Cynthia Ann Moylan, MD

Assistant Professor of Medicine
Member of the Duke Cancer Institute
Campus mail 905 S Lasalle St, Gsrb1, DUMC 3256, Durham, NC 27710
Phone (919) 668-0401
Email address cynthia.moylan@duke.edu

My research interests focus on the study of chronic liver disease and primary liver cancer, particularly from nonalcoholic fatty liver disease (NAFLD).  As part of the NAFLD Research Team at Duke, I am investigating the role of epigenetics and genetics on the development of advanced fibrosis from NAFLD.  The long term goal of our research is to develop non-invasive biomarkers to identify those patients at increased risk for cirrhosis and end stage liver disease in order to risk stratify patients as well as to develop better preventative and therapeutic strategies.  

Education and Training

  • Fellow In Gastroenterology, Medicine, Duke University, 2005 - 2009
  • Resident, Medicine, Duke University, 2002 - 2005
  • M.D., University of Miami, 2002

Publications

Patel, YA, Henao, R, Moylan, CA, Guy, CD, Piercy, DL, Diehl, AM, and Abdelmalek, MF. "Reply to Kim et al." The American journal of gastroenterology 112, no. 5 (May 2017): 807-808.

PMID
28469220
Full Text

Moylan, CA, Giraldo, RH, Murphy, SK, Diehl, AM, and Abdelmalek, MF. "DIFFERENTIAL DNA METHYLATION IN WHOLE BLOOD REFLECTS THAT IN LIVER AND DISTINGUISHES PATIENTS WITH ADVANCED NAFLD FIBROSIS FROM THOSE WITH NORMAL HISTOLOGY: A POTENTIAL NON-INVASIVE TOOL." April 2017.

Scholars@Duke

Mwinyi, J, Boström, AE, Pisanu, C, Murphy, SK, Erhart, W, Schafmayer, C, Hampe, J, Moylan, C, and Schiöth, HB. "NAFLD is associated with methylation shifts with relevance for the expression of genes involved in lipoprotein particle composition." Biochimica et biophysica acta 1862, no. 3 (March 2017): 314-323.

PMID
27993651
Full Text

Patel, YA, Henao, R, Moylan, CA, Guy, CD, Piercy, DL, Diehl, AM, and Abdelmalek, MF. "Vitamin D is Not Associated With Severity in NAFLD: Results of a Paired Clinical and Gene Expression Profile Analysis." The American journal of gastroenterology 111, no. 11 (November 2016): 1591-1598.

PMID
27644736
Full Text

Suzuki, A, Spencer, HJ, Moylan, CA, Dranoff, JA, Abdelmalek, MF, Guy, CD, and Diehl, AM. "Hepatic estrogen transcriptional activity and estrogen receptor a gene expression are negatively correlated with fibrosis stage in patients with nonalcoholic fatty liver disease (NAFLD)." October 2016.

Scholars@Duke

Wegermann, K, Henao, R, Pan, Y, Diehl, AM, Abdelmalek, MF, and Moylan, CA. "BCAT1 is Associated with Clinical Decompensation in NAFLD: A Pilot Study." October 2016.

Scholars@Duke

Patel, YA, Henao, R, Moylan, CA, Guy, CD, Piercy, DL, Diehl, AM, and Abdelmalek, MF. "Vitamin D is Not Associated with Histologic Severity in NAFLD: Results of a Paired Clinical and Hepatic Gene Expression Profile Analysis." October 2016.

Scholars@Duke

Moylan, CA, and Murphy, SK. "DNA Methylation: Basic Principles." In Medical Epigenetics, 11-31. July 1, 2016.

Full Text

Wilder, JM, Oloruntoba, OO, Muir, AJ, and Moylan, CA. "Role of patient factors, preferences, and distrust in health care and access to liver transplantation and organ donation." Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 22, no. 7 (July 2016): 895-905.

PMID
27027394
Full Text

"Liver Transplantation for Nonalcoholic Fatty Liver Disease: Role of Bariatric Surgery for Comorbid Obesity." Journal of Advanced Nutrition and Human Metabolism (June 23, 2016).

Full Text

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