The new Duke Center for Personalized Medicine has announced a funding opportunity for multidisciplinary collaborative developmental projects that will explore personalized medicine topics in the context of Duke Medicine.
It is anticipated that two to three projects will be funded at a level of up to $50,000 per annum renewable for up to a total of two years based upon demonstrated progress within the first year, and pending the receipt of a reasonable number of responsive and appropriate proposals.
Personalized medicine is meant to be the application of proven medical interventions or therapies across the continuum of chronic medical conditions that are individualized to personal patient characteristics or preferences. Of particular interest are projects that incorporate individual patient profiling or risk stratification, that employ molecular profiling methods, and that work with established programs at the Duke Center for Living or Duke Primary Care at Pickett Road and Pickens Clinic, which are several of the “living laboratories” for Duke Personalized Medicine. An example would be the use of peripheral blood molecular profiling to identify individuals at high risk for medical complications from aggressive lipid lowering therapies for cardiovascular disease prevention.
The Center for Personalized Medicine Research group has been working toward outcomes at the patient, provider, practice, and health systems level and include clinical, personal, behavioral, economic and patient satisfaction outcomes.Preliminary proposals should include detail regarding:
- the specific question to be addressed;
- the application to personalized medicine;
- the collaborative multidisciplinary nature of the project with detail about the contributing researchers/groups; and
- the potential for long term sustainability and funding once the goals of the project are completed.
- Be carried out by a multidisciplinary team
- Utilize the learning laboratories of the CFL, Pickett or Pickens clinic
- Address the definition of personalized medicine that should be stated in the RFA: An integrated evidence-based approach to patient care across the continuum (from health to disease), using multidisciplinary teams to promote health and wellness, patient education, empowerment, and satisfaction, and to use the innovative tools to customize disease prevention, detection, and treatment
- Be designed with the intent of using generated pilot data for follow on funding and be explicit on what follow on funding will be sought.
- Should address some combination of molecular, behavioral and policy research questions.