Gordon Ralph Corey, MD

Professor of Medicine
Gary Hock Professor in Global Health, in the School of Medicine
Vice-Chair for Education and Global Health in the Department of Medicine
Research Professor of Global Health
Professor of Pathology
Member in the Duke Clinical Research Institute
Campus mail 310 Trent Drive Room 235 Trent, Box 90519, Durham, NC 27708
Phone (919) 668-7174
Email address corey001@mc.duke.edu

My research is based at the Duke Clinical Research Institute, a large academic clinical research organization designed to conduct clinical trials from small local studies to worldwide trials. The focus of my research is bacterial infections: complicated skin and skin structure infections; postoperative wound infections; hospital-acquired and ventilator-associated pneumonia; bacteremia; and endocarditis. Many of these trials are conducted in concert with the pharmaceutical industry in order to register new antibiotics. In addition, as director of infectious diseases at the DCRI I oversee the work of the mycology group, and tuberculosis trials. This work also includes work supported by NIH grants including sepsis trials, the Staph Aureus and Staph Epi Bacteremia Groups, and the International Collaboration of Endocarditis. The team of investigators with whom I work is highly experienced, amazingly productive and wonderfully collegial.

As a result of my longstanding interest in tropical medicine and the generosity of my patients as well as the Hubert Family we have been able to establish the Hubert-Yeargan Center for Global Health. As a result we have developed a medical center-wide fellowship in Global Health. I am presently the Director of the Center and the Gary Hock Distinguished Professor of Global Health.

Education and Training

  • Fellowship, Infectious Diseases, Duke University School of Medicine, 1978 - 1980
  • Chief Resident, General Internal Medicine, Duke University School of Medicine, 1977 - 1978
  • Residency, General Internal Medicine, Duke University School of Medicine, 1975 - 1977
  • Internship, General Internal Medicine, Duke University School of Medicine, 1974 - 1975
  • M.D., Baylor University, 1973

Publications

Corey, G Ralph, Mark H. Wilcox, George H. Talbot, Dirk Thye, David Friedland, Tanya Baculik, and Tanya CANVAS 1 investigators. “CANVAS 1: the first Phase III, randomized, double-blind study evaluating ceftaroline fosamil for the treatment of patients with complicated skin and skin structure infections..” J Antimicrob Chemother 65 Suppl 4 (November 2010): iv41–51. https://doi.org/10.1093/jac/dkq254.

PMID
21115454
Full Text

Wilcox, Mark H., G Ralph Corey, George H. Talbot, Dirk Thye, David Friedland, Tanya Baculik, and Tanya CANVAS 2 investigators. “CANVAS 2: the second Phase III, randomized, double-blind study evaluating ceftaroline fosamil for the treatment of patients with complicated skin and skin structure infections..” J Antimicrob Chemother 65 Suppl 4 (November 2010): iv53–65. https://doi.org/10.1093/jac/dkq255.

PMID
21115455
Full Text

Kanafani, Zeina, Helen Boucher, Vance Fowler, Christopher Cabell, Bruno Hoen, José M. Miró, Tahaniyat Lalani, et al. “Daptomycin compared to standard therapy for the treatment of native valve endocarditis..” Enferm Infecc Microbiol Clin 28, no. 8 (October 2010): 498–503. https://doi.org/10.1016/j.eimc.2009.07.015.

PMID
20188444
Full Text

Corey, G Ralph, Mark Wilcox, George H. Talbot, H David Friedland, Tanya Baculik, Gary W. Witherell, Ian Critchley, Anita F. Das, and Dirk Thye. “Integrated analysis of CANVAS 1 and 2: phase 3, multicenter, randomized, double-blind studies to evaluate the safety and efficacy of ceftaroline versus vancomycin plus aztreonam in complicated skin and skin-structure infection..” Clin Infect Dis 51, no. 6 (September 15, 2010): 641–50. https://doi.org/10.1086/655827.

PMID
20695801
Full Text

Bennett-Guerrero, Elliott, Theodore N. Pappas, Walter A. Koltun, James W. Fleshman, Min Lin, Jyotsna Garg, Daniel B. Mark, et al. “Gentamicin-collagen sponge for infection prophylaxis in colorectal surgery..” N Engl J Med 363, no. 11 (September 9, 2010): 1038–49. https://doi.org/10.1056/NEJMoa1000837.

PMID
20825316
Full Text

Bennett-Guerrero, Elliott, T Bruce Ferguson, Min Lin, Jyotsna Garg, Daniel B. Mark, Vincent A. Scavo, Nicholas Kouchoukos, et al. “Effect of an implantable gentamicin-collagen sponge on sternal wound infections following cardiac surgery: a randomized trial..” Jama 304, no. 7 (August 18, 2010): 755–62. https://doi.org/10.1001/jama.2010.1152.

PMID
20716738
Full Text

Nannini, Esteban C., Martin E. Stryjewski, and G Ralph Corey. “Ceftaroline for complicated skin and skin-structure infections..” Expert Opin Pharmacother 11, no. 7 (May 2010): 1197–1206. https://doi.org/10.1517/14656561003777026.

PMID
20402556
Full Text

Nannini, Esteban C., Martin E. Stryjewski, Kavindra V. Singh, Tom H. Rude, G Ralph Corey, Vance G. Fowler, and Barbara E. Murray. “Determination of an inoculum effect with various cephalosporins among clinical isolates of methicillin-susceptible Staphylococcus aureus..” Antimicrob Agents Chemother 54, no. 5 (May 2010): 2206–8. https://doi.org/10.1128/AAC.01325-09.

PMID
20211890
Full Text

Lalani, Tahaniyat, Christopher H. Cabell, Daniel K. Benjamin, Ovidiu Lasca, Christoph Naber, Vance G. Fowler, G Ralph Corey, et al. “Analysis of the impact of early surgery on in-hospital mortality of native valve endocarditis: use of propensity score and instrumental variable methods to adjust for treatment-selection bias..” Circulation 121, no. 8 (March 2, 2010): 1005–13. https://doi.org/10.1161/CIRCULATIONAHA.109.864488.

PMID
20159831
Full Text

Nannini, Esteban C., Martin E. Stryjewski, and G Ralph Corey. “Telavancin's interactions with the bacterial cell membrane..” Future Microbiol 5, no. 3 (March 2010): 355–58. https://doi.org/10.2217/fmb.09.122.

PMID
20210546
Full Text

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