Feng Gao, MD

Professor of Medicine
Member of the Duke Human Vaccine Institute
Campus mail 244 Sands Bldg, Box 102359, Durham, NC 27710
Phone (919) 668-6433
Email address feng.gao@duke.edu

Dr. Feng Gao is Professor of Medicine at Duke University. The Gao laboratory has a long-standing interest in elucidating the origins and evolution of human and simian inmmunodeficiency viruses (HIV and SIV), and in studying HIV/SIV gene function and pathogenic mechanisms from the evolutionary perspective. These studies have led to new strategies to better understand HIV origins,  biology, pathogenesis and drug resistance, and to design new AIDS vaccines.

Education and Training

  • M.D., Harbin Medical University (China), 1984

Publications

Kou, Yiming, Mingming Wan, Wei Shi, Jie Liu, Zhilei Zhao, Yongqing Xu, Wei Wei, et al. “Performance of Homologous and Heterologous Prime-Boost Immunization Regimens of Recombinant Adenovirus and Modified Vaccinia Virus Ankara Expressing an Ag85B-TB10.4 Fusion Protein against Mycobacterium tuberculosis..” J Microbiol Biotechnol 28, no. 6 (June 28, 2018): 1022–29. https://doi.org/10.4014/jmb.1712.12064.

PMID
29847865
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Shi, Wei, Yiming Kou, Hao Jiang, Feng Gao, Wei Kong, Weiheng Su, Fei Xu, and Chunlai Jiang. “Novel intranasal pertussis vaccine based on bacterium-like particles as a mucosal adjuvant..” Immunol Lett 198 (June 2018): 26–32. https://doi.org/10.1016/j.imlet.2018.03.012.

PMID
29601940
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Song, Hongshuo, Elena E. Giorgi, Vitaly V. Ganusov, Fangping Cai, Gayathri Athreya, Hyejin Yoon, Oana Carja, et al. “Tracking HIV-1 recombination to resolve its contribution to HIV-1 evolution in natural infection..” Nat Commun 9, no. 1 (May 15, 2018). https://doi.org/10.1038/s41467-018-04217-5.

PMID
29765018
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Kumar, Amit, Claire E. P. Smith, Elena E. Giorgi, Joshua Eudailey, David R. Martinez, Karina Yusim, Ayooluwa O. Douglas, et al. “Infant transmitted/founder HIV-1 viruses from peripartum transmission are neutralization resistant to paired maternal plasma..” Plos Pathog 14, no. 4 (April 2018). https://doi.org/10.1371/journal.ppat.1006944.

PMID
29672607
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Gao, Nan, Wei Wang, Chu Wang, Tiejun Gu, Rui Guo, Bin Yu, Wei Kong, et al. “Development of broad neutralization activity in simian/human immunodeficiency virus-infected rhesus macaques after long-term infection..” Aids 32, no. 5 (March 13, 2018): 555–63. https://doi.org/10.1097/QAD.0000000000001724.

PMID
29239895
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Dai, Wenwen, Yu Wu, Jinpeng Bi, Shuai Wang, Fang Li, Wei Kong, Julien Barbier, et al. “Antiviral Effects of ABMA against Herpes Simplex Virus Type 2 In Vitro and In Vivo..” Viruses 10, no. 3 (March 9, 2018). https://doi.org/10.3390/v10030119.

PMID
29522484
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Gao, Yang, Wen Tian, Xiaoxu Han, and Feng Gao. “Immunological and virological characteristics of human immunodeficiency virus type 1 superinfection: implications in vaccine design..” Front Med 11, no. 4 (December 2017): 480–89. https://doi.org/10.1007/s11684-017-0594-8.

PMID
29170914
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Williams, Wilton B., Jinsong Zhang, Chuancang Jiang, Nathan I. Nicely, Daniela Fera, Kan Luo, M Anthony Moody, et al. “Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations..” Nat Commun 8, no. 1 (November 23, 2017). https://doi.org/10.1038/s41467-017-01336-3.

PMID
29170366
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Liu, Donglai, Chu Wang, Bhavna Hora, Tao Zuo, Nilu Goonetilleke, Michael K. P. Liu, Mark Berrong, et al. “A strongly selected mutation in the HIV-1 genome is independent of T cell responses and neutralizing antibodies..” Retrovirology 14, no. 1 (October 10, 2017). https://doi.org/10.1186/s12977-017-0371-4.

PMID
29017536
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Kou, Yiming, Yongqing Xu, Zhilei Zhao, Jie Liu, Yang Wu, Qingrui You, Linli Wang, Feng Gao, Linjun Cai, and Chunlai Jiang. “Tissue plasminogen activator (tPA) signal sequence enhances immunogenicity of MVA-based vaccine against tuberculosis..” Immunol Lett 190 (October 2017): 51–57. https://doi.org/10.1016/j.imlet.2017.07.007.

PMID
28728855
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