Feng Gao, MD

Professor of Medicine
Member of the Duke Human Vaccine Institute
Campus mail 244 Sands Bldg, Box 102359, Durham, NC 27710
Phone (919) 668-6433
Email address feng.gao@duke.edu

Dr. Feng Gao is Professor of Medicine at Duke University. The Gao laboratory has a long-standing interest in elucidating the origins and evolution of human and simian inmmunodeficiency viruses (HIV and SIV), and in studying HIV/SIV gene function and pathogenic mechanisms from the evolutionary perspective. These studies have led to new strategies to better understand HIV origins,  biology, pathogenesis and drug resistance, and to design new AIDS vaccines.

Education and Training

  • M.D., Harbin Medical University (China), 1984

Publications

Gao, N, Wang, W, Wang, C, Gu, T, Guo, R, Yu, B, Kong, W, Qin, C, Giorgi, EE, Chen, Z, Townsley, S, Hu, S-L, Yu, X, and Gao, F. "Development of broad neutralization activity in simian/human immunodeficiency virus-infected rhesus macaques after long-term infection." AIDS (London, England) 32, no. 5 (March 2018): 555-563.

PMID
29239895
Full Text

Gao, Y, Tian, W, Han, X, and Gao, F. "Immunological and virological characteristics of human immunodeficiency virus type 1 superinfection: implications in vaccine design." Frontiers of medicine 11, no. 4 (December 2017): 480-489. (Review)

PMID
29170914
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Williams, WB, Zhang, J, Jiang, C, Nicely, NI, Fera, D, Luo, K, Moody, MA, Liao, H-X, Alam, SM, Kepler, TB, Ramesh, A, Wiehe, K, Holland, JA, Bradley, T, Vandergrift, N, Saunders, KO, Parks, R, Foulger, A, Xia, S-M, Bonsignori, M, Montefiori, DC, Louder, M, Eaton, A, Santra, S, Scearce, R, Sutherland, L, Newman, A, Bouton-Verville, H, Bowman, C, Bomze, H, Gao, F, Marshall, DJ, Whitesides, JF, Nie, X, Kelsoe, G, Reed, SG, Fox, CB, Clary, K, Koutsoukos, M, Franco, D, Mascola, JR, and Harrison, SC et al. "Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations." Nature communications 8, no. 1 (November 23, 2017): 1732-.

PMID
29170366
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Liu, D, Wang, C, Hora, B, Zuo, T, Goonetilleke, N, Liu, MKP, Berrong, M, Ferrari, G, McMichael, AJ, Bhattacharya, T, Perelson, AS, and Gao, F. "A strongly selected mutation in the HIV-1 genome is independent of T cell responses and neutralizing antibodies." Retrovirology 14, no. 1 (October 10, 2017): 46-.

PMID
29017536
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Rademeyer, C, Korber, B, Seaman, MS, Giorgi, EE, Thebus, R, Robles, A, Sheward, DJ, Wagh, K, Garrity, J, Carey, BR, Gao, H, Greene, KM, Tang, H, Bandawe, GP, Marais, JC, Diphoko, TE, Hraber, P, Tumba, N, Moore, PL, Gray, GE, Kublin, J, McElrath, MJ, Vermeulen, M, Middelkoop, K, Bekker, L-G, Hoelscher, M, Maboko, L, Makhema, J, Robb, ML, Karim, SA, Karim, QA, Kim, JH, Hahn, BH, Gao, F, Swanstrom, R, Morris, L, Montefiori, DC, and Williamson, C. "Correction: Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization." PLoS pathogens 13, no. 9 (September 25, 2017): e1006641-.

PMID
28945784
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Meyerhoff, RR, Scearce, RM, Ogburn, DF, Lockwood, B, Pickeral, J, Kuraoka, M, Anasti, K, Eudailey, J, Eaton, A, Cooper, M, Wiehe, K, Montefiori, DC, Tomaras, G, Ferrari, G, Alam, SM, Liao, H-X, Korber, B, Gao, F, and Haynes, BF. "HIV-1 Consensus Envelope-Induced Broadly Binding Antibodies." AIDS research and human retroviruses 33, no. 8 (August 2017): 859-868.

PMID
28314374
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Kijak, GH, Sanders-Buell, E, Chenine, A-L, Eller, MA, Goonetilleke, N, Thomas, R, Leviyang, S, Harbolick, EA, Bose, M, Pham, P, Oropeza, C, Poltavee, K, O'Sullivan, AM, Billings, E, Merbah, M, Costanzo, MC, Warren, JA, Slike, B, Li, H, Peachman, KK, Fischer, W, Gao, F, Cicala, C, Arthos, J, Eller, LA, O'Connell, RJ, Sinei, S, Maganga, L, Kibuuka, H, Nitayaphan, S, Rao, M, Marovich, MA, Krebs, SJ, Rolland, M, Korber, BT, Shaw, GM, Michael, NL, Robb, ML, Tovanabutra, S, and Kim, JH. "Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection." PLoS pathogens 13, no. 7 (July 31, 2017): e1006510-.

PMID
28759651
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Wang, C, Jiang, C, Gao, N, Zhang, K, Liu, D, Wang, W, Cong, Z, Qin, C, Ganusov, VV, Ferrari, G, LaBranche, C, Montefiori, DC, Kong, W, Yu, X, and Gao, F. "Immunologic and Virologic Mechanisms for Partial Protection from Intravenous Challenge by an Integration-Defective SIV Vaccine." Viruses 9, no. 6 (June 2, 2017).

PMID
28574482
Full Text

Bonsignori, M, Kreider, EF, Fera, D, Meyerhoff, RR, Bradley, T, Wiehe, K, Alam, SM, Aussedat, B, Walkowicz, WE, Hwang, K-K, Saunders, KO, Zhang, R, Gladden, MA, Monroe, A, Kumar, A, Xia, S-M, Cooper, M, Louder, MK, McKee, K, Bailer, RT, Pier, BW, Jette, CA, Kelsoe, G, Williams, WB, Morris, L, Kappes, J, Wagh, K, Kamanga, G, Cohen, MS, Hraber, PT, Montefiori, DC, Trama, A, Liao, H-X, Kepler, TB, Moody, MA, Gao, F, Danishefsky, SJ, Mascola, JR, Shaw, GM, Hahn, BH, Harrison, SC, and Korber, BT et al. "Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies." Science translational medicine 9, no. 381 (March 2017).

PMID
28298420
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Bonsignori, M, Liao, H-X, Gao, F, Williams, WB, Alam, SM, Montefiori, DC, and Haynes, BF. "Antibody-virus co-evolution in HIV infection: paths for HIV vaccine development." Immunological reviews 275, no. 1 (January 2017): 145-160. (Review)

PMID
28133802
Full Text

Pages