New funding awards - May 2018

Sponsored Research

Geoffrey S. Ginsburg of Cardiology has received an award (3U01-HG007282-04S3) from the National Institutes of Health for a project entitled "Implementation, Adoption, and Utility of Family History in Diverse Care Settings." Total funding will be $922,804.

Robert J. Lefkowitz of Cardiology has received an award from the Howard Hughes Medical Institute for a project entitled "Molecular Regulation of Cardiovascular G Protein Coupled Receptors." Total funding will be $38,000.

Eric D. Peterson of Cardiology has received an award from the Society of Thoracic Surgeons for a project entitled "Data Warehousing Center for the Adult Cardiac Surgery, Congenital and Thoracic Databases: 2016 STS Amendments." Total funding will be $398,143.

Eric D. Peterson of Cardiology has received an award from the Society of Thoracic Surgeons for a project entitled "Data Warehousing Center for the Adult Cardiac Surgery, Congenital and Thoracic Databases: 2015 STS Amendments." Total funding will be $277,930.

Megan Capozzi (Mentor: David D'Alessio) of Endocrinology, Metabolism, and Nutrition has received an award (1F32-DK116542-01A1) from the National Institutes of Health for a project entitled "The Role of Islet DPP4 for Regulation of Glucose Homeostasis." Total funding will be $178,866.

Matthew D. Hirschey of Endocrinology, Metabolism, and Nutrition has received an award (1R01-DK115568-01) from the National Institutes of Health for a project entitled "Post-Translational and Epigenetic Control of Branched-Chain Amino Acid Metabolism." Total funding will be $1,607,083.

L. Ebony Boulware of General Internal Medicine has received an award (1Ul1-TR002353-01) from the National Institutes of Health for a project entitled "Duke CTSA." Total funding will be $44,823,543.

David Edelman of General Internal Medicine has received an award (1TL1-TR002555-01) from the National Institutes of Health for a project entitled "Duke CTSA (TL1)." Total funding will be $3,402,439.

Anthony D. Sung of Hematologic Malignancies and Cellular Therapy has received an award from the Sloan Kettering Institute for a project entitled "MSKCC Microbiota." Total funding will be $49,999.

Emily Bailey (Mentor: Gregory Gray) of Infectious Diseases has received an award through East Carolina University for a project entitled "A Feasibility Study of Conducting Surveillance for Swine Pathogens in Swine Slurry." Total funding will be $5,000.

John A. Bartlett of Infectious Diseases has received an award (5D43-TW009595-06) from the National Institutes of Health for a project entitled "Sociobehavioral Sciences Research to Improve Care for HIV Infection in Tanzania." Total funding will be $1,473,135.

Myaing M. Nyunt of Infectious Diseases has received a sub-award (NNX17AI06G) through the University of Maryland for a project entitled "Understanding the Role of Land Cover/Land Use Nexus in Malaria Transmission under Changing Socio-Economic Climate in Myanmar." Total funding will be $127,479.

Wendy A. Prudhomme - O'Meara of Infectious Diseases has received an award from the Bill and Melinda Gates Foundation for a project entitled "Webuye Education and Research Laboratory (WERL)." Total funding will be $55,000.

Michael A. Hauser of Medical Genetics has received a sub-award (1U54-HG009826-01) through the University of Ibadan for a project entitled "Eyes of Africa: The Genetics of Blindness." Total funding will be $121,654.

Brent A. Hanks of Medical Oncology has received an award from the Agency for Science, Technology and Research for a project entitled "Investigating the Combination PORCN Inhibitor, ETC-159, and Checkpoint Inhibitor Immunotherapy in Pre-Clinical Cancer Models." Total funding will be $118,514.

P. Kelly Marcom of Medical Oncology has received a sub-award (2003472370) through Johns Hopkins University for a project entitled "Translational Breast Cancer Research Consortium-2017 Komen Foundation SGK." Total funding will be $50,000.

Laura P. Svetkey of Nephrology has received an award (1KL2-TR002554-01) from the National Institutes of Health for a project entitled "Duke CTSA (KL2)." Total funding will be $8,202,150.

Neil R. MacIntyre of Pulmonary, Allergy, and Critical Care Medicine has received an award from the Respiratory Compromise Institute for a project entitled "Respiratory Compromise & Unplanned Intubations." Total funding will be $88,308.

Loretta Que of Pulmonary, Allergy, and Critical Care Medicine has received a sub-award through the American Lung Association for a project entitled "Losartan Effects on Emphysema Progression (LEEP)."

Timothy Scialla of Pulmonary, Allergy, and Critical Care Medicine has received a sub-award (5U01-HL128954-03) through the COPD Foundation for a project entitled "Intervention Study In overweight patients with COPD (INSIGHT COPD) trial." Total funding will be $10,200.

Timothy Scialla of Pulmonary, Allergy, and Critical Care Medicine has received a sub-award (5U01-HL128954-03) through the COPD Foundation for a project entitled "Redifining Therapy in Early COPD (RETHINC) Trial." Total funding will be $29,800.

Industry-sponsored Clinical Trials

Adam D. Devore of Cardiology has received an award from the Novartis Pharmaceuticals Corporation for a project entitled "Patient Reported Outcomes Investigation Following Initiation of Drug Therapy with Entresto (Sacubitril/Valsartan) in Heart Failure." Total funding will be $36,851.

Christopher Granger of Cardiology has received an award from Boehringer Ingelheim Pharmaceuticals, Inc. for a project entitled "CV Outcome Trials for Diabetes Drugs: Think Tank." Total funding will be $15,000.

Sudarshan Rajagopal of Cardiology has received an award from Actelion Pharmaceuticals Ltd. for a project entitled "Opsummit Historical Users cohort study (OrPHeUS)." Total funding will be $102,410.

Sreekanth Vemulapalli of Cardiology has received an award from the Boston Scientific Corporation for a project entitled "Computational Fluid Dynamics for Peripheral Artery Disease." Total funding will be $90,001.

Andrew Wang of Cardiology has received an award from MyoKardia, Inc. for a project entitled "MAVERICK-HCM (MYK-461-006)." Total funding will be $113,757.

David D'Alessio of Endocrinology, Metabolism, and Nutrition has received an award from Eli Lilly and Company for a project entitled "Eli Lilly Research Program Agreement." Total funding will be $262,250.

Carl L. Berg of Gastroenterology has received an award from the Novartis Pharmaceuticals Corporation for a project entitled "Telesto." Total funding will be $994,939.

Danielle M. Brander of Hematologic Malignancies and Cellular Therapy has received an award from BeiGene, Ltd for a project entitled "BGB-3111-304 An International, Phase 3, Open-label, Randomized Study of BGB-3111 Compared with Bendamustine plus Rituximab in Patients with Previously Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma." Total funding will be $165,521.

David Rizzieri of Hematologic Malignancies and Cellular Therapy has received an award from Helsinn Healthcare S.A. for a project entitled "A Phase III Double-Blind, Placebo-Controlled, Multicenter, Randomized Study of Pracinostat in Combination with Azacitidine in Patients>= 18 years with Newly Diagnosed Acute Myeloid Leukemia unfit for Standard Induction Chemotherapy.." Total funding will be $179,047.

David Rizzieri of Hematologic Malignancies and Cellular Therapy has received an award from Astellas Pharma Inc. for a project entitled "A Multicenter, open-label treatment protocol of Gilteritinib (ASP2215) in patients with FMS-like Tyrosine Kinase 3 (FLT3) Mutated Relapsed or Refractory Acute Myeloid Leukemia (AMLJ) or FLT3-Mutated AML in Complete Remission (CR) with Mini ResiduaL." Total funding will be $145,055.

David Rizzieri of Hematologic Malignancies and Cellular Therapy has received an award from Nohla Therapeutics Inc., for a project entitled "A Phase 2 Open-Label, Multi-Center, Randomized, Controlled, Dose-Finding Study of DCC-UCB In Adults Receiving High Dose Chemotherapy For Acute Myleoid Leukemia." Total funding will be $257,938.

Nirmish R. Shah of Hematology has received an award from Global Blood Therapeutics, Inc. for a project entitled "An Open label extension study of GBT440 administered orally to patients with sickle cell disease who have participated in GBT440 clinical trials." Total funding will be $107,207.

Nirmish R. Shah of Hematology has received an award from the Novartis Pharmaceuticals Corporation for a project entitled "SUCCESSOR Chart Review." Total funding will be $13,454.

Myaing M. Nyunt of Infectious Diseases has received a sub-award (AID-482-A-16-00003) through the University Research Co., LLC for a project entitled "Defeat Malaria Initiative Myanmar." Total funding will be $520,673.

Megan A. McNamara of Medical Oncology has received an award from Seattle Genetics, Inc for a project entitled "A single-arm, open-label, multicenter study of enfortumab vedotin (ASG-22CE) for treatment of patients with locally advanced or metastatic urothelial cancer who previously received immune checkpoint I." Total funding will be $615,799.

John H. Strickler of Medical Oncology has received an award from AbbVie Inc. for a project entitled "Phase 2 Study Comparing Efficacy and Safety of ABT-165 plus FOLFIRI vs Bevacizumab plus FOLFIRI in Metastatic Colorectal Cancer Previously Treated with Fluoropyrimidine/Oxaliplatin and Bevacizumab." Total funding will be $1,016,063.

Neil R. MacIntyre of Pulmonary, Allergy, and Critical Care Medicine has received an award from ALung Technologies for a project entitled "Prospective trial to validate safety of Hemolung Respiratory Assist System for COPD patients." Total funding will be $742,222.

Kim M. Huffman of Rheumatology and Immunology has received an award from Flexion Therapeutics Inc. for a project entitled "FX006-2017-014." Total funding will be $308,773.

Ankoor Shah of Rheumatology and Immunology has received an award from Boehringer Ingelheim Pharmaceuticals, Inc. for a project entitled "A trial to evaluate the safety of long term treatment with nintedanib in patients with scleroderma related lung fibrosis." Total funding will be $147,526.

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