Andrew Joseph Muir, MD

Professor of Medicine
Chief, Division of Gastroenterology in the Department of Medicine
Member in the Duke Clinical Research Institute
Campus mail 03137B Hosp South, Durham, NC 27710
Phone (919) 684-2052
Email address
  • Hepatitis C 
  • Primary sclerosing cholangitis
  • Cirrhosis
  • Liver Transplantation
  • Clinical Trials
  • Healthcare disparities in liver disease 
  • Outcomes Research
In Their Words

Education and Training

  • Fellow in Gastroenterology, Medicine, Duke University, 1998 - 2000
  • Chief Medical Resident, Medicine, Duke University, 1997 - 1998
  • Fellow in Gastroenterology, Medicine, Duke University, 1996 - 1997
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.H.S., Duke University, 2001
  • M.D., Duke University, 1993


Clark, PJ, Thompson, AJ, Patel, K, Muir, AJ, and Volk, ML. "Trends in hepatitis C treatment uptake in the United States." Hepatology 60, no. 2 (August 2014): 768-769.

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Charlton, M, Samuel, D, Gane, E, Jr, BRS, Curry, MP, Kwo, P, Fontana, R, Gilroy, R, Teperman, L, Muir, AJ, McHutchison, JG, Symonds, WT, Denning, J, McNair, L, Arterburn, S, Terrault, N, Forns, X, and Manns, MP. "Sofosbuvir and Ribavirin for the Treatment of Recurrent Hepatitis C Infection after Liver Transplantation: Results of a Prospective, Multicenter Study." June 2014.


Muir, AJ. "The rapid evolution of treatment strategies for hepatitis C." The American Journal of Gastroenterology 109, no. 5 (May 2014): 628-636. (Review)

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Afdhal, N, Zeuzem, S, Kwo, P, Chojkier, M, Gitlin, N, Puoti, M, Romero-Gomez, M, Zarski, J-P, Agarwal, K, Buggisch, P, Foster, GR, Bräu, N, Buti, M, Jacobson, IM, Subramanian, GM, Ding, X, Mo, H, Yang, JC, Pang, PS, Symonds, WT, McHutchison, JG, Muir, AJ, Mangia, A, Marcellin, P, and ION-1 Investigators, . "Ledipasvir and sofosbuvir for untreated HCV genotype 1 infection." The New England Journal of Medicine 370, no. 20 (May 2014): 1889-1898.

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Moylan, CA, Owzar, K, Muir, AJ, Cauchy, F, Belghiti, J, Diehl, AM, and Paradis, V. "Gene Expression and Pathway Analyses Reveal Distinctions Between Hepatocellular Carcinoma Arising in Fibrotic and Non-Fibrotic Nonalcoholic Fatty Liver Disease." May 2014.


Kowdley, KV, Gordon, SC, Reddy, KR, Rossaro, L, Bernstein, DE, Lawitz, E, Shiffman, ML, Schiff, E, Ghalib, R, Ryan, M, Rustgi, V, Chojkier, M, Herring, R, Di Bisceglie, AM, Pockros, PJ, Subramanian, GM, An, D, Svarovskaia, E, Hyland, RH, Pang, PS, Symonds, WT, McHutchison, JG, Muir, AJ, Pound, D, Fried, MW, and ION-3 Investigators, . "Ledipasvir and sofosbuvir for 8 or 12 weeks for chronic HCV without cirrhosis." The New England Journal of Medicine 370, no. 20 (May 2014): 1879-1888.

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Afdhal, N, Reddy, KR, Nelson, DR, Lawitz, E, Gordon, SC, Schiff, E, Nahass, R, Ghalib, R, Gitlin, N, Herring, R, Lalezari, J, Younes, ZH, Pockros, PJ, Di Bisceglie, AM, Arora, S, Subramanian, GM, Zhu, Y, Dvory-Sobol, H, Yang, JC, Pang, PS, Symonds, WT, McHutchison, JG, Muir, AJ, Sulkowski, M, Kwo, P, and ION-2 Investigators, . "Ledipasvir and sofosbuvir for previously treated HCV genotype 1 infection." The New England Journal of Medicine 370, no. 16 (April 11, 2014): 1483-1493.

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Vierling, JM, Davis, M, Flamm, S, Gordon, SC, Lawitz, E, Yoshida, EM, Galati, J, Luketic, V, McCone, J, Jacobson, I, Marcellin, P, Muir, AJ, Poordad, F, Pedicone, LD, Albrecht, J, Brass, C, Howe, AYM, Colvard, LY, Helmond, FA, Deng, W, Treitel, M, Wahl, J, and Bronowicki, J-P. "Boceprevir for chronic HCV genotype 1 infection in patients with prior treatment failure to peginterferon/ribavirin, including prior null response." J Hepatol 60, no. 4 (April 2014): 748-756.

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Melia, MT, Bräu, N, Poordad, F, Lawitz, EJ, Shiffman, ML, McHutchison, JG, Muir, AJ, Galler, GW, Nyberg, LM, Lee, WM, Schiff, E, Long, J, Noviello, S, Brass, CA, Pedicone, LD, and Sulkowski, MS. "Infections during peginterferon/ribavirin therapy are associated with the magnitude of decline in absolute lymphocyte count: results of the IDEAL study." Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 58, no. 7 (April 2014): 960-969.

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Muir, AJ, Gong, L, Johnson, SG, Lee, MTM, Williams, MS, Klein, TE, Caudle, KE, and Nelson, DR. "Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for IFNL3 (IL28B) Genotype and PEG Interferon-α–Based Regimens." Clinical Pharmacology & Therapeutics 95, no. 2 (February 2014): 141-146.

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