Cristina Gasparetto, MD

Professor of Medicine
Member of the Duke Cancer Institute
Campus mail 2400 Pratt St Suite 5000, DUMC Box 3961, Durham, NC 27710
Phone (919) 668-1000
Email address gaspa001@mc.duke.edu

Dr. Gasparetto performs both laboratory and clinical research in the field of multiple myeloma. Her primary research interests are in developing immunotherapy approaches to treating multiple myeloma particularly in conjunction with hematopoietic stem cell transplantation. Ongoing laboratory research projects include the development of dendritic cell vaccines and antibody therapies. Clinical studies include a recently approved trial involving vaccination with autologous dendritic cells pulsed with idiotypic protein following high dose chemotherapy and autologous peripheral blood stem cells transplant. Upcoming trials include novel antibody therapies for multiple myeloma. Dr. Gasparetto is also an investigator on several other clinical trials for myeloma including non-myeloablative allogeneic transplantation, high dose sequential chemotherapy and autologous peripheral blood stem cell transplantation and transplantation of partially HLA matched unrelated cord blood.

Education and Training

  • Fellow in Hematology/Oncology, Medicine, Duke University, 1996 - 1999
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.D., Sapienza University of Rome (Italy), 1986

Grants

Publications

Islam, Prioty, Helen Tang, Haesu Jin, Felicia Cao, Lauren M. Bohannon, Yi Ren, Nelson J. Chao, et al. “Female Sex Is Associated with Improved Long-Term Survival Following Allogeneic Hematopoietic Stem Cell Transplantation.” Transplant Cell Ther 27, no. 9 (September 2021): 784.e1-784.e7. https://doi.org/10.1016/j.jtct.2021.06.012.

PMID
34146734
Full Text

Bohannon, Lauren, Helen Tang, Kristin Page, Yi Ren, Sin-Ho Jung, Alexandra Artica, Anne Britt, et al. “Decreased Mortality in 1-Year Survivors of Umbilical Cord Blood Transplant vs. Matched Related or Matched Unrelated Donor Transplant in Patients with Hematologic Malignancies.” Transplant Cell Ther 27, no. 8 (August 2021): 669.e1-669.e8. https://doi.org/10.1016/j.jtct.2021.05.002.

PMID
33991725
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Mo, Clifton C., Sundar Jagannath, Ajai Chari, Ajay K. Nooka, Sagar Lonial, David Siegel, Noa Biran, Cristina Gasparetto, Nizar J. Bahlis, and Paul Richardson. “Selinexor for the treatment of patients with previously treated multiple myeloma.” Expert Rev Hematol 14, no. 8 (August 2021): 697–706. https://doi.org/10.1080/17474086.2021.1923473.

PMID
33985401
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Pabon, Cindy M., Zhiguo Li, Therese Hennig, Carlos de Castro, Jadee L. Neff, Mitchell E. Horwitz, Thomas W. LeBlanc, et al. “Morphologic leukemia-free state in acute myeloid leukemia is sufficient for successful allogeneic hematopoietic stem cell transplant.” Blood Cancer J 11, no. 5 (May 16, 2021): 92. https://doi.org/10.1038/s41408-021-00481-9.

PMID
33994546
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Mikhael, Joseph, Karim Belhadj-Merzoug, Cyrille Hulin, Laure Vincent, Philippe Moreau, Cristina Gasparetto, Ludek Pour, et al. “A phase 2 study of isatuximab monotherapy in patients with multiple myeloma who are refractory to daratumumab.” Blood Cancer J 11, no. 5 (May 12, 2021): 89. https://doi.org/10.1038/s41408-021-00478-4.

PMID
33980831
Full Text

Kaufman, Jonathan L., Cristina Gasparetto, Fredrik H. Schjesvold, Philippe Moreau, Cyrille Touzeau, Thierry Facon, Lawrence H. Boise, et al. “Targeting BCL-2 with venetoclax and dexamethasone in patients with relapsed/refractory t(11;14) multiple myeloma.” Am J Hematol 96, no. 4 (April 1, 2021): 418–27. https://doi.org/10.1002/ajh.26083.

PMID
33368455
Full Text

Abonour, Rafat, Robert M. Rifkin, Cristina Gasparetto, Kathleen Toomey, Brian G. M. Durie, James W. Hardin, Howard R. Terebelo, et al. “Effect of initial treatment on health-related quality of life in patients with newly diagnosed multiple myeloma without immediate stem cell transplant intent: results from the Connect® MM Registry.” Br J Haematol 193, no. 1 (April 2021): 93–100. https://doi.org/10.1111/bjh.17131.

PMID
33118614
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Dimopoulos, Meletios, Sara Bringhen, Pekka Anttila, Marcelo Capra, Michele Cavo, Craig Cole, Cristina Gasparetto, et al. “Isatuximab as monotherapy and combined with dexamethasone in patients with relapsed/refractory multiple myeloma.” Blood 137, no. 9 (March 4, 2021): 1154–65. https://doi.org/10.1182/blood.2020008209.

PMID
33080623
Full Text

Giri, Vinay K., Kristin G. Kegerreis, Yi Ren, Lauren M. Bohannon, Erica Lobaugh-Jin, Julia A. Messina, Anita Matthews, et al. “Chlorhexidine Gluconate Bathing Reduces the Incidence of Bloodstream Infections in Adults Undergoing Inpatient Hematopoietic Cell Transplantation.” Transplant Cell Ther 27, no. 3 (March 2021): 262.e1-262.e11. https://doi.org/10.1016/j.jtct.2021.01.004.

PMID
33781532
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Racioppi, Alessandro, Tara Dalton, Sendhilnathan Ramalingam, Kristi Romero, Yi Ren, Lauren Bohannon, Consuelo Arellano, et al. “Assessing the Feasibility of a Novel mHealth App in Hematopoietic Stem Cell Transplant Patients.” Transplant Cell Ther 27, no. 2 (February 2021): 181.e1-181.e9. https://doi.org/10.1016/j.jtct.2020.10.017.

PMID
33830035
Full Text

Pages