Cristina Gasparetto, MD

Professor of Medicine
Member of the Duke Cancer Institute
Campus mail 2400 Pratt St Suite 5000, DUMC Box 3961, Durham, NC 27710
Phone (919) 668-1000
Email address gaspa001@mc.duke.edu

Dr. Gasparetto performs both laboratory and clinical research in the field of multiple myeloma. Her primary research interests are in developing immunotherapy approaches to treating multiple myeloma particularly in conjunction with hematopoietic stem cell transplantation. Ongoing laboratory research projects include the development of dendritic cell vaccines and antibody therapies. Clinical studies include a recently approved trial involving vaccination with autologous dendritic cells pulsed with idiotypic protein following high dose chemotherapy and autologous peripheral blood stem cells transplant. Upcoming trials include novel antibody therapies for multiple myeloma. Dr. Gasparetto is also an investigator on several other clinical trials for myeloma including non-myeloablative allogeneic transplantation, high dose sequential chemotherapy and autologous peripheral blood stem cell transplantation and transplantation of partially HLA matched unrelated cord blood.

Education and Training

  • Fellow in Hematology/Oncology, Medicine, Duke University, 1996 - 1999
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.D., Sapienza University of Rome (Italy), 1986

Grants

Publications

Pabon, Cindy M., Zhiguo Li, Therese Hennig, Carlos de Castro, Jadee L. Neff, Mitchell E. Horwitz, Thomas W. LeBlanc, et al. “Morphologic leukemia-free state in acute myeloid leukemia is sufficient for successful allogeneic hematopoietic stem cell transplant.” Blood Cancer J 11, no. 5 (May 16, 2021): 92. https://doi.org/10.1038/s41408-021-00481-9.

PMID
33994546
Full Text

Abonour, Rafat, Robert M. Rifkin, Cristina Gasparetto, Kathleen Toomey, Brian G. M. Durie, James W. Hardin, Howard R. Terebelo, et al. “Effect of initial treatment on health-related quality of life in patients with newly diagnosed multiple myeloma without immediate stem cell transplant intent: results from the Connect® MM Registry.” Br J Haematol 193, no. 1 (April 2021): 93–100. https://doi.org/10.1111/bjh.17131.

PMID
33118614
Full Text

Giri, Vinay K., Kristin G. Kegerreis, Yi Ren, Lauren M. Bohannon, Erica Lobaugh-Jin, Julia A. Messina, Anita Matthews, et al. “Chlorhexidine Gluconate Bathing Reduces the Incidence of Bloodstream Infections in Adults Undergoing Inpatient Hematopoietic Cell Transplantation.” Transplant Cell Ther 27, no. 3 (March 2021): 262.e1-262.e11. https://doi.org/10.1016/j.jtct.2021.01.004.

PMID
33781532
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Racioppi, Alessandro, Tara Dalton, Sendhilnathan Ramalingam, Kristi Romero, Yi Ren, Lauren Bohannon, Consuelo Arellano, et al. “Assessing the Feasibility of a Novel mHealth App in Hematopoietic Stem Cell Transplant Patients.” Transplant Cell Ther 27, no. 2 (February 2021): 181.e1-181.e9. https://doi.org/10.1016/j.jtct.2020.10.017.

PMID
33830035
Full Text

Maung, Ko K., Benny J. Chen, Ian Barak, Zhiguo Li, David A. Rizzieri, Cristina Gasparetto, Keith M. Sullivan, et al. “Phase I dose escalation study of naive T-cell depleted donor lymphocyte infusion following allogeneic stem cell transplantation.” Bone Marrow Transplant 56, no. 1 (January 2021): 137–43. https://doi.org/10.1038/s41409-020-0991-5.

PMID
32624583
Full Text

Smith, Patrick, Jillian C. Thompson, Elena Perea, Brian Wasserman, Lauren Bohannon, Alessandro Racioppi, Taewoong Choi, et al. “Clinical and Neuroimaging Correlates of Post-Transplant Delirium.” Biol Blood Marrow Transplant 26, no. 12 (December 2020): 2323–28. https://doi.org/10.1016/j.bbmt.2020.09.016.

PMID
32961373
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Ailawadhi, Sikander, Sundar Jagannath, Hans C. Lee, Mohit Narang, Robert M. Rifkin, Howard R. Terebelo, Brian G. M. Durie, et al. “Association between race and treatment patterns and survival outcomes in multiple myeloma: A Connect MM Registry analysis.” Cancer 126, no. 19 (October 1, 2020): 4332–40. https://doi.org/10.1002/cncr.33089.

PMID
32706404
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Gavriatopoulou, Maria, Ajai Chari, Christine Chen, Nizar Bahlis, Dan T. Vogl, Andrzej Jakubowiak, David Dingli, et al. “Integrated safety profile of selinexor in multiple myeloma: experience from 437 patients enrolled in clinical trials.” Leukemia 34, no. 9 (September 2020): 2430–40. https://doi.org/10.1038/s41375-020-0756-6.

PMID
32094461
Full Text

Chari, Ajai, Robert F. Cornell, Cristina Gasparetto, Chatchada Karanes, Jeffrey V. Matous, Ruben Niesvizky, Matthew Lunning, et al. “Final analysis of a phase 1/2b study of ibrutinib combined with carfilzomib/dexamethasone in patients with relapsed/refractory multiple myeloma.” Hematol Oncol 38, no. 3 (August 2020): 353–62. https://doi.org/10.1002/hon.2723.

PMID
32053229
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Jagannath, Sundar, Robert M. Rifkin, Cristina J. Gasparetto, Kathleen Toomey, Brian G. M. Durie, James W. Hardin, Howard R. Terebelo, et al. “Treatment Journeys of Patients With Newly Diagnosed Multiple Myeloma (NDMM): Results From The Connect MM Registry.” Clin Lymphoma Myeloma Leuk 20, no. 5 (May 2020): 272–76. https://doi.org/10.1016/j.clml.2019.10.002.

PMID
32144027
Full Text

Pages