death in heart failure trial.” In Journal of the American College of Cardiology, 49:12A-12A. ELSEVIER SCIENCE INC, 2007.

Scholars@Duke

Majidi, Mohamed, Andrzej S. Kosinski, Sana M. Al-Khatib, Miguel Lemmert, Ricardo G. Baeza, Suzanne W. Crater, Hein W. Wellens, Anton P. Gorgels, and Mitchell W. Krucoff. “Ventricular arrhythmia "bursts" in the setting of acute anterior infarct artery recanalization: A re-definition of "reperfusion arrhythmias".” In Journal of the American College of Cardiology, 49:17A-18A. ELSEVIER SCIENCE INC, 2007.

Scholars@Duke

Majidi, Mohamed, Andrzej S. Kosinski, Same M. Al-Khatib, Miguel Lemmert, Ricardo G. Baeza, Suzanne W. Crater, Hein J. Wellens, Anton P. Gorgels, and Mitchell W. Krucoff. “Reperfusion "BURST" arrhythmias as a biomarker of myocellular damage despite TIMI 3 epicardial flow.” In Journal of the American College of Cardiology, 49:223A-224A. ELSEVIER SCIENCE INC, 2007.

Scholars@Duke

Kong, Melissa S., Sana M. Al-Khatib, Linda K. Shaw, Robert M. Califf, and Christopher M. O’Connor. “Is rhythm control superior to rate control in patients with atrial fibrillation and diastolic heart failure?” In Journal of the American College of Cardiology, 49:5A-5A. ELSEVIER SCIENCE INC, 2007.

Scholars@Duke

Thomas, Kevin L., Sana M. Al-Khatib, Yuliya Lokhnygina, Scott D. Solomon, Lars Kober, Steven Zelenkofske, John J. McMurray, Robert M. Califf, and Eric J. Velazquez. “Amiodarone use after acute myocardial infarction complicated by heart failure and/or left ventricular dysfunction is associated with excess mortality.” In Circulation, 114:768–768. LIPPINCOTT WILLIAMS & WILKINS, 2006.

Scholars@Duke

Al-Khatib, Sana M., Linda K. Shaw, Christopher M. O’Connor, and Robert M. Califf. “Sudden cardiac death in patients with diastolic heart failure.” Circulation 114, no. 18 (October 31, 2006): 409–409.

Scholars@Duke

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