Sarah Sammons, MD

Assistant Professor of Medicine

Member of the Duke Cancer Institute

Email address sarah.sammons@duke.edu

Education and Training

College/University
University of Delaware

Medical School
Sidney Kimmel Medical College - Thomas Jefferson University

Residency
University of Maryland

Career and Research Goals

My career focus is in the treatment of women with aggressive sub-types of breast cancer such as basal-like (triple negative) and ERBB-2 amplified. My current research goals are finding therapeutic strategies to target the ERBB family of receptors specifically EGFR and ERBB3 in basal-like breast cancer. I hope to characterize the role somatic ERBB3 mutations in primary and metastatic basal type breast cancer. I also have a special interest in early phase drug development and toxicity management.

Honors, awards and distinctions

Alpha Omega Alpha Honor Society

Education and Training

Hematology-Oncology Fellowship, Duke University School of Medicine, 2015 - 2018
Internal Medicine Residency, University of Maryland School of Medicine, 2012 - 2015
M.D., Jefferson Medical College of Thomas Jefferson University, 2012

Grants

Publications

Sambade, Maria J., Grace Prince, Allison M. Deal, Dimitri Trembath, Megan McKee, Amy Garrett, Kevin Keith, et al. “Examination and prognostic implications of the unique microenvironment of breast cancer brain metastases..” Breast Cancer Res Treat 176, no. 2 (July 2019): 321–28. https://doi.org/10.1007/s10549-019-05211-1.

PMID

31016641

Full Text

Dent, Susan, Chiara Melloni, Josee Ivars, Sarah Sammons, and Gretchen Kimmick. “Cardiotoxicities of Modern Treatments in Breast Cancer..” Curr Treat Options Cardiovasc Med 21, no. 7 (June 15, 2019). https://doi.org/10.1007/s11936-019-0738-z.

PMID

31203459

Full Text

Sammons, Sarah, Noah S. Kornblum, and Kimberly L. Blackwell. “Fulvestrant-Based Combination Therapy for Second-Line Treatment of Hormone Receptor-Positive Advanced Breast Cancer..” Target Oncol 14, no. 1 (February 2019): 1–12. https://doi.org/10.1007/s11523-018-0587-9.

PMID

30136059

Full Text

Sammons, Sarah, Noah S. Kornblum, and Kimberly L. Blackwell. “Correction to: Fulvestrant-Based Combination Therapy for Second-Line Treatment of Hormone Receptor-Positive Advanced Breast Cancer..” Target Oncol 14, no. 1 (February 2019). https://doi.org/10.1007/s11523-018-0614-x.

PMID

30535552

Full Text

Force, Jeremy, Lynn J. Howie, Sara E. Abbott, Rex Bentley, P Kelly Marcom, Gretchen Kimmick, Kelly Westbrook, et al. “Early Stage HER2-Positive Breast Cancers Not Achieving a pCR From Neoadjuvant Trastuzumab- or Pertuzumab-Based Regimens Have an Immunosuppressive Phenotype..” Clin Breast Cancer 18, no. 5 (October 2018): 410–17. https://doi.org/10.1016/j.clbc.2018.02.010.

PMID

29615305

Full Text

Sammons, S., M. McNamara, A. K. S. Salama, and J. Crawford. “Immune checkpoint inhibition.” In Side Effects of Medical Cancer Therapy: Prevention and Treatment: Second Edition, 315–53, 2018. https://doi.org/10.1007/978-3-319-70253-7_12.

Full Text

Narloch, Jessica L., S Harrison Farber, Sarah Sammons, Frances McSherry, James E. Herndon, Jenny K. Hoang, Fang-Fang Yin, et al. “Biopsy of enlarging lesions after stereotactic radiosurgery for brain metastases frequently reveals radiation necrosis..” Neuro Oncol 19, no. 10 (October 1, 2017): 1391–97. https://doi.org/10.1093/neuonc/nox090.

PMID

28472527

Full Text

Sammons, Sarah L., Donna L. Topping, and Kimberly L. Blackwell. “HR+, HER2- Advanced Breast Cancer and CDK4/6 Inhibitors: Mode of Action, Clinical Activity, and Safety Profiles..” Curr Cancer Drug Targets 17, no. 7 (2017): 637–49. https://doi.org/10.2174/1568009617666170330120452.

PMID

28359238

Full Text