Gastroenterology

Cynthia Ann Moylan, MD

Associate Professor of Medicine
Associate Professor in Pathology
Member of the Duke Cancer Institute
Campus mail 905 S Lasalle St, Gsrb1, DUMC 3256, Durham, NC 27710
Phone (919) 668-0401
Email address cynthia.moylan@duke.edu

My research interests focus on the study of chronic liver disease and primary liver cancer, particularly from nonalcoholic fatty liver disease (NAFLD).  As part of the NAFLD Research Team at Duke, I am investigating the role of epigenetics and genetics on the development of advanced fibrosis from NAFLD.  The long term goal of our research is to develop non-invasive biomarkers to identify those patients at increased risk for cirrhosis and end stage liver disease in order to risk stratify patients as well as to develop better preventative and therapeutic strategies.  

Education and Training

  • Fellow in Gastroenterology, Medicine, Duke University, 2005 - 2009
  • Resident, Medicine, Duke University, 2002 - 2005
  • M.D., University of Miami, 2002

Grants

Publications

Wegermann, Kara, Ayako Suzuki, Alisha M. Mavis, Manal F. Abdelmalek, Anna Mae Diehl, and Cynthia A. Moylan. “Tackling Nonalcoholic Fatty Liver Disease: Three Targeted Populations.” Hepatology 73, no. 3 (March 2021): 1199–1206. https://doi.org/10.1002/hep.31533.

PMID
32865242
Full Text

Lee, Tzu-Hao, Austin Chan, William Bryan, Lawrence Park, Mohamed Hashem, Mary Townsend, Cynthia Moylan, Rachel Britt, Steve Choi, and Susanna Naggie. “Proton pump inhibitor usage reduces sustained viral response rates for veterans with HIV/HCV coinfection on ledipasvir/sofosbuvir: a real-world study from a multicentre VA cohort.” J Viral Hepat, December 30, 2020. https://doi.org/10.1111/jvh.13462.

PMID
33378562
Full Text

Naggie, Susanna, Sam Lusk, J Will Thompson, Meredith Mock, Cynthia Moylan, Joseph E. Lucas, Laura Dubois, Lisa St John-Williams, M Arthur Moseley, and Keyur Patel. “Metabolomic Signature as a Predictor of Liver Disease Events in Patients With HIV/HCV Coinfection.” J Infect Dis 222, no. 12 (November 13, 2020): 2012–20. https://doi.org/10.1093/infdis/jiaa316.

PMID
32502252
Full Text

Suzuki, Ayako, Ying Wang, Andrea D. Coviello, Data D. Portenier, Cynthia A. Moylan, Dawn L. Piercy, Cynthia D. Guy, Anna Mae Diehl, and Manal F. Abdelmalek. “HISTORY OF BREASTFEEDING IS ASSOCIATED WITH A DECREASED RISK OF HEPATIC FIBROSIS AMONG YOUNG WOMEN WITH NAFLD.” In Hepatology, 72:65A-65A, 2020.

Scholars@Duke

Moylan, Cynthia A., Dereje Jima, Alisha Mavis, Anna Mae Diehl, Stephanie Buie, Mustafa Bashir, Jeongeun Hyun, et al. “NONALCOHOLIC FATTY LIVER AND ITS RISK FACTORS ASSOCIATE WITH DIFFERENTIAL DNA METHYLATION IN THE PERIPHERAL BLOOD OF PRE-TEENAGE CHILDREN.” In Hepatology, 72:931A-931A, 2020.

Scholars@Duke

Wegermann, Kara, and Cynthia A. Moylan. “Response to: Tackling NAFLD in adolescent PCOS: reducing liver fat to mimick weight loss.” Hepatology, October 11, 2020. https://doi.org/10.1002/hep.31593.

PMID
33040372
Full Text

Benhammou, Jihane N., Andrew M. Moon, Joseph R. Pisegna, Feng Su, Philip Vutien, Cynthia A. Moylan, and George N. Ioannou. “Nonalcoholic Fatty Liver Disease Risk Factors Affect Liver-Related Outcomes After Direct-Acting Antiviral Treatment for Hepatitis C.” Dig Dis Sci, July 11, 2020. https://doi.org/10.1007/s10620-020-06457-2.

PMID
32654086
Full Text

Henson, Jacqueline B., Julius M. Wilder, Matthew R. Kappus, Andrew S. Barbas, Cynthia A. Moylan, Donna Niedzwiecki, Andrew J. Muir, Carl L. Berg, and Yuval A. Patel. “Transplant Outcomes in Older Patients With Nonalcoholic Steatohepatitis Compared to Alcohol-related Liver Disease and Hepatitis C.” Transplantation 104, no. 6 (June 2020): e164–73. https://doi.org/10.1097/TP.0000000000003219.

PMID
32150036
Full Text

Du, Kuo, Satish K. Chitneni, Ayako Suzuki, Ying Wang, Ricardo Henao, Jeongeun Hyun, Richard T. Premont, et al. “Increased Glutaminolysis Marks Active Scarring in Nonalcoholic Steatohepatitis Progression.” Cell Mol Gastroenterol Hepatol 10, no. 1 (2020): 1–21. https://doi.org/10.1016/j.jcmgh.2019.12.006.

PMID
31881361
Full Text

Pages