Francis Joseph Keefe, PhD

Professor in Psychiatry and Behavioral Sciences
Professor in Psychology andNeuroscience
Professor in Anesthesiology
Professor in Medicine
Member of the Duke Cancer Institute
Campus mail 2200 W Main St, Suite 340, Durham, NC 27705
Phone (919) 416-3400
Email address keefe003@mc.duke.edu

The primary aim of our research over the past year has been to evaluate the efficacy of cognitive-behavioral treatments for arthritis pain. We are conducting two treatment outcome studies supported by grants from the National Institute of Arthritis, Musculoskeletal, and Skin Diseases. The first project, conducted with osteoarthritis patients, seeks to determine whether aerobic exercise training can enhance the effects of a cognitive behavior therapy (CBT) intervention for managing pain and disability. The CBT intervention is innovative in that it systematically involves spouses in training in pain coping skills. The second project, tests the long-term effectiveness of a relapse prevention training intervention. This study will feature the use of newly developed daily study methods to analyze the long-term effects of pain coping skills training on daily pain.

In addition, in conjunction with Lara Schanberg of the Department of Medicine we are carrying out a study funded by the Arthritis Foundation that examines the effects of a pain coping skills training regimen for pediatric fibromyalgia patients.

Finally, we are currently gathering pilot data for two new research projects. One project seeks to evaluate the efficacy of a cognitive behavior theapy and education intervention for managing pain in patients having breast cancer and prostate cancer. The second project examines the efficacy of patient controlled compression protocol in the management of pain during mammography.

Education and Training

  • Ph.D., Ohio State University, 1975
  • M.S., Ohio State University, 1973
  • B.A., Bowdoin College, 1971

Publications

Whitney, CA, Dorfman, CS, Shelby, RA, Keefe, FJ, Gandhi, V, and Somers, TJ. "Reminders of cancer risk and pain catastrophizing: relationships with cancer worry and perceived risk in women with a first-degree relative with breast cancer." Familial Cancer 18, no. 1 (January 2019): 9-18.

PMID
29679190
Full Text

Sitlinger, A, Shelby, RA, Van Denburg, AN, White, H, Edmond, SN, Marcom, PK, Bosworth, HB, Keefe, FJ, and Kimmick, GG. "Higher symptom burden is associated with lower function in women taking adjuvant endocrine therapy for breast cancer." Journal of Geriatric Oncology (December 13, 2018).

PMID
30553719
Full Text

Burns, JW, Gerhart, J, Post, KM, Smith, DA, Porter, LS, Buvanendran, A, Fras, AM, and Keefe, FJ. "Spouse Criticism/Hostility Toward Partners With Chronic Pain: The Role of Spouse Attributions for Patient Control Over Pain Behaviors." The Journal of Pain : Official Journal of the American Pain Society 19, no. 11 (November 2018): 1308-1317.

PMID
29864506
Full Text

Cole, LJ, Bennell, KL, Ahamed, Y, Bryant, C, Keefe, F, Moseley, GL, Hodges, P, and Farrell, MJ. "Determining Brain Mechanisms that Underpin Analgesia Induced by the Use of Pain Coping Skills." Pain Medicine (Malden, Mass.) 19, no. 11 (November 2018): 2177-2190.

PMID
29462464
Full Text

Allen, KD, Arbeeva, L, Cené, CW, Coffman, CJ, Grimm, KF, Haley, E, Keefe, FJ, Nagle, CT, Oddone, EZ, Somers, TJ, Watkins, Y, and Campbell, LC. "Pain coping skills training for African Americans with osteoarthritis study: baseline participant characteristics and comparison to prior studies." Bmc Musculoskeletal Disorders 19, no. 1 (September 19, 2018): 337-null.

PMID
30227841
Full Text

Van Denburg, AN, Shelby, RA, Caldwell, DS, O'Sullivan, ML, and Keefe, FJ. "Self-Efficacy for Pain Communication Moderates the Relation Between Ambivalence Over Emotional Expression and Pain Catastrophizing Among Patients With Osteoarthritis." The Journal of Pain : Official Journal of the American Pain Society 19, no. 9 (September 2018): 1006-1014.

PMID
29631037
Full Text

Bennell, KL, Nelligan, RK, Rini, C, Keefe, FJ, Kasza, J, French, S, Forbes, A, Dobson, F, Abbott, JH, Dalwood, A, Harris, A, Vicenzino, B, Hodges, PW, and Hinman, RS. "Effects of internet-based pain coping skills training before home exercise for individuals with hip osteoarthritis (HOPE trial): a randomised controlled trial." Pain 159, no. 9 (September 2018): 1833-1842.

PMID
29794609
Full Text

Cook, CE, George, SZ, and Keefe, F. "Different interventions, same outcomes? Here are four good reasons." British Journal of Sports Medicine 52, no. 15 (August 2018): 951-952.

PMID
29449207
Full Text

Parmelee, PA, Scicolone, MA, Cox, BS, DeCaro, JA, Keefe, FJ, and Smith, DM. "Global Versus Momentary Osteoarthritis Pain and Emotional Distress: Emotional Intelligence as Moderator." Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine 52, no. 8 (July 2018): 713-723.

PMID
30010708
Full Text

Lawford, BJ, Hinman, RS, Kasza, J, Nelligan, R, Keefe, F, Rini, C, and Bennell, KL. "Moderators of effects of internet-delivered exercise and pain coping skills training for people with knee osteoarthritis: Exploratory analysis of the impact randomized controlled trial." Journal of Medical Internet Research 20, no. 5 (May 1, 2018).

Full Text

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