Francis Joseph Keefe, PhD

Professor in Psychiatry and Behavioral Sciences
Professor in Psychology andNeuroscience
Professor in Anesthesiology
Professor in Medicine
Member of the Duke Cancer Institute
Campus mail 2200 W Main St, Suite 340, Durham, NC 27705
Phone (919) 416-3400
Email address keefe003@mc.duke.edu

The primary aim of our research over the past year has been to evaluate the efficacy of cognitive-behavioral treatments for arthritis pain. We are conducting two treatment outcome studies supported by grants from the National Institute of Arthritis, Musculoskeletal, and Skin Diseases. The first project, conducted with osteoarthritis patients, seeks to determine whether aerobic exercise training can enhance the effects of a cognitive behavior therapy (CBT) intervention for managing pain and disability. The CBT intervention is innovative in that it systematically involves spouses in training in pain coping skills. The second project, tests the long-term effectiveness of a relapse prevention training intervention. This study will feature the use of newly developed daily study methods to analyze the long-term effects of pain coping skills training on daily pain.

In addition, in conjunction with Lara Schanberg of the Department of Medicine we are carrying out a study funded by the Arthritis Foundation that examines the effects of a pain coping skills training regimen for pediatric fibromyalgia patients.

Finally, we are currently gathering pilot data for two new research projects. One project seeks to evaluate the efficacy of a cognitive behavior theapy and education intervention for managing pain in patients having breast cancer and prostate cancer. The second project examines the efficacy of patient controlled compression protocol in the management of pain during mammography.

Education and Training

  • Ph.D., Ohio State University, 1975
  • M.S., Ohio State University, 1973
  • B.A., Bowdoin College, 1971

Publications

Rini, C, Vu, MB, Lerner, H, Bloom, C, Carda-Auten, J, Wood, WA, Basch, EM, Voorhees, PM, Reeder-Hayes, KE, and Keefe, FJ. "A qualitative study of patient and provider perspectives on using web-based pain coping skills training to treat persistent cancer pain." Palliative & supportive care 16, no. 2 (April 2018): 155-169.

PMID
28264744
Full Text

O'Sullivan, ML, Shelby, RA, Dorfman, CS, Kelleher, SA, Fisher, HM, Rowe Nichols, KA, Keefe, FJ, Sung, AD, and Somers, TJ. "The effect of pre-transplant pain and chronic disease self-efficacy on quality of life domains in the year following hematopoietic stem cell transplantation." Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 26, no. 4 (April 2018): 1243-1252.

PMID
29124418
Full Text

DeBar, L, Benes, L, Bonifay, A, Deyo, RA, Elder, CR, Keefe, FJ, Leo, MC, McMullen, C, Mayhew, M, Owen-Smith, A, Smith, DH, Trinacty, CM, and Vollmer, WM. "Interdisciplinary team-based care for patients with chronic pain on long-term opioid treatment in primary care (PPACT) - Protocol for a pragmatic cluster randomized trial." Contemporary clinical trials 67 (April 2018): 91-99.

PMID
29522897
Full Text

Lumley, MA, Anderson, T, Ankawi, B, Goldman, G, Perri, LM, Bianco, JA, and Keefe, FJ. "The working alliance and Clinician-assisted Emotional Disclosure for rheumatoid arthritis." Journal of psychosomatic research 104 (January 2018): 9-15.

PMID
29275791
Full Text

Porter, LS, and Keefe, FJ. "Couple-based communication interventions for cancer: moving beyond a 'one size fits all' approach." Acta oncologica (Stockholm, Sweden) (December 8, 2017): 1-2.

PMID
29219014
Full Text

Gerhart, JI, Burns, JW, Bruehl, S, Smith, DA, Post, KM, Porter, LS, Schuster, E, Buvanendran, A, Fras, AM, and Keefe, FJ. "Variability in negative emotions among individuals with chronic low back pain: relationships with pain and function." Pain (November 13, 2017).

PMID
29140926
Full Text

Burns, JW, Post, KM, Smith, DA, Porter, LS, Buvanendran, A, Fras, AM, and Keefe, FJ. "Spouse criticism and hostility during marital interaction: effects on pain intensity and behaviors among individuals with chronic low back pain." Pain (October 2017).

PMID
28796117
Full Text

Lefebvre, JC, Jensen, MP, Waters, SJ, Molton, IR, Keefe, FJ, and Caldwell, DS. "The development and assessment of the Worry About Pain Questionnaire." European journal of pain (London, England) 21, no. 7 (August 2017): 1154-1164.

PMID
28230331
Full Text

Porter, LS, Keefe, FJ, Baucom, DH, Olsen, M, Zafar, SY, and Uronis, H. "A randomized pilot trial of a videoconference couples communication intervention for advanced GI cancer." Psycho-oncology 26, no. 7 (July 2017): 1027-1035.

PMID
28691761
Full Text

Gerhart, JI, Burns, JW, Post, KM, Smith, DA, Porter, LS, Burgess, HJ, Schuster, E, Buvanendran, A, Fras, AM, and Keefe, FJ. "Relationships Between Sleep Quality and Pain-Related Factors for People with Chronic Low Back Pain: Tests of Reciprocal and Time of Day Effects." Annals of behavioral medicine : a publication of the Society of Behavioral Medicine 51, no. 3 (June 2017): 365-375.

PMID
27844327
Full Text

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