New funding awards - February 2018

Sponsored Research

Jonathan Campbell of Endocrinology, Metabolism, and Nutrition has received an award from the American Diabetes Association for a project entitled "Mechanisms of GIPR action as novel therapeutic targets for T2D." Total funding will be $552,000.

Andrew J. Muir of Gastroenterology has received a sub-award through The Kirby Institute for a project entitled "Smart-C - A phase IIIb open-label, multicentre, international randomised controlled trial of simplified treatment monitoring for 8 weeks glecapevir (300 gm)/pibrentasvis (120mg) in chronic HCV treatment naive patients without cirrhosis." Total funding will be $72,302.

Rowena J. Dolor of General Internal Medicine has received a sub-award (1R01-DA044248-01) through the University of Cincinnati for a project entitled "EMPOWER." Total funding will be $96,612.

Connie Bales of Geriatrics has received an award from the Egg Nutrition Center for a project entitled "Balanced (Egg) Protein during Obesity Reduction: Differential Responses in Insulin Resistance by Race." Total funding will be $60,723.

Kimberly Johnson of Geriatrics has received an award (1U54-MD012530-01) from the National Institutes of Health for a project entitled "Administrative Core."

Kimberly Johnson of Geriatrics has received an award from the Patient-Centered Outcomes Research Institute for a project entitled "Reducing Disparities in the Quality of Palliative Care for Older African Americans Through Improved Advance Care Planning." Total funding will be $1,281,684.

Jason E. Stout of Infectious Diseases has received a sub-award (NU52PS004698) through the NC Department of Health and Human Services for a project entitled "Epidemiology/General Communicable Disease Control." Total funding will be $85,933.

Cameron R. Wolfe of Infectious Diseases has received an award from the American College of Chest Physicians for a project entitled "Duke Continuing Medical Educational Program: CHEST." Total funding will be $53,675.

Laura P. Svetkey of Nephrology has received an award (1U54-MD012530-01) from the National Institutes of Health for a project entitled "Investigator Development Core", a part of Kimberly Johnson's project entitled "Duke Health Disparities Research Center."

Hakim Ali of Pulmonary, Allergy, and Critical Care Medicine has received an award from the International Society for Heart & Lung Transplantation for a project entitled "Clinical features of lung transplant recipients with prolonged survival (>15 years) from the ISHLT registry." Total funding will be $7,500.

Christopher Cox of Pulmonary, Allergy, and Critical Care Medicine has received an award (1U54-MD012530-01) from the National Institutes of Health for a project entitled "Research Project 3", a part of Kimberly Johnson's project entitled "Duke Health Disparities Research Center.”

Isaretta L. Riley of Pulmonary, Allergy, and Critical Care Medicine has received a sub-award through the American Academy of Family Physicians Foundation for a project entitled "PREPARE - PeRson EmPoweRed Asthma RElief Study." Total funding will be $58,800.

Laurie D. Snyder of Pulmonary, Allergy, and Critical Care Medicine has received an award through Dartmouth College for a project entitled "CF Lung Transplant Transition Learning and Leadership Collaborative (LTT LLC)." Total funding will be $15,660.

Laurie D. Snyder of Pulmonary, Allergy, and Critical Care Medicine has received a sub-award (1R01-DK111638-01A1) through the University of Pennsylvania for a project entitled "Clinical and Molecular Epidemiology of Acute Kidney Injury After Lung Transplant." Total funding will be $63,353.

Industry-sponsored Clinical Trials

Christopher Granger of Cardiology has received an award from Novartis Pharmaceuticals Corporation for a project entitled "PARADISE." Total funding will be $36,747.

Renato D. Lopes of Cardiology has received an award from Pfizer, Inc. for a project entitled "Educational Preceptorship Agreement." Total funding will be $99,999.

Martin A. Moseley III of Cardiology has received an award from the Instrumentation Laboratory Company for a project entitled "Project BGG." Total funding will be $9,117.

Tracy Y. Wang of Cardiology has received an award from the Bristol-Myers Squibb Company for a project entitled "BMS Duke Drug Development Series." Total funding will be $150,675.

Jenny Tong of Endocrinology, Metabolism, and Nutrition has received an award from Eiger BioPharmaceuticals, Inc. for a project entitled "Exendin 9-39 in Patients with Postbariatric Hypoglycemia." Total funding will be $131,450.

Jane E. Onken of Gastroenterology has received an award from Janssen Research & Development, LLC for a project entitled "A Phase 1, Open-label, Drug Interaction Study to Evaluate the Effect of Ustekinumab on Cytochrome P450 Enzyme Activities Following Induction and Maintenance Dosing in Participants with Moderate to Severe Crohn's Disease." Total funding will be $177,233.

Danielle M. Brander of Hematological Malignancies and Cellular Therapy has received an award from TG Therapeutics, Inc for a project entitled "An Open Label Compassionate Use Trial of Ublituximab and TGR-1202 in Combination or as Single Agents in Subjects Currently receiving Treatment on Ublituximab and/or TGR-1202 Trials with B-cell Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia." Total funding will be $20,319.

Nelson J. Chao of Hematological Malignancies and Cellular Therapy has received an award through SRI International for a project entitled "Clinical Validation and Supply of SRI Radiation Biodosimeter." Total funding will be $127,660.

David Rizzieri of Hematological Malignancies and Cellular Therapy has received an award from FORMA Therapeutics, Inc. for a project entitled "A Phase I/Ib, Multicenter, Open-Label, Dose-Escalation Study of FT-2102 as a Single agent and in Combination with Azacitidine in patients with Acute Myeloid Leukemia or Myelodysplastic Syndrome with an IDH1 Mutation." Total funding will be $163,139.

David Rizzieri of Hematological Malignancies and Cellular Therapy has received an award from Eureka Therapeutics, Inc. for a project entitled "Phase 1 study of ET190LI - ARTEMIS T Cells in Relapsed and Refractory CD19 + Non-Hodgkin's Lymphoma." Total funding will be $5,500,134.

Andrew Armstrong of Medical Oncology has received an award from AstraZeneca Pharmaceuticals, LP for a project entitled "A Phase III, Open Label, Randomized Study to Assess the Efficacy and Safety of Olaparib (Lynparzaї) Versus Enzalutamide or Abiraterone Acetate in Men with Metastatic Castration-Resistant Prostate Canc." Total funding will be $150,769.

Michael A. Morse of Medical Oncology has received an award from H3 Biomedicine, Inc. for a project entitled "An Open-Label Multicenter Phase 1 Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of H3B-6527 in Subjects With Advanced Hepatocellular Carcinoma or Intrahepatic Cholangiocarcinoma." Total funding will be $627,112.

Andrew B. Nixon of Medical Oncology has received an award from MedPacto, Inc for a project entitled "Blood-based Biomarker Profiling for TEW-7197." Total funding will be $375,490.

Thomas Stinchcombe of Medical Oncology has received an award from TESARO for a project entitled "A Randomized Phase II Study Evaluating Pembrolizumab vs Topotecan in the Second-line Treatment of Patients with Small Cell Lung Cancer." Total funding will be $516,094.

George Cheng of Pulmonary, Allergy, and Critical Care Medicine has received an award from Intuitive Surgical, Inc. for a project entitled "Evaluation of Electromagnetic Navigation Bronchoscopy with real-time CT scan to assess Navigation to Peripheral Lung Lesions." Total funding will be $50,000.

Alice L. Gray of Pulmonary, Allergy, and Critical Care Medicine has received an award from Vertex Pharmaceuticals Inc. for a project entitled "Phase 3b, Randomized, Double-blind, Placebo-controlled, Parallel Group Study to Assess the Safety, Efficacy, and Tolerability of Tezacaftor/Ivacaftor (TEZ/IVA) in an Orkambi-experienced Population." Total funding will be $64,939.

Yuh Chin T. Huang of Pulmonary, Allergy, and Critical Care Medicine has received an award from AstraZeneca Pharmaceuticals, LP for a project entitled "Effects of glycopryrrolate/formoterol (Bevespi) on ventilation and gas exchange abnormalities in COPD assessed by 129Xe MRI." Total funding will be $244,945.

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