Aimee Kirsch Zaas, MD

Professor of Medicine
Campus mail 2301 Erwin Rd, Box 3182, Durham, NC 27710
Phone (919) 681-1464
Email address aimee.zaas@duke.edu

Medical education
Genomic applications for diagnosis of infectious diseases
Genomic applications for prediction of infectious diseases

Education and Training

  • Fellow in Infectious Diseases, Medicine, Duke University, 2003 - 2004
  • Fellow in Infectious Diseases, Medicine, Duke University, 2001 - 2002
  • Medical Resident, Medicine, Johns Hopkins University, 1998 - 2001
  • M.D., Northwestern University, 1998

Publications

Chen, Bo, Minhua Chen, John Paisley, Aimee Zaas, Christopher Woods, Geoffrey S. Ginsburg, Alfred Hero, Joseph Lucas, David Dunson, and Lawrence Carin. “Bayesian inference of the number of factors in gene-expression analysis: application to human virus challenge studies.” Bmc Bioinformatics 11 (November 9, 2010): 552. https://doi.org/10.1186/1471-2105-11-552.

PMID
21062443
Full Text

Paisley, J., A. Zaas, C. W. Woods, G. S. Ginsburg, and L. Carin. “A stick-breaking construction of the beta process.” Icml 2010  Proceedings, 27th International Conference on Machine Learning, September 17, 2010, 847–54.

Scholars@Duke

Ahn, Sun-Hee, Hitesh Deshmukh, Nicole Johnson, Lindsay G. Cowell, Thomas H. Rude, William K. Scott, Charlotte L. Nelson, et al. “Two genes on A/J chromosome 18 are associated with susceptibility to Staphylococcus aureus infection by combined microarray and QTL analyses.” Plos Pathog 6, no. 9 (September 2, 2010): e1001088. https://doi.org/10.1371/journal.ppat.1001088.

PMID
20824097
Full Text

LaFayette, Shantelle L., Cathy Collins, Aimee K. Zaas, Wiley A. Schell, Marisol Betancourt-Quiroz, AA Leslie Gunatilaka, John R. Perfect, and Leah E. Cowen. “PKC signaling regulates drug resistance of the fungal pathogen Candida albicans via circuitry comprised of Mkc1, calcineurin, and Hsp90.” Plos Pathog 6, no. 8 (August 26, 2010): e1001069. https://doi.org/10.1371/journal.ppat.1001069.

PMID
20865172
Full Text

Pfeiffer, Christopher D., Guillermo Garcia-Effron, Aimee K. Zaas, John R. Perfect, David S. Perlin, and Barbara D. Alexander. “Breakthrough invasive candidiasis in patients on micafungin.” J Clin Microbiol 48, no. 7 (July 2010): 2373–80. https://doi.org/10.1128/JCM.02390-09.

PMID
20421445
Full Text

Zaas, Aimee K., Hamza Aziz, Joseph Lucas, John R. Perfect, and Geoffrey S. Ginsburg. “Blood gene expression signatures predict invasive candidiasis.” Sci Transl Med 2, no. 21 (March 3, 2010): 21ra17. https://doi.org/10.1126/scitranslmed.3000715.

PMID
20374997
Full Text

Zaas, A. K., M. Chen, A. O. Hero, J. Lucas, L. Carin, and G. S. Ginsburg. “Response: Improving Development of the Molecular Signature for Diagnosis of Acute Respiratory Viral Infections.” Cell Host and Microbe 7, no. 2 (February 18, 2010): 102. https://doi.org/10.1016/j.chom.2010.02.002.

Full Text

Zaas, Aimee K., Minhua Chen, Jay Varkey, Timothy Veldman, Alfred O. Hero, Joseph Lucas, Yongsheng Huang, et al. “Gene expression signatures diagnose influenza and other symptomatic respiratory viral infections in humans.” Cell Host Microbe 6, no. 3 (September 17, 2009): 207–17. https://doi.org/10.1016/j.chom.2009.07.006.

PMID
19664979
Full Text

Singh, Sheena D., Nicole Robbins, Aimee K. Zaas, Wiley A. Schell, John R. Perfect, and Leah E. Cowen. “Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin.” Plos Pathog 5, no. 7 (July 2009): e1000532. https://doi.org/10.1371/journal.ppat.1000532.

PMID
19649312
Full Text

Shapiro, Rebecca S., Priya Uppuluri, Aimee K. Zaas, Cathy Collins, Heather Senn, John R. Perfect, Joseph Heitman, and Leah E. Cowen. “Hsp90 orchestrates temperature-dependent Candida albicans morphogenesis via Ras1-PKA signaling.” Curr Biol 19, no. 8 (April 28, 2009): 621–29. https://doi.org/10.1016/j.cub.2009.03.017.

PMID
19327993
Full Text

Pages