Francis Joseph Keefe, PhD

Professor in Psychiatry and Behavioral Sciences
Professor in Psychology andNeuroscience
Professor in Anesthesiology
Professor in Medicine
Member of the Duke Cancer Institute
Campus mail 2200 W Main St, Suite 340, Durham, NC 27705
Phone (919) 416-3400
Email address keefe003@mc.duke.edu

The primary aim of our research over the past year has been to evaluate the efficacy of cognitive-behavioral treatments for arthritis pain. We are conducting two treatment outcome studies supported by grants from the National Institute of Arthritis, Musculoskeletal, and Skin Diseases. The first project, conducted with osteoarthritis patients, seeks to determine whether aerobic exercise training can enhance the effects of a cognitive behavior therapy (CBT) intervention for managing pain and disability. The CBT intervention is innovative in that it systematically involves spouses in training in pain coping skills. The second project, tests the long-term effectiveness of a relapse prevention training intervention. This study will feature the use of newly developed daily study methods to analyze the long-term effects of pain coping skills training on daily pain.

In addition, in conjunction with Lara Schanberg of the Department of Medicine we are carrying out a study funded by the Arthritis Foundation that examines the effects of a pain coping skills training regimen for pediatric fibromyalgia patients.

Finally, we are currently gathering pilot data for two new research projects. One project seeks to evaluate the efficacy of a cognitive behavior theapy and education intervention for managing pain in patients having breast cancer and prostate cancer. The second project examines the efficacy of patient controlled compression protocol in the management of pain during mammography.

Education and Training

  • Ph.D., Ohio State University, 1975
  • M.S., Ohio State University, 1973
  • B.A., Bowdoin College, 1971

Publications

O'Sullivan, ML, Shelby, RA, Dorfman, CS, Kelleher, SA, Fisher, HM, Rowe Nichols, KA, Keefe, FJ, Sung, AD, and Somers, TJ. "The effect of pre-transplant pain and chronic disease self-efficacy on quality of life domains in the year following hematopoietic stem cell transplantation." Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (November 9, 2017).

PMID
29124418
Full Text

Lefebvre, JC, Jensen, MP, Waters, SJ, Molton, IR, Keefe, FJ, and Caldwell, DS. "The development and assessment of the Worry About Pain Questionnaire." European journal of pain (London, England) 21, no. 7 (August 2017): 1154-1164.

PMID
28230331
Full Text

Porter, LS, Keefe, FJ, Baucom, DH, Olsen, M, Zafar, SY, and Uronis, H. "A randomized pilot trial of a videoconference couples communication intervention for advanced GI cancer." Psycho-oncology 26, no. 7 (July 2017): 1027-1035.

PMID
28691761
Full Text

Gerhart, JI, Burns, JW, Post, KM, Smith, DA, Porter, LS, Burgess, HJ, Schuster, E, Buvanendran, A, Fras, AM, and Keefe, FJ. "Relationships Between Sleep Quality and Pain-Related Factors for People with Chronic Low Back Pain: Tests of Reciprocal and Time of Day Effects." Annals of behavioral medicine : a publication of the Society of Behavioral Medicine 51, no. 3 (June 2017): 365-375.

PMID
27844327
Full Text

Parmelee, PA, Cox, BS, DeCaro, JA, Keefe, FJ, and Smith, DM. "Racial/ethnic differences in sleep quality among older adults with osteoarthritis." Sleep health 3, no. 3 (June 2017): 163-169.

PMID
28526253
Full Text

Rini, C, Vu, MB, Lerner, H, Bloom, C, Carda-Auten, J, Wood, WA, Basch, EM, Voorhees, PM, Reeder-Hayes, KE, and Keefe, FJ. "A qualitative study of patient and provider perspectives on using web-based pain coping skills training to treat persistent cancer pain." Palliative & supportive care (March 7, 2017): 1-15.

PMID
28264744
Full Text

Edmond, SN, Shelby, RA, Keefe, FJ, Fisher, HM, Schmidt, JE, Soo, MS, Skinner, CS, Ahrendt, GM, Manculich, J, Sumkin, JH, Zuley, ML, and Bovbjerg, DH. "Persistent Breast Pain Among Women With Histories of Breast-conserving Surgery for Breast Cancer Compared With Women Without Histories of Breast Surgery or Cancer." The Clinical journal of pain 33, no. 1 (January 2017): 51-56.

PMID
27922843
Full Text

Balderson, BH, McCurry, SM, Vitiello, MV, Shortreed, SM, Rybarczyk, BD, Keefe, FJ, and Korff, MV. "Information without Implementation: A Practical Example for Developing a Best Practice Education Control Group." Behavioral sleep medicine 14, no. 5 (September 2016): 514-527.

PMID
26485203
Full Text

Huebner, JL, Landerman, LR, Somers, TJ, Keefe, FJ, Guilak, F, Blumenthal, JA, Caldwell, DS, and Kraus, VB. "Exploratory secondary analyses of a cognitive-behavioral intervention for knee osteoarthritis demonstrate reduction in biomarkers of adipocyte inflammation." Osteoarthritis and cartilage 24, no. 9 (September 2016): 1528-1534.

PMID
27090577
Full Text

Broderick, JE, Keefe, FJ, Schneider, S, Junghaenel, DU, Bruckenthal, P, Schwartz, JE, Kaell, AT, Caldwell, DS, McKee, D, and Gould, E. "Cognitive behavioral therapy for chronic pain is effective, but for whom?." Pain 157, no. 9 (September 2016): 2115-2123.

PMID
27227692
Full Text

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