Feng Gao, MD

Professor of Medicine
Member of the Duke Human Vaccine Institute
Campus mail 244 Sands Bldg, Box 102359, Durham, NC 27710
Phone (919) 668-6433
Email address feng.gao@duke.edu

Dr. Feng Gao is Professor of Medicine at Duke University. The Gao laboratory has a long-standing interest in elucidating the origins and evolution of human and simian inmmunodeficiency viruses (HIV and SIV), and in studying HIV/SIV gene function and pathogenic mechanisms from the evolutionary perspective. These studies have led to new strategies to better understand HIV origins,  biology, pathogenesis and drug resistance, and to design new AIDS vaccines.

Education and Training

  • M.D., Harbin Medical University (China), 1984

Publications

Williams, Wilton B., Jinsong Zhang, Chuancang Jiang, Nathan I. Nicely, Daniela Fera, Kan Luo, M Anthony Moody, et al. “Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations..” Nat Commun 8, no. 1 (November 23, 2017). https://doi.org/10.1038/s41467-017-01336-3.

PMID
29170366
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Liu, Donglai, Chu Wang, Bhavna Hora, Tao Zuo, Nilu Goonetilleke, Michael K. P. Liu, Mark Berrong, et al. “A strongly selected mutation in the HIV-1 genome is independent of T cell responses and neutralizing antibodies..” Retrovirology 14, no. 1 (October 10, 2017). https://doi.org/10.1186/s12977-017-0371-4.

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29017536
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Kou, Yiming, Yongqing Xu, Zhilei Zhao, Jie Liu, Yang Wu, Qingrui You, Linli Wang, Feng Gao, Linjun Cai, and Chunlai Jiang. “Tissue plasminogen activator (tPA) signal sequence enhances immunogenicity of MVA-based vaccine against tuberculosis..” Immunol Lett 190 (October 2017): 51–57. https://doi.org/10.1016/j.imlet.2017.07.007.

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28728855
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Rademeyer, Cecilia, Bette Korber, Michael S. Seaman, Elena E. Giorgi, Ruwayhida Thebus, Alexander Robles, Daniel J. Sheward, et al. “Correction: Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization..” Plos Pathog 13, no. 9 (September 2017). https://doi.org/10.1371/journal.ppat.1006641.

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28945784
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Su, Weiheng, Xue Li, Meili Chen, Wenwen Dai, Shiyang Sun, Shuai Wang, Xin Sheng, et al. “Synonymous codon usage analysis of hand, foot and mouth disease viruses: A comparative study on coxsackievirus A6, A10, A16, and enterovirus 71 from 2008 to 2015..” Infect Genet Evol 53 (September 2017): 212–17. https://doi.org/10.1016/j.meegid.2017.06.004.

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28602802
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Meyerhoff, R Ryan, Richard M. Scearce, Damon F. Ogburn, Brad Lockwood, Joy Pickeral, Masa Kuraoka, Kara Anasti, et al. “HIV-1 Consensus Envelope-Induced Broadly Binding Antibodies..” Aids Res Hum Retroviruses 33, no. 8 (August 2017): 859–68. https://doi.org/10.1089/AID.2016.0294.

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28314374
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Dai, Wenwen, Yu Wu, Jinpeng Bi, Xiaotong Lu, Ali Hou, Yan Zhou, Bo Sun, et al. “Antiviral effects of Retro-2cycl and Retro-2.1 against Enterovirus 71 in vitro and in vivo..” Antiviral Res 144 (August 2017): 311–21. https://doi.org/10.1016/j.antiviral.2017.07.001.

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28688753
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Kijak, Gustavo H., Eric Sanders-Buell, Agnes-Laurence Chenine, Michael A. Eller, Nilu Goonetilleke, Rasmi Thomas, Sivan Leviyang, et al. “Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection..” Plos Pathog 13, no. 7 (July 2017). https://doi.org/10.1371/journal.ppat.1006510.

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28759651
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Wang, Chu, Chunlai Jiang, Nan Gao, Kaikai Zhang, Donglai Liu, Wei Wang, Zhe Cong, et al. “Immunologic and Virologic Mechanisms for Partial Protection from Intravenous Challenge by an Integration-Defective SIV Vaccine..” Viruses 9, no. 6 (June 2, 2017). https://doi.org/10.3390/v9060135.

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28574482
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Liu, Wei, Yan Zhou, Ziyan Wang, Zeqiang Zhang, Qizhi Wang, Weiheng Su, Yan Chen, et al. “Evaluation of recombinant adenovirus vaccines based on glycoprotein D and truncated UL25 against herpes simplex virus type 2 in mice..” Microbiol Immunol 61, no. 5 (May 2017): 176–84. https://doi.org/10.1111/1348-0421.12482.

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28378925
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Pages