New funding awards - February 2016

Sponsored Research

Gillian D. Schmidler of Cardiology has received a sub-award through Tufts University for a project entitled "Panel on Cost Effectiveness in Health and Medicine, Medical Editor." Total funding will be $11,200.

Daniel S. Sinden (Mentor: Geoffrey Pitt) of Cardiology has received an award (1F30-HL131217-01) from the National Institutes of Health for a project entitled "Fibroblast Growth Factor Homologous Factor Modulation and Effect on Cardiac Ion Channel Trafficking." Total funding will be $83,140.

Kevin Thomas of Cardiology has received an award from the Patient-Centered Outcomes Research Institute for a project entitled "Educational Videos to Reduce Racial Disparities in ICD therapy Via Innovative Designs (VIVID)." Total funding will be $1,958,915.

Courtney H. Van Houtven of General Internal Medicine has received a sub-award (R01-CA196576) through Temple University for a project entitled "Informal caregiver burden in advanced cancer: Economic and health outcomes." Total funding will be $59,884.

Daniel W. Belsky of Geriatrics has received an award from the Jacobs Foundation for a project entitled "Early Career Research Fellowship." Total funding will be $160,585.

Nelson J. Chao of Hematological Malignancies and Cellular Therapy has received an award from the Gateway for Cancer Research for a project entitled "A Controlled Study of Stem Cell Transplantation Medical Home Care Compared to Standard Hospital Care." Total funding will be $455,623.

Vance G. Fowler Jr. of Infectious Diseases has received an award (2K24-AI093969-06) from the National Institutes of Health for a project entitled "Mentoring Patient Oriented Research in Antibiotic-Resistant Bacteria." Total funding will be $859,473.

Aimee K. Zaas of Infectious Diseases has received an award from the Association of American Medical Colleges for a project entitled "Learning Health System Research Champion Award." Total funding will be $5,000.

Andrew B. Nixon of Medical Oncology has received a sub-award through the Cleveland Clinic Foundation for a project entitled "Dovitinib in Treating Patients with Recurrent or Progressive Glioblastoma." Total funding will be $63,180.

Tiffani White (Mentor: Susan B. Gurley) of Nephrology has received an award from the American Diabetes Association for a project entitled "The role of immune responses in the development of diabetic kidney disease." Total funding will be $53,680.

Robert M. Tighe of Pulmonary, Allergy, and Critical Care Medicine has received a sub-award (R01-ES013611) through the University of North Carolina - Chapel Hill for a project entitled "Diesel-induced Alterations of Influenza Infectivity." Total funding will be $204,452.

Industry-sponsored Clinical Trials

James P. Daubert of Cardiology has received an award from Medtronic, Inc. for a project entitled "MED-013: MR-HIS." Total funding will be $80,081.

Geoffrey S. Ginsburg of Cardiology has received an award through the Institute for Medical Research, Inc. for a project entitled "Resilience to Infection: A community-based research approach." Total funding will be $109,239.

Igor Klem of Cardiology has received an award from Bayer Healthcare Pharmaceuticals, Inc for a project entitled "Multicenter open-label study to evaluate efficacy of gadobutrol-enhanced cardiac magnetic resonance imaging (CMRI) for detection of significant coronary artery disease (CAD) in subjects with known or suspected CAD by a blinded image analysis." Total funding will be $236,666.

David F. Kong of Cardiology has received an award from Medtronic, Inc. for a project entitled "SAFE PCI STEMI." Total funding will be $4,500,000.

Martin A. Moseley III of Cardiology has received an award from Kineta, Inc for a project entitled "Proteomics Shared Resource - Kineta SRA." Total funding will be $4,204.

Manesh R. Patel of Cardiology has received an award from the Thoratec Corporation for a project entitled "Shield II." Total funding will be $59,000.

Manal F. Abdelmalek of Gastroenterology has received an award from Conatus Pharmaceuticals for a project entitled "Conatus IDN-6556-12 A Multicenter, Randomized, Double-Blind, Placebo controlled Trial of Emricasan (IDN-6556), an Oral Caspase Inhibitor, in Subjects with Non-alcoholic Steatohepatitis (NASH) Fibrosis." Total funding will be $193,346.

Manal F. Abdelmalek of Gastroenterology has received an award from Intercept Pharmaceuticals, Inc for a project entitled "Intercept 747-303 - A phase 3 double-blind, randomized, long-term, placebo-controlled, multicenter study evaluating the safety and efficacy of Obeticholic acid in subjects with Nonalcoholic Steatohepatitis." Total funding will be $109,104.

Rodger A. Liddle of Gastroenterology has received an award from Biocryst Corporation for a project entitled "Effects of BCX4161 on the Pancreas." Total funding will be $121,998.

Andrew J. Muir of Gastroenterology has received an award from TaiwanJ Pharmaceuticals Co. Ltd for a project entitled "TaiwanJ JKB 122AIH . . . A Phase 2, Pilot Study of JKB-122 to Assess Liver Tests (ALT) in Autoimmune Hepatitis Patients Who Are Refractory or Intolerant to Current Therapies." Total funding will be $83,154.

Cristina Gasparetto of Hematological Malignancies and Cellular Therapy has received an award from Karyopharm Therapeutics for a project entitled "Phase II, randomized, double-blinded, placebo-controlled multicenter study of Selinexor KPT-330 Carlf, and Dexa, in R/R MM pts who previously have been treated with proteasome inhibitor and an immunomodulatory drug." Total funding will be $182,224.

Murat O. Arcasoy of Hematology has received an award from Janssen Research & Development, LLC for a project entitled "A Randomized, Single-Blind, Multicenter Phase 2 Study to Evaluate the Activity of 2 Dose Levels of Imetelstat in Subjects with Intermediate-2 or High-Risk Myelofibrosis (MF) Relapsed/Refractory to Janus Kinase (JAK) Inhibitor." Total funding will be $211,605.

Ara D. Metjian of Hematology has received an award from Ablynx for a project entitled "A Phase III Trial with Caplacizumab in Patients with Acquired Thrombotic Thrombocytopenic Purpura." Total funding will be $83,962.

J. Brice Weinberg of Hematology has received an award from the Laboratory Corporation of America Holdings for a project entitled "Use of Biomarkers in Chronic Lymphocytic Leukemia for Clinical Decision Making." Total funding will be $783,979.

Ephraim L. Tsalik of Infectious Diseases has received an award through Ibis Biosciences, Inc. for a project entitled "Feasibility for Predicting Warfighter Health Using Transcriptional Markers on the MAP Platform." Total funding will be $391,000.

Kimberly L. Blackwell of Medical Oncology has received an award from Novartis Pharmaceuticals Corporation for a project entitled "A randomized doubleblind, placebo controlled study of ribociclib in combination w/fulvestrant for the treatment of postmenopausal women w/hormone receptor positive, HER2-, advanced breast cancer who have received no or only 1line of prior endo treatment." Total funding will be $273,170.

Jeffrey Crawford of Medical Oncology has received an award from Clinipace, Inc. for a project entitled "A phase III prospective double blind placebo controlled randomized study of adjuvant Medi4736 in completely resected non-small cell lung cancer." Total funding will be $162,420.

Michael A. Morse of Medical Oncology has received an award from Bayer HealthCare AG for a project entitled "A Phase I study of Niclosamide in patients with resectable colon cancer."

Shelby Reed of Other Medicine has received an award from Evalve Inc. for a project entitled "Patient Preferences - Mitral Valve Regurgitation." Total funding will be $586,079.

Njira L. Lugogo of Pulmonary, Allergy, and Critical Care Medicine has received an award from AstraZeneca AB for a project entitled "TROPOS." Total funding will be $187,324.

Virginia B. Kraus of Rheumatology and Immunology has received an award from Bioiberica, S.A. for a project entitled "Macrophage Model System." Total funding will be $80,000.

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