Christopher Michael O'Connor, MD

Adjunct Professor in the Department of Medicine
Richard Sean Stack, M.D. Distinguished Professor
Campus mail 7401 Hosp North, Durham, NC 27710
Phone (919) 681-6195
Email address oconn002@mc.duke.edu

Dr. O’Connor’s research interests include: acute heart failure; co-morbidities in heart failure; clinical trials; biomarkers; and novel pharmacological and non-pharmacological approaches for the treatment of heart failure.

Education and Training

  • Fellow in Cardiology, Medicine, Duke University, 1988 - 1989
  • Chief Medical Resident - VAMC, Medicine, Duke University, 1987 - 1988
  • Cardiology Fellow, Medicine, Duke University, 1986 - 1987
  • Medical Resident, Medicine, Duke University, 1983 - 1986
  • M.D., University of Maryland, College Park, 1983

Grants

Publications

Psotka, Mitchell A., Federica Latta, Dario Cani, Mona Fiuzat, Marco Sbolli, Scott Barnett, Marco Metra, and Christopher M. O’Connor. “Publication Rates of Heart Failure Clinical Trials Remain Low.” J Am Coll Cardiol 75, no. 25 (June 30, 2020): 3151–61. https://doi.org/10.1016/j.jacc.2020.04.068.

PMID
32586589
Full Text

Bhatt, Ankeet S., Andrew P. Ambrosy, Allison Dunning, Adam D. DeVore, Javed Butler, Shelby Reed, Adriaan Voors, et al. “The burden of non-cardiac comorbidities and association with clinical outcomes in an acute heart failure trial - insights from ASCEND-HF.” Eur J Heart Fail 22, no. 6 (June 2020): 1022–31. https://doi.org/10.1002/ejhf.1795.

PMID
32212297
Full Text

Fiuzat, Mona, Naomi Lowy, Norman Stockbridge, Marco Sbolli, Federica Latta, JoAnn Lindenfeld, Eldrin F. Lewis, et al. “Endpoints in Heart Failure Drug Development: History and Future.” Jacc Heart Fail 8, no. 6 (June 2020): 429–40. https://doi.org/10.1016/j.jchf.2019.12.011.

PMID
32278679
Full Text

Damluji, Abdulla A., Gregory Rodriguez, Thomas Noel, Lakerria Davis, Vishal Dahya, Behnam Tehrani, Kelly Epps, et al. “Sarcopenia and health-related quality of life in older adults after transcatheter aortic valve replacement.” Am Heart J 224 (June 2020): 171–81. https://doi.org/10.1016/j.ahj.2020.03.021.

PMID
32416332
Full Text

Sbolli, Marco, Mona Fiuzat, Dario Cani, and Christopher M. O’Connor. “Depression and heart failure: the lonely comorbidity.” Eur J Heart Fail, May 29, 2020. https://doi.org/10.1002/ejhf.1865.

PMID
32468714
Full Text

Armstrong, Paul W., Burkert Pieske, Kevin J. Anstrom, Justin Ezekowitz, Adrian F. Hernandez, Javed Butler, Carolyn S. P. Lam, et al. “Vericiguat in Patients with Heart Failure and Reduced Ejection Fraction.” N Engl J Med 382, no. 20 (May 14, 2020): 1883–93. https://doi.org/10.1056/NEJMoa1915928.

PMID
32222134
Full Text

Reddy, Yogesh N. V., Barry A. Borlaug, Christopher M. O’Connor, and Bernard J. Gersh. “Novel approaches to the management of chronic systolic heart failure: future directions and unanswered questions.” Eur Heart J 41, no. 18 (May 7, 2020): 1764–74. https://doi.org/10.1093/eurheartj/ehz364.

PMID
31199474
Full Text

Butler, Javed, Muhammad Shahzeb Khan, Stefan D. Anker, Gregg C. Fonarow, Raymond J. Kim, Savina Nodari, Christopher M. O’Connor, et al. “Effects of Elamipretide on Left Ventricular Function in Patients With Heart Failure With Reduced Ejection Fraction: The PROGRESS-HF Phase 2 Trial.” J Card Fail 26, no. 5 (May 2020): 429–37. https://doi.org/10.1016/j.cardfail.2020.02.001.

PMID
32068002
Full Text

Pages