Francis Joseph Keefe, PhD

Professor in Psychiatry and Behavioral Sciences
Professor in Psychology andNeuroscience
Professor in Anesthesiology
Professor in Medicine
Member of the Duke Cancer Institute
Campus mail 2200 W Main St, Suite 340, Durham, NC 27705
Phone (919) 416-3400
Email address keefe003@mc.duke.edu

The primary aim of our research over the past year has been to evaluate the efficacy of cognitive-behavioral treatments for arthritis pain. We are conducting two treatment outcome studies supported by grants from the National Institute of Arthritis, Musculoskeletal, and Skin Diseases. The first project, conducted with osteoarthritis patients, seeks to determine whether aerobic exercise training can enhance the effects of a cognitive behavior therapy (CBT) intervention for managing pain and disability. The CBT intervention is innovative in that it systematically involves spouses in training in pain coping skills. The second project, tests the long-term effectiveness of a relapse prevention training intervention. This study will feature the use of newly developed daily study methods to analyze the long-term effects of pain coping skills training on daily pain.

In addition, in conjunction with Lara Schanberg of the Department of Medicine we are carrying out a study funded by the Arthritis Foundation that examines the effects of a pain coping skills training regimen for pediatric fibromyalgia patients.

Finally, we are currently gathering pilot data for two new research projects. One project seeks to evaluate the efficacy of a cognitive behavior theapy and education intervention for managing pain in patients having breast cancer and prostate cancer. The second project examines the efficacy of patient controlled compression protocol in the management of pain during mammography.

Education and Training

  • Ph.D., Ohio University, 1975
  • M.S., Ohio State University, 1973
  • B.A., Bowdoin College, 1971

Grants

Publications

Somers, Tamara J., James A. Blumenthal, Caroline S. Dorfman, Kim M. Huffman, Sara N. Edmond, Shannon N. Miller, Anava A. Wren, David Caldwell, and Francis J. Keefe. “Effects of a Weight and Pain Management Program in Patients With Rheumatoid Arthritis With Obesity: A Randomized Controlled Pilot Investigation.” J Clin Rheumatol 28, no. 1 (January 1, 2022): 7–13. https://doi.org/10.1097/RHU.0000000000001793.

PMID
34670994
Full Text

Eccleston, Christopher, Francis J. Keefe, and Amanda C. de C Williams. “Basic and applied psychology in PAIN: where we have been and where we are headed.” Pain 162, no. 12 (December 1, 2021): 2785–88. https://doi.org/10.1097/j.pain.0000000000002414.

PMID
34294664
Full Text

Scullin, Michael K., Winston E. Jones, Richard Phenis, Samantha Beevers, Sabra Rosen, Kara Dinh, Andrew Kiselica, Francis J. Keefe, and Jared F. Benge. “Using smartphone technology to improve prospective memory functioning: A randomized controlled trial.” J Am Geriatr Soc, November 17, 2021. https://doi.org/10.1111/jgs.17551.

PMID
34786698
Full Text

Kelleher, Sarah A., Hannah M. Fisher, Joseph G. Winger, Tamara J. Somers, Hope E. Uronis, Arianna N. Wright, and Francis J. Keefe. “Feasibility, engagement, and acceptability of a behavioral pain management intervention for colorectal cancer survivors with pain and psychological distress: data from a pilot randomized controlled trial.” Support Care Cancer 29, no. 9 (September 2021): 5361–69. https://doi.org/10.1007/s00520-021-06126-8.

PMID
33686520
Full Text

Myers, Heather, Francis Keefe, Steven Z. George, June Kennedy, Ashley Davis Lake, Corina Martinez, and Chad Cook. “The influence of a cognitive behavioural approach on changing patient expectations for conservative care in shoulder pain treatment: a protocol for a pragmatic randomized controlled trial.” Bmc Musculoskelet Disord 22, no. 1 (August 24, 2021): 727. https://doi.org/10.1186/s12891-021-04588-9.

PMID
34429074
Full Text

Rini, Christine, Ariana W. K. Katz, Ada Nwadugbo, Laura S. Porter, Tamara J. Somers, and Francis J. Keefe. “Changes in Identification of Possible Pain Coping Strategies by People with Osteoarthritis who Complete Web-based Pain Coping Skills Training.” International Journal of Behavioral Medicine 28, no. 4 (August 2021): 488–98. https://doi.org/10.1007/s12529-020-09938-w.

PMID
33174614
Full Text

Allen, Kelli D., Tyler Beauchamp, Christine Rini, Francis J. Keefe, Kim L. Bennell, Rebecca J. Cleveland, Kimberlea Grimm, et al. “Pilot study of an internet-based pain coping skills training program for patients with systemic Lupus Erythematosus.” Bmc Rheumatol 5, no. 1 (June 17, 2021): 20. https://doi.org/10.1186/s41927-021-00191-6.

PMID
34134788
Full Text

Riddle, Daniel L., James Slover, Francis J. Keefe, Dennis C. Ang, Levent Dumenci, and Robert A. Perera. “Racial Differences in Pain and Function Following Knee Arthroplasty: A Secondary Analysis From a Multicenter Randomized Clinical Trial.” Arthritis Care Res (Hoboken) 73, no. 6 (June 2021): 810–17. https://doi.org/10.1002/acr.24177.

PMID
32144884
Full Text

Carson, James W., Kimberly M. Carson, Maren Olsen, Linda Sanders, Kelly Westbrook, Francis J. Keefe, and Laura S. Porter. “Yoga Practice Predicts Improvements in Day-to-Day Pain in Women With Metastatic Breast Cancer.” J Pain Symptom Manage 61, no. 6 (June 2021): 1227–33. https://doi.org/10.1016/j.jpainsymman.2020.10.009.

PMID
33065208
Full Text

Pages