Sana Mustapha Al-Khatib, MD

Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail 7521 N Pavilion Bldg, Durham, NC 27715
Phone (919) 668-8649
Email address alkha001@mc.duke.edu

Dr. Sana M. Al-Khatib is a tenured Professor of Medicine at Duke University Medical Center, a board-certified clinical electrophysiologist and an experienced clinical researcher in cardiac arrhythmias.  As a graduate of the NIH-funded Clinical Research Training Program, she is one of a few electrophysiologists nationwide with expertise in quantitative research methods. Her clinical expertise is in sudden cardiac death prevention, atrial fibrillation and ventricular arrhythmias, and implantable cardiac devices. Her research expertise lies in the design and conduct of clinical trials, outcomes research, and cost-effectiveness analyses. She is a recipient of a National Heart, Lung and Blood Institute’s R-01 grant titled “Implantable Cardioverter Defibrillator Therapy in Patients with Heart Failure” (2009-2013) and of an American Heart Association Career Development Award (2002-2006). She is a Co-Principal Investigator on an NHLBI-funded T-32 Postdoctoral Training in Cardiovascular Clinical Research and on several Agency of Healthcare Research and Quality sponsored R-01 grants including the “Duke Cardiovascular Center for Education and Research on Therapeutics.” She has more than 130 publications in peer-reviewed journals. She has established several collaborative research efforts both within and outside her institution. The goals of these collaborations are to synergize efforts aimed at improving the survival and quality of life of patients at risk for sudden cardiac death and those with atrial and ventricular arrhythmias through clinical trials and outcomes-based research and to evaluate study design and data analysis in order to improve the quality of research done in these arenas. Dr. Al-Khatib is an Associate Editor for the American Heart Journal and is on the Editorial Board for the Journal of Cardiovascular Electrophysiology. Dr. Al-Khatib serves on multiple national committees including the Heart Rhythm Society Board of Trustees, the Heart Rhythm Society Health Policy committee, the Heart Rhythm Society Legislative subcommittee, the Heart Rhythm Society Program Planning committee, the American College of Cardiology ICD Registry Steering committee, and the National Quality Forum Cardiovascular Steering committee.

In Their Words

Education and Training

  • Fellow in Cardiology, Medicine, Duke University, 1996 - 2000
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.D., American University of Beirut (Lebannon), 1993

Publications

Patel, D, Hasselblad, V, Jackson, KP, Pokorney, SD, Daubert, JP, and Al-Khatib, SM. "Catheter ablation for ventricular tachycardia (VT) in patients with ischemic heart disease: a systematic review and a meta-analysis of randomized controlled trials." Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 45, no. 2 (March 2016): 111-117. (Review)

PMID
26695501
Full Text

Levine, GN, Bates, ER, Blankenship, JC, Bailey, SR, Bittl, JA, Cercek, B, Chambers, CE, Ellis, SG, Guyton, RA, Hollenberg, SM, Khot, UN, Lange, RA, Mauri, L, Mehran, R, Moussa, ID, Mukherjee, D, Ting, HH, O'Gara, PT, Kushner, FG, Ascheim, DD, Brindis, RG, Casey, DE, Chung, MK, de Lemos, JA, Diercks, DB, Fang, JC, Franklin, BA, Granger, CB, Krumholz, HM, Linderbaum, JA, Morrow, DA, Newby, LK, Ornato, JP, Ou, N, Radford, MJ, Tamis-Holland, JE, Tommaso, CL, Tracy, CM, Woo, YJ, and Zhao, DX. "2015 ACC/AHA/SCAI Focused Update on Primary Percutaneous Coronary Intervention for Patients With ST-Elevation Myocardial Infarction: An Update of the 2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention and the 2013 ACCF/AHA Guideline for the Management of ST-Elevation Myocardial Infarction." Journal of the American College of Cardiology 67, no. 10 (March 2016): 1235-1250. (Review)

PMID
26498666
Full Text

Levine, GN, Bates, ER, Blankenship, JC, Bailey, SR, Bittl, JA, Cercek, B, Chambers, CE, Ellis, SG, Guyton, RA, Hollenberg, SM, Khot, UN, Lange, RA, Mauri, L, Mehran, R, Moussa, ID, Mukherjee, D, Ting, HH, O'Gara, PT, Kushner, FG, Ascheim, DD, Brindis, RG, Casey, DE, Chung, MK, de Lemos, JA, Diercks, DB, Fang, JC, Franklin, BA, Granger, CB, Krumholz, HM, Linderbaum, JA, Morrow, DA, Newby, LK, Ornato, JP, Ou, N, Radford, MJ, Tamis-Holland, JE, Tommaso, CL, Tracy, CM, Woo, YJ, and Zhao, DX. "2015 ACC/AHA/SCAI Focused Update on Primary Percutaneous Coronary Intervention for Patients With ST-Elevation Myocardial Infarction: An Update of the 2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention and the 2013 ACCF/AHA Guideline for the Management of ST-Elevation Myocardial Infarction: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Society for Cardiovascular Angiography and Interventions." Circulation 133, no. 11 (March 2016): 1135-1147.

PMID
26490017
Full Text

Wilkoff, BL, Fauchier, L, Stiles, MK, Morillo, CA, Al-Khatib, SM, Almendral, J, Aguinaga, L, Berger, RD, Cuesta, A, Daubert, JP, Dubner, S, Ellenbogen, KA, Mark Estes, NA, Fenelon, G, Garcia, FC, Gasparini, M, Haines, DE, Healey, JS, Hurtwitz, JL, Keegan, R, Kolb, C, Kuck, K-H, Marinskis, G, Martinelli, M, McGuire, M, Molina, LG, Okumura, K, Proclemer, A, Russo, AM, Singh, JP, Swerdlow, CD, Teo, WS, Uribe, W, Viskin, S, Wang, C-C, and Zhang, S. "2015 HRS/EHRA/APHRS/SOLAECE expert consensus statement on optimal implantable cardioverter-defibrillator programming and testing." Heart rhythm 13, no. 2 (February 2016): e50-e86.

PMID
26607062
Full Text

Wilkoff, BL, Fauchier, L, Stiles, MK, Morillo, CA, Al-Khatib, SM, Almendral, J, Aguinaga, L, Berger, RD, Cuesta, A, Daubert, JP, Dubner, S, Ellenbogen, KA, Estes, NAM, Fenelon, G, Garcia, FC, Gasparini, M, Haines, DE, Healey, JS, Hurtwitz, JL, Keegan, R, Kolb, C, Kuck, K-H, Marinskis, G, Martinelli, M, Mcguire, M, Molina, LG, Okumura, K, Proclemer, A, Russo, AM, Singh, JP, Swerdlow, CD, Teo, WS, Uribe, W, Viskin, S, Wang, C-C, Zhang, S, and Document Reviewers, . "2015 HRS/EHRA/APHRS/SOLAECE expert consensus statement on optimal implantable cardioverter-defibrillator programming and testing." Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 18, no. 2 (February 2016): 159-183.

PMID
26585598
Full Text

Zeitler, EP, Al-Khatib, SM, Slotwiner, D, Kumar, UN, Varosy, P, Van Wagoner, DR, Marcus, GM, Kusumoto, FM, and Blum, L. "Proceedings from Heart Rhythm Society's emerging technologies forum, Boston, MA, May 12, 2015." Heart rhythm 13, no. 2 (February 2016): e39-e49.

PMID
26801401
Full Text

2010 ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM GUIDELINES FOR THE DIAGNOSIS AND MANAGEMENT OF PATIENTS WITH THORACIC AORTIC DISEASE REPRESENTATIVE MEMBERS*, , Hiratzka, LF, Creager, MA, Isselbacher, EM, Svensson, LG, 2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease Representative Members*, , Nishimura, RA, Bonow, RO, Guyton, RA, Sundt, TM, ACC/AHA TASK FORCE MEMBERS, , Halperin, JL, Levine, GN, Anderson, JL, Albert, NM, Al-Khatib, SM, Birtcher, KK, and Bozkurt, B et al. "Surgery for Aortic Dilatation in Patients With Bicuspid Aortic Valves: A Statement of Clarification From the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines." Circulation 133, no. 7 (February 2016): 680-686.

PMID
26637530
Full Text

Wilkoff, BL, Fauchier, L, Stiles, MK, Morillo, CA, Al-Khatib, SM, Almendral, J, Aguinaga, L, Berger, RD, Cuesta, A, Daubert, JP, Dubner, S, Ellenbogen, KA, Estes, NAM, Fenelon, G, Garcia, FC, Gasparini, M, Haines, DE, Healey, JS, Hurtwitz, JL, Keegan, R, Kolb, C, Kuck, K-H, Marinskis, G, Martinelli, M, McGuire, M, Molina, LG, Okumura, K, Proclemer, A, Russo, AM, Singh, JP, Swerdlow, CD, Teo, WS, Uribe, W, Viskin, S, Wang, C-C, and Zhang, S. "2015 HRS/EHRA/APHRS/SOLAECE expert consensus statement on optimal implantable cardioverter-defibrillator programming and testing." Journal of arrhythmia 32, no. 1 (February 2016): 1-28.

PMID
26949427
Full Text

Zeitler, EP, Al-Khatib, SM, Jr, DJP, Kessler, LG, Kirtane, AJ, Kong, DF, Laschinger, J, Marinac-Dabic, D, Morice, M-C, Reed, T, Sedrakyan, A, Stein, KM, Tcheng, J, and Krucoff, MW. "Predictable and Su Stainable Implementation of National Cardiovascular Registries (PASSION) infrastructure: A think tank report from Medical Device Epidemiological Network Initiative (MDEpiNet)." AMERICAN HEART JOURNAL 171, no. 1 (January 2016): 64-72.

Full Text

Durheim, MT, Cyr, DD, Lopes, RD, Thomas, LE, Tsuang, WM, Gersh, BJ, Held, C, Wallentin, L, Granger, CB, Palmer, SM, and Al-Khatib, SM. "Chronic obstructive pulmonary disease in patients with atrial fibrillation: Insights from the ARISTOTLE trial." International journal of cardiology 202 (January 2016): 589-594.

PMID
26447668
Full Text

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