Feng Gao, MD

Professor of Medicine
Member of the Duke Human Vaccine Institute
Campus mail 244 Sands Bldg, Box 102359, Durham, NC 27710
Phone (919) 668-6433
Email address feng.gao@duke.edu

Dr. Feng Gao is Professor of Medicine at Duke University. The Gao laboratory has a long-standing interest in elucidating the origins and evolution of human and simian inmmunodeficiency viruses (HIV and SIV), and in studying HIV/SIV gene function and pathogenic mechanisms from the evolutionary perspective. These studies have led to new strategies to better understand HIV origins,  biology, pathogenesis and drug resistance, and to design new AIDS vaccines.

Education and Training

  • M.D., Harbin Medical University (China), 1984

Publications

Bi, Jinpeng, Fangshen Li, Mo Zhang, Huaiyu Wang, Jingcai Lu, Yong Zhang, Hong Ling, et al. “An HIV-1 vaccine based on bacterium-like particles elicits Env-specific mucosal immune responses.” Immunol Lett 222 (June 2020): 29–39. https://doi.org/10.1016/j.imlet.2020.03.002.

PMID
32173375
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Ji, Hezhao, Neil Parkin, Feng Gao, Thomas Denny, Cheryl Jennings, Paul Sandstrom, and Rami Kantor. “External Quality Assessment Program for Next-Generation Sequencing-Based HIV Drug Resistance Testing: Logistical Considerations.” Viruses 12, no. 5 (May 18, 2020). https://doi.org/10.3390/v12050556.

PMID
32443529
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Lee, Emma R., Feng Gao, Paul Sandstrom, and Hezhao Ji. “External Quality Assessment for Next-Generation Sequencing-Based HIV Drug Resistance Testing: Unique Requirements and Challenges.” Viruses 12, no. 5 (May 16, 2020). https://doi.org/10.3390/v12050550.

PMID
32429382
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Martinez, David R., Joshua J. Tu, Amit Kumar, Jesse F. Mangold, Riley J. Mangan, Ria Goswami, Elena E. Giorgi, et al. “Maternal Broadly Neutralizing Antibodies Can Select for Neutralization-Resistant, Infant-Transmitted/Founder HIV Variants.” Mbio 11, no. 2 (March 10, 2020). https://doi.org/10.1128/mBio.00176-20.

PMID
32156815
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Martinez, David R., Joshua J. Tu, Amit Kumar, Jesse F. Mangold, Riley J. Mangan, Ria Goswami, Elena E. Giorgi, et al. “Maternal Broadly Neutralizing Antibodies Can Select for Neutralization-Resistant, Infant-Transmitted/Founder HIV Variants.” Mbio 11, no. 2 (March 1, 2020). https://doi.org/10.1128/mBio.00176.20.

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Wang, Chu, Donglai Liu, Tao Zuo, Bhavna Hora, Fangping Cai, Haitao Ding, John Kappes, et al. “Accumulated mutations by 6 months of infection collectively render transmitted/founder HIV-1 significantly less fit.” J Infect 80, no. 2 (February 2020): 210–18. https://doi.org/10.1016/j.jinf.2019.12.001.

PMID
31812703
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Wang, Chu, Nan Gao, Yanan Song, Sizhu Duan, Wei Wang, Zhe Cong, Chuan Qin, Chunlai Jiang, Xianghui Yu, and Feng Gao. “Reduction of peak viremia by an integration-defective SIV proviral DNA vaccine in rhesus macaques.” Microbiol Immunol 64, no. 1 (January 2020): 52–62. https://doi.org/10.1111/1348-0421.12744.

PMID
31544982
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Zhang, Yuepeng, Chu Wang, Nan Gao, Xiaoyan Zhang, Xianghui Yu, Jianqing Xu, and Feng Gao. “Determination of neutralization activities by a new versatile assay using an HIV-1 genome carrying the Gaussia luciferase gene.” J Virol Methods 267 (May 2019): 22–28. https://doi.org/10.1016/j.jviromet.2019.02.009.

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30817948
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Chen, Yue, Bhavna Hora, Todd DeMarco, Regina Berba, Heidi Register, Sylvia Hood, Meredith Carter, et al. “Increased predominance of HIV-1 CRF01_AE and its recombinants in the Philippines.” J Gen Virol 100, no. 3 (March 2019): 511–22. https://doi.org/10.1099/jgv.0.001198.

PMID
30676308
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Hemelaar, Joris, Ramyiadarsini Elangovan, Jason Yun, Leslie Dickson-Tetteh, Isabella Fleminger, Shona Kirtley, Brian Williams, Eleanor Gouws-Williams, Peter D. Ghys, and Peter D. WHO–UNAIDS Network for HIV Isolation Characterisation. “Global and regional molecular epidemiology of HIV-1, 1990-2015: a systematic review, global survey, and trend analysis.” Lancet Infect Dis 19, no. 2 (February 2019): 143–55. https://doi.org/10.1016/S1473-3099(18)30647-9.

PMID
30509777
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