Endocrinology, Metabolism, and Nutrition

Akshay Bareja, PhD

Assistant Professor of Medicine
Member of Duke Molecular Physiology Institute
Email address akshay.bareja@duke.edu

I am interested in developing approaches to derive biological insight from multi-omics and biological "big" data. My areas of interest include aging, stem cell biology, and cancer. I also have a strong interest in teaching and developing novel curricula, and am an active member of Duke's +Data Science and Center for Computational Thinking. 

Education and Training

  • D.Phil., University of Oxford (United Kingdom), 2011

Grants

Publications

Bareja, Akshay, James A. Draper, Lauren H. Katz, David E. Lee, Paul A. Grimsrud, and James P. White. “Chronic caloric restriction maintains a youthful phosphoproteome in aged skeletal muscle.” Mech Ageing Dev 195 (April 2021): 111443. https://doi.org/10.1016/j.mad.2021.111443.

PMID
33529682
Full Text

Huffman, Kim M., Brian J. Andonian, Dennis M. Abraham, Akshay Bareja, David E. Lee, Lauren H. Katz, Janet L. Huebner, William E. Kraus, and James P. White. “Exercise protects against cardiac and skeletal muscle dysfunction in a mouse model of inflammatory arthritis.” J Appl Physiol (1985) 130, no. 3 (March 1, 2021): 853–64. https://doi.org/10.1152/japplphysiol.00576.2020.

PMID
33411638
Full Text

Baht, Gurpreet S., Akshay Bareja, David E. Lee, Rajesh R. Rao, Rong Huang, Janet L. Huebner, David B. Bartlett, et al. “Author Correction: Meteorin-like facilitates skeletal muscle repair through a Stat3/IGF-1 mechanism.” Nature Metabolism 2, no. 8 (August 2020): 794. https://doi.org/10.1038/s42255-020-0257-y.

PMID
32694832
Full Text

Baht, Gurpreet S., Akshay Bareja, David E. Lee, Rajesh R. Rao, Rong Huang, Janet L. Huebner, David B. Bartlett, et al. “Meteorin-like facilitates skeletal muscle repair through a Stat3/IGF-1 mechanism.” Nat Metab 2, no. 3 (March 2020): 278–89. https://doi.org/10.1038/s42255-020-0184-y.

PMID
32694780
Full Text

Lee, David E., Akshay Bareja, David B. Bartlett, and James P. White. “Autophagy as a Therapeutic Target to Enhance Aged Muscle Regeneration.” Cells 8, no. 2 (February 20, 2019). https://doi.org/10.3390/cells8020183.

PMID
30791569
Full Text

Bareja, Akshay, Shubham Patel, Conrad P. Hodgkinson, Alan Payne, and Victor J. Dzau. “Understanding the mechanism of bias signaling of the insulin-like growth factor 1 receptor: Effects of LL37 and HASF.” Cell Signal 46 (June 2018): 113–19. https://doi.org/10.1016/j.cellsig.2018.02.013.

PMID
29499305
Full Text

Bareja, Akshay, Conrad P. Hodgkinson, Erik Soderblom, Greg Waitt, and Victor J. Dzau. “The proximity-labeling technique BioID identifies sorting nexin 6 as a member of the insulin-like growth factor 1 (IGF1)-IGF1 receptor pathway.” J Biol Chem 293, no. 17 (April 27, 2018): 6449–59. https://doi.org/10.1074/jbc.RA118.002406.

PMID
29530981
Full Text

Bareja, Akshay, Conrad P. Hodgkinson, Alan J. Payne, Richard E. Pratt, and Victor J. Dzau. “HASF (C3orf58) is a novel ligand of the insulin-like growth factor 1 receptor.” Biochem J 474, no. 5 (February 20, 2017): 771–80. https://doi.org/10.1042/BCJ20160976.

PMID
28096202
Full Text

Hodgkinson, Conrad P., Akshay Bareja, José A. Gomez, and Victor J. Dzau. “Emerging Concepts in Paracrine Mechanisms in Regenerative Cardiovascular Medicine and Biology.” Circ Res 118, no. 1 (January 8, 2016): 95–107. https://doi.org/10.1161/CIRCRESAHA.115.305373.

PMID
26837742
Full Text

Pages