Feng Gao, MD

Professor of Medicine
Member of the Duke Human Vaccine Institute
Campus mail 244 Sands Bldg, Box 102359, Durham, NC 27710
Phone (919) 668-6433
Email address feng.gao@duke.edu

Dr. Feng Gao is Professor of Medicine at Duke University. The Gao laboratory has a long-standing interest in elucidating the origins and evolution of human and simian inmmunodeficiency viruses (HIV and SIV), and in studying HIV/SIV gene function and pathogenic mechanisms from the evolutionary perspective. These studies have led to new strategies to better understand HIV origins,  biology, pathogenesis and drug resistance, and to design new AIDS vaccines.

Education and Training

  • M.D., Harbin Medical University (China), 1984

Publications

Martinez, David R., Amit Kumar, Joshua J. Tu, Jesse F. Mangold, Riley J. Mangan, Ria Goswami, Elena E. Giorgi, et al. “Maternal Broadly Neutralizing Antibodies Select for Neutralization-Resistant Infant Transmitted/Founder HIV Variants,” May 3, 2019.

Scholars@Duke

Zhang, Yuepeng, Chu Wang, Nan Gao, Xiaoyan Zhang, Xianghui Yu, Jianqing Xu, and Feng Gao. “Determination of neutralization activities by a new versatile assay using an HIV-1 genome carrying the Gaussia luciferase gene..” J Virol Methods 267 (May 2019): 22–28. https://doi.org/10.1016/j.jviromet.2019.02.009.

PMID
30817948
Full Text

Chen, Yue, Bhavna Hora, Todd DeMarco, Regina Berba, Heidi Register, Sylvia Hood, Meredith Carter, et al. “Increased predominance of HIV-1 CRF01_AE and its recombinants in the Philippines..” J Gen Virol 100, no. 3 (March 2019): 511–22. https://doi.org/10.1099/jgv.0.001198.

PMID
30676308
Full Text

Hemelaar, Joris, Ramyiadarsini Elangovan, Jason Yun, Leslie Dickson-Tetteh, Isabella Fleminger, Shona Kirtley, Brian Williams, Eleanor Gouws-Williams, Peter D. Ghys, and Peter D. WHO–UNAIDS Network for HIV Isolation Characterisation. “Global and regional molecular epidemiology of HIV-1, 1990-2015: a systematic review, global survey, and trend analysis..” Lancet Infect Dis 19, no. 2 (February 2019): 143–55. https://doi.org/10.1016/S1473-3099(18)30647-9.

PMID
30509777
Full Text

Wang, Chu, Donglai Liu, Tao Zuo, Bhavna Hora, Fangping Cai, Haitao Ding, John Kappes, et al. “Accumulated Mutations Cause Significant Fitness Losses and are Associated with Decreased Viral Loads During Early HIV-1 Infection,” January 19, 2019.

Scholars@Duke

Wagh, Kshitij, Edward F. Kreider, Yingying Li, Hannah J. Barbian, Gerald H. Learn, Elena Giorgi, Peter T. Hraber, et al. “Completeness of HIV-1 Envelope Glycan Shield at Transmission Determines Neutralization Breadth..” Cell Rep 25, no. 4 (October 23, 2018): 893-908.e7. https://doi.org/10.1016/j.celrep.2018.09.087.

PMID
30355496
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Peng, Binghao J., Jonathan M. Carlson, Michael K. P. Liu, Feng Gao, Nilu Goonetilleke, Andrew J. McMichael, Persephone Borrow, et al. “Antisense-Derived HIV-1 Cryptic Epitopes Are Not Major Drivers of Viral Evolution during the Acute Phase of Infection..” J Virol 92, no. 19 (October 1, 2018). https://doi.org/10.1128/JVI.00711-18.

PMID
30021907
Full Text

Martinez, David R., David Martinez, Riley J. Mangan, Elena Georgi, Juilin Chen, Michael Mengual, Jesse Mangold, et al. “Characterizing Env-specific Monoclonal Antibodies Isolated From US and Malawian HIV-infected Non-transmitting and Transmitting Women.” In Aids Research and Human Retroviruses, 34:390–390. MARY ANN LIEBERT, INC, 2018.

Scholars@Duke

Hompe, Eliza D., Amit Kumar, Elena E. Giorgi, Erin McGuire, Genevieve G. Fouda, Feng Gao, and Sallie R. Permar. “Induction of Neutralizing Antibodies Against Autologous Viruses in HIV-1 Infected Pregnant Women Immunized With a gp120/160 Vaccine.” In Aids Research and Human Retroviruses, 34:393–393. MARY ANN LIEBERT, INC, 2018.

Scholars@Duke

Shi, Wei, Yiming Kou, Jinghui Xiao, Lijuan Zhang, Feng Gao, Wei Kong, Weiheng Su, Chunlai Jiang, and Yong Zhang. “Comparison of immunogenicity, efficacy and transcriptome changes of inactivated rabies virus vaccine with different adjuvants..” Vaccine 36, no. 33 (August 9, 2018): 5020–29. https://doi.org/10.1016/j.vaccine.2018.07.006.

PMID
30037417
Full Text

Pages