Geoffrey Steven Ginsburg, MD, PhD

Professor of Medicine
Director of Duke Center for Applied Genomics and Precision Medicine
Professor in Pathology
Professor of Biostatistics and Bioinformatics
Professor in the School of Nursing
Member of the Duke Cancer Institute
Campus mail 101 Science Dr, Rm 2111, CIEMAS Bldg, Durham, NC 27708
Phone (919) 668-6210

Dr. Geoffrey S. Ginsburg's research interests are in the development of novel paradigms for developing and translating genomic information into medical practice and the integration of personalized medicine into health care.

Education and Training

  • Research Fellow in Cardiology, Medicine, Children's Hospital Boston, 1987 - 1990
  • Fellow in Cardiology, Medicine, Beth Israel Deaconess Medical Center, 1987 - 1990
  • Medical Resident, Medicine, Beth Israel Deaconess Medical Center, 1984 - 1987
  • Ph.D., Boston University, 1984
  • M.D., Boston University, 1984

Publications

Sharma, Abhinav, James L. Januzzi, Sunil Suchindran, Adrian Coles, Udo Hoffmann, Maros Ferencik, Manesh R. Patel, Geoffrey S. Ginsburg, and Pamela S. Douglas. “Utility of High-Sensitivity Troponin Among Stable Patients With Chest Pain Undergoing Stress Imaging (from PROMISE).” Am J Cardiol, August 25, 2021. https://doi.org/10.1016/j.amjcard.2021.07.032.

PMID
34454709
Full Text

Chen, Lingye, Bryan D. Kraft, Victor L. Roggli, Zachary R. Healy, Christopher W. Woods, Ephraim L. Tsalik, Geoffrey S. Ginsburg, et al. “Heparin-based blood purification attenuates organ injury in baboons with Streptococcus pneumoniae pneumonia.” Am J Physiol Lung Cell Mol Physiol 321, no. 2 (August 1, 2021): L321–35. https://doi.org/10.1152/ajplung.00337.2020.

PMID
34105359
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She, Xichen, Yaya Zhai, Ricardo Henao, Christopher W. Woods, Christopher Chiu, Geoffrey S. Ginsburg, Peter X. K. Song, and Alfred O. Hero. “Adaptive Multi-Channel Event Segmentation and Feature Extraction for Monitoring Health Outcomes.” Ieee Trans Biomed Eng 68, no. 8 (August 2021): 2377–88. https://doi.org/10.1109/TBME.2020.3038652.

PMID
33201806
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Sperber, Nina R., Olivia M. Dong, Megan C. Roberts, Paul Dexter, Amanda R. Elsey, Geoffrey S. Ginsburg, Carol R. Horowitz, et al. “Strategies to Integrate Genomic Medicine into Clinical Care: Evidence from the IGNITE Network.” J Pers Med 11, no. 7 (July 8, 2021). https://doi.org/10.3390/jpm11070647.

PMID
34357114
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Steinbrink, Julie M., Rachel A. Myers, Kaiyuan Hua, Melissa D. Johnson, Jessica L. Seidelman, Ephraim L. Tsalik, Ricardo Henao, et al. “The host transcriptional response to Candidemia is dominated by neutrophil activation and heme biosynthesis and supports novel diagnostic approaches.” Genome Med 13, no. 1 (July 5, 2021): 108. https://doi.org/10.1186/s13073-021-00924-9.

PMID
34225776
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Bylstra, Yasmin, Weng Khong Lim, Sylvia Kam, Koei Wan Tham, R Ryanne Wu, Jing Xian Teo, Sonia Davila, et al. “Correction to: Family history assessment significantly enhances delivery of precision medicine in the genomics era.” Genome Med 13, no. 1 (July 5, 2021): 109. https://doi.org/10.1186/s13073-021-00916-9.

PMID
34225778
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Meyersohn, Nandini M., Thomas Mayrhofer, Kathleen E. Corey, Daniel O. Bittner, Pedro V. Staziaki, Balint Szilveszter, Travis Hallett, et al. “Association of Hepatic Steatosis With Major Adverse Cardiovascular Events, Independent of Coronary Artery Disease.” Clin Gastroenterol Hepatol 19, no. 7 (July 2021): 1480-1488.e14. https://doi.org/10.1016/j.cgh.2020.07.030.

PMID
32707340
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Ginsburg, Geoffrey S., Larisa H. Cavallari, Hrishikesh Chakraborty, Rhonda M. Cooper-DeHoff, Paul R. Dexter, Michael T. Eadon, Bart S. Ferket, et al. “Establishing the value of genomics in medicine: the IGNITE Pragmatic Trials Network.” Genet Med 23, no. 7 (July 2021): 1185–91. https://doi.org/10.1038/s41436-021-01118-9.

PMID
33782552
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Wang, Liuyang, Thomas J. Balmat, Alejandro L. Antonia, Florica J. Constantine, Ricardo Henao, Thomas W. Burke, Andy Ingham, et al. “An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility.” Genome Med 13, no. 1 (May 17, 2021): 83. https://doi.org/10.1186/s13073-021-00904-z.

PMID
34001247
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Tsalik, Ephraim L., Ricardo Henao, Jesse L. Montgomery, Jeff W. Nawrocki, Mert Aydin, Emily C. Lydon, Emily R. Ko, et al. “Discriminating Bacterial and Viral Infection Using a Rapid Host Gene Expression Test.” Crit Care Med, April 28, 2021. https://doi.org/10.1097/CCM.0000000000005085.

PMID
33938716
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Pages