Connie Watkins Bales, PhD

Professor in Medicine
Senior Fellow in the Center for the Study of Aging and Human Development
Campus mail 2508 Busse Bldg, Durham, NC 27710
Phone (919) 660-7519
Email address bales001@mc.duke.edu

Research in our laboratory focuses on the role of nutrition (particularly vitamins and minerals) in the prevention and management of chronic diseases in older adults. Previous studies have concerned trace elements and cardiovascular disease, calcium and osteoporosis, and renal synthesis of vitamin D as it relates to bone health. Some of our newest work emphasizes the role of micronutrients as antioxidants and their interaction with the aging process. We are also working on various aspects of energy balance in older adults, ranging from failure to thrive in stroke patients with dysphagia to exercise and nutrition effects in overweight subjects who begin physical training. Thus we have a number of clinical and epidemiological projects on-going, many of which include a strong emphasis on nutrition assessment techniques in middle-aged and elderly subjects.

Education and Training

  • Ph.D., University of Tennessee at Knoxville, 1981

Publications

Porter Starr, KN, Pieper, CF, Orenduff, MC, McDonald, SR, McClure, LB, Zhou, R, Payne, ME, and Bales, CW. "Improved Function With Enhanced Protein Intake per Meal: A Pilot Study of Weight Reduction in Frail, Obese Older Adults." The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 71, no. 10 (October 2016): 1369-1375.

PMID
26786203
Full Text

Slentz, CA, Bateman, LA, Willis, LH, Granville, EO, Piner, LW, Samsa, GP, Setji, TL, Muehlbauer, MJ, Huffman, KM, Bales, CW, and Kraus, WE. "Effects of exercise training alone vs a combined exercise and nutritional lifestyle intervention on glucose homeostasis in prediabetic individuals: a randomised controlled trial." Diabetologia 59, no. 10 (October 2016): 2088-2098.

PMID
27421729
Full Text

Starr, KNP, Pieper, CF, Orenduff, MC, McDonald, SR, McClure, LB, Zhou, R, Payne, ME, and Bales, CW. "Improved Function With Enhanced Protein Intake per Meal: A Pilot Study of Weight Reduction in Frail, Obese Older Adults." JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES 71, no. 10 (October 2016): 1369-1375.

Full Text

Porter Starr, KN, McDonald, SR, Weidner, JA, and Bales, CW. "Challenges in the Management of Geriatric Obesity in High Risk Populations." Nutrients 8, no. 5 (May 4, 2016). (Review)

PMID
27153084
Full Text

Bales, CW, Young, KR, and Anderson, JJB. "Nutrition and bone health in older adults." In Diet, Nutrients, and Bone Health, 413-430. April 19, 2016.

Scholars@Duke

Villareal, DT, Fontana, L, Das, SK, Redman, L, Smith, SR, Saltzman, E, Bales, C, Rochon, J, Pieper, C, Huang, M, Lewis, M, Schwartz, AV, and CALERIE Study Group, . "Effect of Two-Year Caloric Restriction on Bone Metabolism and Bone Mineral Density in Non-Obese Younger Adults: A Randomized Clinical Trial." Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research 31, no. 1 (January 2016): 40-51.

PMID
26332798
Full Text

"FIDELITY TO TREATMENT: IMPLEMENTING AN EXPERIMENTAL COMPARISON OF DEMENTIA HAND FEEDING TECHNIQUES." The Gerontologist 55, no. Suppl_2 (November 2015): 85-85.

Full Text

"IMPACT OF DIET-INDUCED WEIGHT LOSS ON PHYSICAL FUNCTION IN FRAIL, OBESE OLDER ADULTS." The Gerontologist 55, no. Suppl_2 (November 2015): 292-292.

Full Text

Glynn, EL, Piner, LW, Huffman, KM, Slentz, CA, Elliot-Penry, L, AbouAssi, H, White, PJ, Bain, JR, Muehlbauer, MJ, Ilkayeva, OR, Stevens, RD, Porter Starr, KN, Bales, CW, Volpi, E, Brosnan, MJ, Trimmer, JK, Rolph, TP, Newgard, CB, and Kraus, WE. "Impact of combined resistance and aerobic exercise training on branched-chain amino acid turnover, glycine metabolism and insulin sensitivity in overweight humans." Diabetologia 58, no. 10 (October 2015): 2324-2335.

PMID
26254576
Full Text

Yates, T, Davies, MJ, Haffner, SM, Schulte, PJ, Thomas, L, Huffman, KM, Bales, CW, Preiss, D, Califf, RM, Holman, RR, McMurray, JJV, Bethel, MA, Tuomilehto, J, and Kraus, WE. "Physical activity as a determinant of fasting and 2-h post-challenge glucose: a prospective cohort analysis of the NAVIGATOR trial." Diabetic Medicine : a Journal of the British Diabetic Association 32, no. 8 (August 2015): 1090-1096.

PMID
25818859
Full Text

Pages