Erik Magnus Ohman, MBBS

Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail 7403 Duke North, Durham, NC 27710
Phone (919) 681-2069
Email address ohman001@mc.duke.edu

The main focus of my research is in the management of acute myocardial infarction. My focus has revolved around the use of interventional procedures such as balloon angioplasty, intra-aortic balloon pumping and other support devices for the management of patients with acute myocardial infarction. Through participating and designing a number of randomized trials, we have helped crystallize the management to sustain patency of the infarct-related coronary artery in acute myocardial infarction. Furthermore, I have conducted several large multi-center clinical trials on the use of intra-aortic counterpulsation and angioplasty to better understand the pathophysiology of interventional procedures. Another major focus has been in the area of risk stratification in acute myocardial infarction. Early observations done abroad have led me to use new cardiac markers to identify high and low risk patients. Further research in this area will integrate early and rapid triage along with monitoring of the effect of thrombolysis after reperfusion in patients. A patent in the latter category has already been issued. My continued focus in the performance of multi-center international clinical trials has allowed us to explore different treatment strategies for the management of acute myocardial infarction from an international prospective. We have also collected angioplasty data on nearly 6,000 patients from around North America to further explore international differences in the management of patients using percutaneous interventions.

In Their Words

Education and Training

  • M.B.B.S., Royal College of Surgeons (Ireland), 1981

Publications

Hinohara, TT, Roe, MT, White, HD, Fox, KAA, Bhatt, DL, Hamm, C, Gurbel, PA, Aylward, PE, Wiviott, SD, Huber, K, Neely, ML, and Ohman, EM. "Outcomes of Patients Receiving Downstream Revascularization After Initial Medical Management for Non-ST-Segment Elevation Acute Coronary Syndromes (From the TRILOGY ACS Trial)." The American Journal of Cardiology 122, no. 8 (October 2018): 1322-1329.

PMID
30135019
Full Text

Yan, AT, Roe, MT, Neely, M, Cyr, DD, White, H, Fox, KAA, Prabhakaran, D, Armstrong, PW, Ohman, EM, and Goodman, SG. "Early discontinuation of prasugrel or clopidogrel in acute coronary syndromes: insights from the TRILOGY ACS trial." Coronary Artery Disease 29, no. 6 (September 2018): 469-476.

PMID
29652672
Full Text

O'Neill, WW, Grines, C, Schreiber, T, Moses, J, Maini, B, Dixon, SR, and Ohman, EM. "Analysis of outcomes for 15,259 US patients with acute myocardial infarction cardiogenic shock (AMICS) supported with the Impella device." American Heart Journal 202 (August 2018): 33-38.

PMID
29803984
Full Text

Ohman, EM, and Velazquez, EJ. "Revascularization for Heart Failure: Can We Do Better?." Jacc. Heart Failure 6, no. 6 (June 2018): 527-529.

PMID
29852934
Full Text

Vetrovec, GW, Anderson, M, Schreiber, T, Popma, J, Lombardi, W, Maini, B, Moller, JE, Schäfer, A, Dixon, SR, Hall, S, Ohman, EM, Mindrescu, C, Moses, J, and O'Neill, W. "The cVAD registry for percutaneous temporary hemodynamic support: A prospective registry of Impella mechanical circulatory support use in high-risk PCI, cardiogenic shock, and decompensated heart failure." American Heart Journal 199 (May 2018): 115-121.

PMID
29754648
Full Text

Ohman, EM, and Patel, MR. "Should a Meta-Analysis Guide Our Practice?." Jacc. Cardiovascular Interventions 11, no. 9 (May 2018): 844-846.

PMID
29747914
Full Text

ZuHone, JA, Kowalik, K, Öhman, E, Lau, E, and Nagai, D. "The Galaxy Cluster Merger Catalog: An Online Repository of Mock Observations from Simulated Galaxy Cluster Mergers." The Astrophysical Journal Supplement Series 234, no. 1 (January 1, 2018): 4-4.

Full Text

Ohman, EM. "Secondary prevention shifts into second gear." Lancet (London, England) 391, no. 10117 (January 2018): 181-182.

PMID
29132878
Full Text

de Waha, S, Patel, MR, Granger, CB, Ohman, EM, Maehara, A, Eitel, I, Ben-Yehuda, O, Jenkins, P, Thiele, H, and Stone, GW. "Relationship between microvascular obstruction and adverse events following primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: an individual patient data pooled analysis from seven randomized trials." European Heart Journal 38, no. 47 (December 2017): 3502-3510.

PMID
29020248
Full Text

Alfredsson, J, Neely, B, Neely, ML, Bhatt, DL, Goodman, SG, Tricoci, P, Mahaffey, KW, Cornel, JH, White, HD, Fox, KA, Prabhakaran, D, Winters, KJ, Armstrong, PW, Ohman, EM, Roe, MT, and TRILOGY ACS Investigators, . "Predicting the risk of bleeding during dual antiplatelet therapy after acute coronary syndromes." Heart (British Cardiac Society) 103, no. 15 (August 2017): 1168-1176.

PMID
28381584
Full Text

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