Cardiology

Geoffrey Steven Ginsburg, MD, PhD

Professor of Medicine
Director of Duke Center for Applied Genomics and Precision Medicine
Professor in Pathology
Professor in the School of Nursing
Member of the Duke Cancer Institute
Campus mail 101 Science Dr, Rm 2111, CIEMAS Bldg, Durham, NC 27708
Phone (919) 668-6210

Dr. Geoffrey S. Ginsburg's research interests are in the development of novel paradigms for developing and translating genomic information into medical practice and the integration of personalized medicine into health care.

Education and Training

  • Research Fellow in Cardiology, Medicine, Children's Hospital Boston, 1987 - 1990
  • Fellow in Cardiology, Medicine, Beth Israel Deaconess Medical Center, 1987 - 1990
  • Medical Resident, Medicine, Beth Israel Deaconess Medical Center, 1984 - 1987
  • Ph.D., Boston University, 1984
  • M.D., Boston University, 1984

Grants

Publications

Wang, Liuyang, Thomas J. Balmat, Alejandro L. Antonia, Florica J. Constantine, Ricardo Henao, Thomas W. Burke, Andy Ingham, et al. “An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility.” Genome Med 13, no. 1 (May 17, 2021): 83. https://doi.org/10.1186/s13073-021-00904-z.

PMID
34001247
Full Text

Kammerlander, Andreas A., Thomas Mayrhofer, Maros Ferencik, Neha J. Pagidipati, Julia Karady, Geoffrey S. Ginsburg, Michael T. Lu, et al. “Association of Metabolic Phenotypes With Coronary Artery Disease and Cardiovascular Events in Patients With Stable Chest Pain.” Diabetes Care 44, no. 4 (April 2021): 1038–45. https://doi.org/10.2337/dc20-1760.

PMID
33558267
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Ginsburg, Geoffrey S., Larisa H. Cavallari, Hrishikesh Chakraborty, Rhonda M. Cooper-DeHoff, Paul R. Dexter, Michael T. Eadon, Bart S. Ferket, et al. “Establishing the value of genomics in medicine: the IGNITE Pragmatic Trials Network.” Genetics in Medicine : Official Journal of the American College of Medical Genetics, March 29, 2021. https://doi.org/10.1038/s41436-021-01118-9.

PMID
33782552
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Fung, Si Ming, R Ryanne Wu, Rachel A. Myers, Jasper Goh, Geoffrey S. Ginsburg, David Matchar, Lori A. Orlando, and Joanne Ngeow. “Clinical implementation of an oncology-specific family health history risk assessment tool.” Hered Cancer Clin Pract 19, no. 1 (March 20, 2021): 20. https://doi.org/10.1186/s13053-021-00177-y.

PMID
33743786
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McClain, Micah T., Florica J. Constantine, Bradly P. Nicholson, Marshall Nichols, Thomas W. Burke, Ricardo Henao, Daphne C. Jones, et al. “A blood-based host gene expression assay for early detection of respiratory viral infection: an index-cluster prospective cohort study.” Lancet Infect Dis 21, no. 3 (March 2021): 396–404. https://doi.org/10.1016/S1473-3099(20)30486-2.

PMID
32979932
Full Text

McClain, Micah T., Florica J. Constantine, Ricardo Henao, Yiling Liu, Ephraim L. Tsalik, Thomas W. Burke, Julie M. Steinbrink, et al. “Dysregulated transcriptional responses to SARS-CoV-2 in the periphery.” Nat Commun 12, no. 1 (February 17, 2021): 1079. https://doi.org/10.1038/s41467-021-21289-y.

PMID
33597532
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Infeld, Margaret, Kevin A. Friede, Tan Ru San, Holly J. Knickerbocker, Geoffrey S. Ginsburg, Thomas L. Ortel, and Deepak Voora. “Platelet reactivity in response to aspirin and ticagrelor in African-Americans and European-Americans.” J Thromb Thrombolysis 51, no. 2 (February 2021): 249–59. https://doi.org/10.1007/s11239-020-02327-w.

PMID
33159252
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Mahle, Rachael E., Sunil Suchindran, Ricardo Henao, Julie M. Steinbrink, Thomas W. Burke, Micah T. McClain, Geoffrey S. Ginsburg, Christopher W. Woods, and Ephraim L. Tsalik. “Validation of a host gene expression test for bacterial/viral discrimination in immunocompromised hosts.” Clin Infect Dis, January 19, 2021. https://doi.org/10.1093/cid/ciab043.

PMID
33462581
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Bylstra, Yasmin, Weng Khong Lim, Sylvia Kam, Koei Wan Tham, R Ryanne Wu, Jing Xian Teo, Sonia Davila, et al. “Family history assessment significantly enhances delivery of precision medicine in the genomics era.” Genome Med 13, no. 1 (January 7, 2021): 3. https://doi.org/10.1186/s13073-020-00819-1.

PMID
33413596
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