Christopher Michael O'Connor, MD

Adjunct Professor in the Department of Medicine
Richard Sean Stack, M.D. / Guidant Foundation Professor of Cardiology
Campus mail 7401 Hosp North, Durham, NC 27710
Phone (919) 681-6195
Email address

Dr. O’Connor’s research interests include: acute heart failure; co-morbidities in heart failure; clinical trials; biomarkers; and novel pharmacological and non-pharmacological approaches for the treatment of heart failure.

Education and Training

  • Fellow in Cardiology, Medicine, Duke University, 1988 - 1989
  • Chief Medical Resident - VAMC, Medicine, Duke University, 1987 - 1988
  • Cardiology Fellow, Medicine, Duke University, 1986 - 1987
  • Medical Resident, Medicine, Duke University, 1983 - 1986
  • M.D., University of Maryland, College Park, 1983


Warraich, Haider J., Christopher M. O’Connor, Hongqiu Yang, Bradi B. Granger, Kimberly S. Johnson, Daniel B. Mark, Kevin J. Anstrom, et al. “African Americans With Advanced Heart Failure Are More Likely to Die in a Health Care Facility Than at Home or in Hospice: An Analysis From the PAL-HF Trial..” J Card Fail 25, no. 8 (August 2019): 693–94.

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Tehrani, B. N., and C. M. O’Connor. “Reply: Standardized and Tailored Approach to Therapies for Cardiogenic Shock.” Journal of the American College of Cardiology 74, no. 4 (July 30, 2019): 593–94.

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O’Connor, Christopher, Mona Fiuzat, Hillary Mulder, Adrian Coles, Tariq Ahmad, Justin A. Ezekowitz, Kirkwood F. Adams, et al. “Clinical factors related to morbidity and mortality in high-risk heart failure patients: the GUIDE-IT predictive model and risk score..” Eur J Heart Fail 21, no. 6 (June 2019): 770–78.

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Russell, Frances M., Robert R. Ehrman, Robinson Ferre, Luna Gargani, Vicki Noble, Jordan Rupp, Sean P. Collins, et al. “Design and rationale of the B-lines lung ultrasound guided emergency department management of acute heart failure (BLUSHED-AHF) pilot trial..” Heart Lung 48, no. 3 (May 2019): 186–92.

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Psotka, Mitchell A., Susan E. Ammon, Mona Fiuzat, Biykem Bozkurt, Eugene S. Chung, Robert T. Cole, Stephen J. Greene, et al. “Heart Failure Site-Based Research in the United States: Results of the Heart Failure Society of America Research Network Survey..” Jacc Heart Fail 7, no. 5 (May 2019): 431–38.

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Butler, Javed, Carolyn S. P. Lam, Kevin J. Anstrom, Justin Ezekowitz, Adrian F. Hernandez, Christopher M. O’Connor, Burkert Pieske, et al. “Rationale and Design of the VITALITY-HFpEF Trial..” Circ Heart Fail 12, no. 5 (May 2019).

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