Steven Patierno, PhD

Professor of Medicine
Professor of Pharmacology and Cancer Biology
Professor in Family Medicine and Community Health
Core Faculty Member, Duke-Margolis Center for Health Policy
Member of the Duke Cancer Institute
Campus mail 10 Bryan Searle Drive, Seeley Mudd Building, Suite 413, Durham, NC 27710
Phone (919) 613-5093
Email address steven.patierno@duke.edu

Patierno's current translational research interests are focused on the genomics molecular biology of cancer disparities, cancer biology, molecular pharmacology and targeted experimental therapeutics to control prostate, breast and lung tumor aggressiveness. He is an internationally recognized expert in cancer control, cancer causation and molecular carcinogenesis, which includes a broad spectrum of laboratory and population level research.   Patierno is also actively engaged in cancer health disparities and healthcare delivery research focused on patient navigation, survivorship, community-based interventions, mHealth, implementation sciences, cancer care economics, and policy.

Education and Training

  • Postdoctoral Training, Norris Comprehensive Cancer, University of Southern California, 1986 - 1988
  • Ph.D., University of Texas Medical School, Houston, 1985
  • B.S., University of Connecticut, 1981

Publications

Patierno, Brendon M., Wen-Chi Foo, Tyler Allen, Jason A. Somarelli, Kathryn E. Ware, Santosh Gupta, Sandra Wise, et al. “Characterization of a castrate-resistant prostate cancer xenograft derived from a patient of West African ancestry.” In Prostate Cancer Prostatic Dis, 2021. https://doi.org/10.1038/s41391-021-00460-y.

PMID
34645983
Full Text

George, Daniel J., Susan Halabi, Elisabeth I. Heath, A Oliver Sartor, Guru P. Sonpavde, Devika Das, Rhonda L. Bitting, et al. “A prospective trial of abiraterone acetate plus prednisone in Black and White men with metastatic castrate-resistant prostate cancer.” Cancer 127, no. 16 (August 15, 2021): 2954–65. https://doi.org/10.1002/cncr.33589.

PMID
33951180
Full Text

Al Abo, Muthana, Terry Hyslop, Xiaodi Qin, Kouros Owzar, Daniel J. George, Steven R. Patierno, and Jennifer A. Freedman. “Differential alternative RNA splicing and transcription events between tumors from African American and White patients in The Cancer Genome Atlas.” Genomics 113, no. 3 (May 2021): 1234–46. https://doi.org/10.1016/j.ygeno.2021.02.020.

PMID
33705884
Full Text

Deveaux, April E., Tyler A. Allen, Muthana Al Abo, Xiaodi Qin, Dadong Zhang, Brendon M. Patierno, Lin Gu, et al. “RNA splicing and aggregate gene expression differences in lung squamous cell carcinoma between patients of West African and European ancestry.” Lung Cancer 153 (March 2021): 90–98. https://doi.org/10.1016/j.lungcan.2021.01.015.

PMID
33465699
Full Text

Shah, Anand, Thomas J. Polascik, Daniel J. George, John Anderson, Terry Hyslop, Alicia M. Ellis, Andrew J. Armstrong, et al. “Implementation and Impact of a Risk-Stratified Prostate Cancer Screening Algorithm as a Clinical Decision Support Tool in a Primary Care Network.” In J Gen Intern Med, 36:92–99, 2021. https://doi.org/10.1007/s11606-020-06124-2.

PMID
32875501
Full Text

Allen, Tyler A., Mark M. Cullen, Nathan Hawkey, Hiroyuki Mochizuki, Lan Nguyen, Elyse Schechter, Luke Borst, et al. “A Zebrafish Model of Metastatic Colonization Pinpoints Cellular Mechanisms of Circulating Tumor Cell Extravasation.” Front Oncol 11 (2021): 641187. https://doi.org/10.3389/fonc.2021.641187.

PMID
34631514
Full Text

Allen, Tyler, Gary Lipton, Alexander B. Sibley, Patrick Healy, Brendon Patierno, Bonnie Lacroix, Steven Patierno, et al. “Abstract 3507: Race-related genetic variation and response to secondary hormonal therapy in metastatic castration-resistant prostate cancer.” In Cancer Research, 80:3507–3507. American Association for Cancer Research (AACR), 2020. https://doi.org/10.1158/1538-7445.am2020-3507.

Full Text

Crankshaw, Sydnee, Julia Butt, Jennifer M. Gierisch, Nadine J. Barrett, Sabrena Mervin-Blake, Kevin Oeffinger, Steven Patierno, Valarie Worthy, Ronald Godbee, and Meira Epplein. “The Durham Initiative for Stomach Health (DISH): a pilot community-based Helicobacter pylori education and screening study.” Bmc Gastroenterol 20, no. 1 (August 6, 2020): 261. https://doi.org/10.1186/s12876-020-01405-w.

PMID
32762641
Full Text

Hildenbrand, Jordan, Cheyenne Corbett, Debra Davis, Kris Herring, Susan Locke, Jesse Troy, Steve Wolf, et al. “Digital Supportive Care Awareness and Navigation (D-SCAN): Qualitative and Quantitative Results of a Pilot Randomized Trial in Patients with Advanced Cancer.” In Journal of Pain and Symptom Management, 60:272–272, 2020.

Scholars@Duke

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