Cristina Gasparetto, MD

Associate Professor of Medicine
Member of the Duke Cancer Institute
Campus mail 9058 North Pavilion, Durham, NC 27710
Phone (919) 668-1017
Email address gaspa001@mc.duke.edu

Dr. Gasparetto performs both laboratory and clinical research in the field of multiple myeloma. Her primary research interests are in developing immunotherapy approaches to treating multiple myeloma particularly in conjunction with hematopoietic stem cell transplantation. Ongoing laboratory research projects include the development of dendritic cell vaccines and antibody therapies. Clinical studies include a recently approved trial involving vaccination with autologous dendritic cells pulsed with idiotypic protein following high dose chemotherapy and autologous peripheral blood stem cells transplant. Upcoming trials include novel antibody therapies for multiple myeloma. Dr. Gasparetto is also an investigator on several other clinical trials for myeloma including non-myeloablative allogeneic transplantation, high dose sequential chemotherapy and autologous peripheral blood stem cell transplantation and transplantation of partially HLA matched unrelated cord blood.

In Their Words

Education and Training

  • Fellow in Hematology/Oncology, Medicine, Duke University, 1996 - 1999
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.D., Sapienza University of Rome (Italy), 1986

Publications

Sivaraj, D, Bacon, W, Long, GD, Rizzieri, DA, Horwitz, ME, Sullivan, KM, Kang, Y, Li, Z, Chao, NJ, and Gasparetto, C. "High-dose BCNU/Melphalan conditioning regimen before autologous stem cell transplantation in newly diagnosed multiple myeloma." Bone marrow transplantation 53, no. 1 (January 2018): 34-38.

PMID
29084203
Full Text

Huang, L-W, Bacon, W, Cirrincione, C, Peterson, B, Long, G, Rizzieri, D, Sullivan, KM, Corbet, K, Horwitz, M, Chao, N, Gasparetto, C, and Tuchman, SA. "Efficacy and safety of high-dose chemotherapy with autologous stem cell transplantation in senior versus younger adults with newly diagnosed multiple myeloma." Hematological oncology 35, no. 4 (December 2017): 752-759.

PMID
28105753
Full Text

Anand, S, Thomas, S, Corbet, K, Gasparetto, C, Long, GD, Lopez, R, Morris, AK, Rizzieri, DA, Sullivan, KM, Sung, AD, Sarantopoulos, S, Chao, NJ, and Horwitz, ME. "Adult Umbilical Cord Blood Transplantation Using Myeloablative Thiotepa, Total Body Irradiation, and Fludarabine Conditioning." November 2017.

PMID
28729147
Full Text

Htut, M, D'Souza, A, Krishnan, A, Bruno, B, Zhang, M-J, Fei, M, Diaz, MA, Copelan, E, Ganguly, S, Hamadani, M, Kharfan-Dabaja, M, Lazarus, H, Lee, C, Meehan, K, Nishihori, T, Saad, A, Seo, S, Ramanathan, M, Usmani, SZ, Gasparetto, C, Mark, TM, Nieto, Y, and Hari, P. "Autologous/Allogeneic Hematopoietic Cell Transplantation (HCT) Versus Tandem Autologous Transplantation for Multiple Myeloma - Comparison of Long Term Post Relapse Survival." Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation (October 24, 2017).

PMID
29079457
Full Text

Terebelo, H, Srinivasan, S, Narang, M, Abonour, R, Gasparetto, C, Toomey, K, Hardin, JW, Larkins, G, Kitali, A, Rifkin, RM, and Shah, JJ. "Recognition of early mortality in multiple myeloma by a prediction matrix." American journal of hematology 92, no. 9 (September 2017): 915-923.

PMID
28543165
Full Text

Shah, JJ, Abonour, R, Gasparetto, C, Hardin, JW, Toomey, K, Narang, M, Srinivasan, S, Kitali, A, Zafar, F, Flick, ED, and Rifkin, RM. "Analysis of Common Eligibility Criteria of Randomized Controlled Trials in Newly Diagnosed Multiple Myeloma Patients and Extrapolating Outcomes." Clinical lymphoma, myeloma & leukemia 17, no. 9 (September 2017): 575-583.e2.

PMID
28886839
Full Text

Vogl, DT, Martin, TG, Vij, R, Hari, P, Mikhael, JR, Siegel, D, Wu, KL, Delforge, M, and Gasparetto, C. "Phase I/II study of the novel proteasome inhibitor delanzomib (CEP-18770) for relapsed and refractory multiple myeloma." Leukemia & lymphoma 58, no. 8 (August 2017): 1872-1879.

PMID
28140719
Full Text

Anand, S, Thomas, S, Hyslop, T, Adcock, J, Corbet, K, Gasparetto, C, Lopez, R, Long, GD, Morris, AK, Rizzieri, DA, Sullivan, KM, Sung, AD, Sarantopoulos, S, Chao, NJ, and Horwitz, ME. "Transplantation of Ex Vivo Expanded Umbilical Cord Blood (NiCord) Decreases Early Infection and Hospitalization." Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 23, no. 7 (July 2017): 1151-1157.

PMID
28392378
Full Text

Sivaraj, D, Green, MM, and Gasparetto, C. "Panobinostat for the management of multiple myeloma." Future oncology (London, England) 13, no. 6 (March 2017): 477-488. (Review)

PMID
27776419
Full Text

Kumar, SK, Callander, NS, Alsina, M, Atanackovic, D, Biermann, JS, Chandler, JC, Costello, C, Faiman, M, Fung, HC, Gasparetto, C, Godby, K, Hofmeister, C, Holmberg, L, Holstein, S, Huff, CA, Kassim, A, Liedtke, M, Martin, T, Omel, J, Raje, N, Reu, FJ, Singhal, S, Somlo, G, Stockerl-Goldstein, K, Treon, SP, Weber, D, Yahalom, J, Shead, DA, and Kumar, R. "Clinical practice guidelines in oncology." JNCCN Journal of the National Comprehensive Cancer Network 15, no. 2 (February 1, 2017): 230-269.

Scholars@Duke

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