Gastroenterology

Andrew Joseph Muir, MD

Professor of Medicine
Chief, Division of Gastroenterology in the Department of Medicine
Member in the Duke Clinical Research Institute
Campus mail 03137B Hosp South, Durham, NC 27710
Phone (919) 684-2052
Email address andrew.muir@duke.edu
  • Hepatitis C 
  • Primary sclerosing cholangitis
  • Cirrhosis
  • Liver Transplantation
  • Clinical Trials
  • Healthcare disparities in liver disease 
  • Outcomes Research

Education and Training

  • Fellow in Gastroenterology, Medicine, Duke University, 1998 - 2000
  • Chief Medical Resident, Medicine, Duke University, 1997 - 1998
  • Fellow in Gastroenterology, Medicine, Duke University, 1996 - 1997
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.H.S., Duke University, 2001
  • M.D., Duke University, 1993

Grants

Publications

Hirschfield, GM, Chazouillères, O, Drenth, JP, Thorburn, D, Harrison, SA, Landis, CS, Mayo, MJ, Muir, AJ, Trotter, JF, Leeming, DJ, Karsdal, MA, Jaros, MJ, Ling, L, Kim, KH, Rossi, SJ, Somaratne, RM, DePaoli, AM, and Beuers, U. "Effect of NGM282, an FGF19 analogue, in primary sclerosing cholangitis: A multicenter, randomized, double-blind, placebo-controlled phase II trial." Journal of Hepatology 70, no. 3 (March 2019): 483-493.

PMID
30414864
Full Text

Muir, AJ, Levy, C, Janssen, HLA, Montano-Loza, AJ, Shiffman, ML, Caldwell, S, Luketic, V, Ding, D, Jia, C, McColgan, BJ, McHutchison, JG, Mani Subramanian, G, Myers, RP, Manns, M, Chapman, R, Afdhal, NH, Goodman, Z, Eksteen, B, Bowlus, CL, and GS-US-321-0102 Investigators, . "Simtuzumab for Primary Sclerosing Cholangitis: Phase 2 Study Results With Insights on the Natural History of the Disease." Hepatology (Baltimore, Md.) 69, no. 2 (February 2019): 684-698.

PMID
30153359
Full Text

Younossi, Z, Stepanova, M, Sanyal, AJ, Harrison, SA, Ratziu, V, Abdelmalek, MF, Diehl, AM, Caldwell, S, Shiffman, ML, Schall, RA, McColgan, B, Subramanian, GM, Myers, RP, Muir, A, Afdhal, NH, Bosch, J, and Goodman, Z. "The conundrum of cryptogenic cirrhosis: Adverse outcomes without treatment options." Journal of Hepatology 69, no. 6 (December 2018): 1365-1370.

PMID
30144554
Full Text

Harrison, SA, Abdelmalek, MF, Caldwell, S, Shiffman, ML, Diehl, AM, Ghalib, R, Lawitz, EJ, Rockey, DC, Schall, RA, Jia, C, McColgan, BJ, McHutchison, JG, Subramanian, GM, Myers, RP, Younossi, Z, Ratziu, V, Muir, AJ, Afdhal, NH, Goodman, Z, Bosch, J, Sanyal, AJ, and GS-US-321-0105 and GS-US-321-0106 Investigators, . "Simtuzumab Is Ineffective for Patients With Bridging Fibrosis or Compensated Cirrhosis Caused by Nonalcoholic Steatohepatitis." Gastroenterology 155, no. 4 (October 2018): 1140-1153.

PMID
29990488
Full Text

Patel, YA, Henson, JB, Wilder, JM, Zheng, J, Chow, S-C, Berg, CL, Knechtle, SJ, and Muir, AJ. "The impact of human leukocyte antigen donor and recipient serotyping and matching on liver transplant graft failure in primary sclerosing cholangitis, autoimmune hepatitis, and primary biliary cholangitis." Clinical Transplantation 32, no. 10 (October 2018): e13388-null.

PMID
30136315
Full Text

Proeschold-Bell, RJ, Evon, DM, Makarushka, C, Wong, JB, Datta, SK, Yao, J, Patkar, AA, Mannelli, P, Hodge, T, Naggie, S, Wilder, JM, Fried, MW, Niedzwiecki, D, and Muir, AJ. "The Hepatitis C-Alcohol Reduction Treatment (Hep ART) intervention: Study protocol of a multi-center randomized controlled trial." Contemporary Clinical Trials 72 (September 2018): 73-85.

PMID
30006024
Full Text

Younossi, ZM, Afendy, A, Stepanova, M, Racila, A, Nader, F, Gomel, R, Safer, R, Lenderking, WR, Skalicky, A, Kleinman, L, Myers, RP, Subramanian, GM, McHutchison, JG, Levy, C, Bowlus, CL, Kowdley, K, and Muir, AJ. "Development and validation of a primary sclerosing cholangitis-specific patient-reported outcomes instrument: The PSC PRO." July 2018.

PMID
29152767
Full Text

Nitsche, B, Miller, SC, Giorgio, M, Berry, CA, and Muir, A. "Improving Hepatitis C Identification: Technology Alone Is Not the Answer." Health Promotion Practice 19, no. 4 (July 2018): 506-512.

PMID
28893101
Full Text

Patel, YA, and Muir, AJ. "Editorial: platelet transfusions in cirrhosis-do the risks outweigh the unclear benefits?." Alimentary Pharmacology & Therapeutics 47, no. 11 (June 2018): 1553-1554.

PMID
29878440
Full Text

Wilder, JM, and Muir, A. "Direct acting antivirals for the treatment of hepatitis C in ethnic minority populations." Expert Opinion on Pharmacotherapy 19, no. 5 (April 2018): 451-456. (Review)

PMID
29488438
Full Text

Pages