Medical Oncology

Daphne Ruth Friedman, MD

Associate Professor of Medicine
Member of the Duke Cancer Institute
Campus mail 508 Fulton Street (111g), Durham VA Medical Center, Durham, NC 27705
Phone (919) 286-6944
Email address daphne.friedman@duke.edu

My area of expertise is in leukemias and lymphomas, including Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma. My research interests are focused on improving treatment options for patients with hematologic malignancies, through laboratory and clinical research.  I am also a staff physician at the Durham VA Medical Center, and am deeply committed to expanding treatment options for veterans, including working on clinical trials for multiple myeloma, prostate cancer, and lung cancer at the Durham VA.

Education and Training

  • Fellow in Hematology-Oncology, Medicine, Duke University, 2005 - 2008
  • Medical Resident, Medicine, University of Maryland, College Park, 2002 - 2005
  • M.D., University of Maryland, College Park, 2002

Publications

Weinberg, J Brice, Danielle M. Brander, Dale J. Christensen, and Daphne R. Friedman. “Post-translational regulation could be determine functional differences between SET alpha and beta isoform - Response to Cristóbal et al..” Br J Haematol 186, no. 4 (August 2019). https://doi.org/10.1111/bjh.15934.

PMID
31044417
Full Text

Friedman, Daphne R., Kenneth R. Carson, and J Brice Weinberg. “Reflections on and future of hematologic malignancies research in the Veterans Health Administration..” Semin Oncol 46, no. 4–5 (August 2019): 346–50. https://doi.org/10.1053/j.seminoncol.2019.09.004.

PMID
31699443
Full Text

Friedman, Daphne Ruth, Vikas Patil, Kelli Marie Rasmussen, Brian C. Sauer, Michael J. Kelley, and Ahmad Sami Halwani. “Implementation of the VA Symptom Assessment Scale (VSAS): Five-year experience..” In Journal of Clinical Oncology, 37:e23120–e23120. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.15_suppl.e23120.

Full Text

Brander, Danielle M., Daphne R. Friedman, Alicia D. Volkheimer, Dale J. Christensen, Laura Z. Rassenti, Thomas J. Kipps, Eross Guadalupe, et al. “SET alpha and SET beta mRNA isoforms in chronic lymphocytic leukaemia..” Br J Haematol 184, no. 4 (February 2019): 605–15. https://doi.org/10.1111/bjh.15677.

PMID
30443898
Full Text

Friedman, Daphne R., Eross Guadalupe, Alicia Volkheimer, Joseph O. Moore, and J Brice Weinberg. “Clinical outcomes in chronic lymphocytic leukaemia associated with expression of CD5, a negative regulator of B-cell receptor signalling..” Br J Haematol 183, no. 5 (December 2018): 747–54. https://doi.org/10.1111/bjh.15632.

PMID
30407619
Full Text

Chanfreau, Catherine, Kristine E. Lynch, Ji Won Chang, Daniel J. Becker, Daphne R. Friedman, Donna R. Rivera, Scott L. DuVall, and Julie A. Lynch. “Chronic myeloid leukemia among veterans from 2006 to 2015: Trends in utilization of tyrosine kinase inhibitors.” In Pharmacoepidemiology and Drug Safety, 27:102–3. WILEY, 2018.

Scholars@Duke

Friedman, Daphne R., Alexander B. Sibley, Kouros Owzar, Kari G. Chaffee, Susan Slager, Neil E. Kay, Curtis A. Hanson, et al. “Relationship of blood monocytes with chronic lymphocytic leukemia aggressiveness and outcomes: a multi-institutional study..” Am J Hematol 91, no. 7 (July 2016): 687–91. https://doi.org/10.1002/ajh.24376.

PMID
27037726
Full Text

Holohan, Brody, Moriah M. Hagiopian, Tsung-Po Lai, Ejun Huang, Daphne R. Friedman, Woodring E. Wright, and Jerry W. Shay. “Perifosine as a potential novel anti-telomerase therapy..” Oncotarget 6, no. 26 (September 8, 2015): 21816–26. https://doi.org/10.18632/oncotarget.5200.

PMID
26307677
Full Text

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