Vivian Hou Chu, MD

Associate Professor
Member in the Duke Clinical Research Institute
Campus mail Duke Box 102359, DIV of Infectious Diseases, Durham, NC 27710
Phone (919) 668-7174
Email address vivian.chu@duke.edu

Dr. Chu's clinical research is focused on staphylococci and endocarditis (IE).  She is the director of the International Collaboration on Endocarditis (ICE), a group of investigators from 78 sites in 32 countries worldwide that is dedicated to further the understanding of infective endocarditis.  The ICE database comprises > 5000 cases of endocarditis and is designed to answer questions that could not be answered from a single-center study. The current focus of this group is surgical-decision making in the treatment of endocarditis. Another major focus of Dr. Chu's research is on the relationship between oral hygiene and risk for developing infective endocarditis.

Education and Training

  • Fellow in Infectious Diseases, Medicine, Duke University, 2003 - 2006
  • Medical Resident, Medicine, Duke University, 2000 - 2003
  • M.D., Columbia University, 2000

Publications

Dickerman, Stuart A., Bruno Barsic, Vivian H. Chu, V. G. Fowler, Paul A. Pappas, and Arnold Bayer. “Medical vs. Surgical Management of Perivalvular Abscess in Infective Endocarditis: A Propensity Analysis From the International Collaboration on Endocarditis Prospective Cohort Study (ICE-PCS).” Circulation 124, no. 21 (November 22, 2011).

Scholars@Duke

Nienaber, Juhsien J. C., Batu K. Sharma Kuinkel, Michael Clarke-Pearson, Supaporn Lamlertthon, Lawrence Park, Thomas H. Rude, Steve Barriere, et al. “Methicillin-susceptible Staphylococcus aureus endocarditis isolates are associated with clonal complex 30 genotype and a distinct repertoire of enterotoxins and adhesins..” J Infect Dis 204, no. 5 (September 1, 2011): 704–13. https://doi.org/10.1093/infdis/jir389.

PMID
21844296
Full Text

Thornhill, Martin H., Mark J. Dayer, Jamie M. Forde, G Ralph Corey, Vivian H. Chu, David J. Couper, and Peter B. Lockhart. “Impact of the NICE guideline recommending cessation of antibiotic prophylaxis for prevention of infective endocarditis: before and after study..” Bmj 342 (May 3, 2011). https://doi.org/10.1136/bmj.d2392.

PMID
21540258
Full Text

Dayer, M., M. H. Thornhill, J. M. Forde, G. R. Corey, V. H. Chu, D. J. Couper, and P. B. Lockhart. “No significant increase in the incidence of infective endocarditis following the cessation of antibiotic prophylaxis for dental procedures.” In European Heart Journal, 31:467–467. OXFORD UNIV PRESS, 2010.

Scholars@Duke

Lalani, Tahaniyat, Christopher H. Cabell, Daniel K. Benjamin, Ovidiu Lasca, Christoph Naber, Vance G. Fowler, G Ralph Corey, et al. “Analysis of the impact of early surgery on in-hospital mortality of native valve endocarditis: use of propensity score and instrumental variable methods to adjust for treatment-selection bias..” Circulation 121, no. 8 (March 2, 2010): 1005–13. https://doi.org/10.1161/CIRCULATIONAHA.109.864488.

PMID
20159831
Full Text

Eisen, Damon P., G Ralph Corey, Emma S. McBryde, Vance G. Fowler, Jose M. Miro, Chris H. Cabell, Alan C. Street, et al. “Reduced valve replacement surgery and complication rate in Staphylococcus aureus endocarditis patients receiving acetyl-salicylic acid..” J Infect 58, no. 5 (May 2009): 332–38. https://doi.org/10.1016/j.jinf.2009.03.006.

PMID
19342103
Full Text

Chu, V. H., J. M. Miro, B. Hoen, C. H. Cabell, P. A. Pappas, P. Jones, M. E. Stryjewski, et al. “Coagulase-negative staphylococcal prosthetic valve endocarditis--a contemporary update based on the International Collaboration on Endocarditis: prospective cohort study..” Heart 95, no. 7 (April 2009): 570–76. https://doi.org/10.1136/hrt.2008.152975.

PMID
18952633
Full Text

Murdoch, David R., G Ralph Corey, Bruno Hoen, José M. Miró, Vance G. Fowler, Arnold S. Bayer, Adolf W. Karchmer, et al. “Clinical presentation, etiology, and outcome of infective endocarditis in the 21st century: the International Collaboration on Endocarditis-Prospective Cohort Study..” Arch Intern Med 169, no. 5 (March 9, 2009): 463–73. https://doi.org/10.1001/archinternmed.2008.603.

PMID
19273776
Full Text

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