Gowthami Morey Arepally, MD

Professor of Medicine
Associate Professor of Pathology
Professor of Pathology
Campus mail Duke Box 3486, Durham, NC 27710
Phone (919) 668-3696
Email address arepa001@mc.duke.edu

Gowthami M. Arepally, M.D. is a Professor of Medicine in the Division of Hematology at Duke University Medical Center and the Medical Director of Therapeutic Apheresis at Duke.  Her clinical interests are in immune thrombocytopenias, thrombotic disorders, and applications of therapeutic apheresis for immunologic disorders.    Dr. Arepally’s long-standing research program investigates immunoregulatory mechanisms in HIT.  Current laboratory efforts focus on the role of complement activation in the immune pathogenesis of HIT, investigations of protamine/heparin antibodies and development of murine models for studies of the HIT immune response.  Clinical projects include applications of therapeutic apheresis, including development of a multi-site network for investigations of thrombotic microangiopathy.

Education and Training

  • Fellow in Hematology-Oncology, Medicine, University of Pennsylvania, 1993 - 1997
  • Chief Medical Resident, Medicine, Emory University, 1992 - 1993
  • Medical Resident, Medicine, Emory University, 1989 - 1992
  • M.D., Vanderbilt University, 1989

Publications

Lee, GM, and Arepally, GM. "Diagnosis and management of heparin-induced thrombocytopenia." Hematology/oncology clinics of North America 27, no. 3 (June 2013): 541-563. (Review)

PMID
23714311
Full Text

Cuker, A, Rux, AH, Hinds, JL, Dela Cruz, M, Yarovoi, SV, Brown, IAM, Yang, W, Konkle, BA, Arepally, GM, Watson, SP, Cines, DB, and Sachais, BS. "Novel diagnostic assays for heparin-induced thrombocytopenia." Blood 121, no. 18 (May 2, 2013): 3727-3732.

PMID
23446735
Full Text

Cuker, A, Rux, AH, Hinds, JL, Dela Cruz, M, Yarovoi, SV, Brown, IAM, Yang, W, Konkle, BA, Arepally, GM, Watson, SP, Cines, DB, and Sachais, BS. "Novel diagnostic assays for heparin-induced thrombocytopenia." BLOOD 121, no. 18 (May 2, 2013): 3727-3732.

Full Text

Lee, GM, Welsby, IJ, Phillips-Bute, B, Ortel, TL, and Arepally, GM. "High incidence of antibodies to protamine and protamine/heparin complexes in patients undergoing cardiopulmonary bypass." Blood 121, no. 15 (April 2013): 2828-2835.

PMID
23422751
Full Text

Zheng, Y, Yu, M, Podd, A, Yuan, L, Newman, DK, Wen, R, Arepally, G, and Wang, D. "Critical role for mouse marginal zone B cells in PF4/heparin antibody production." Blood 121, no. 17 (April 2013): 3484-3492.

PMID
23460609
Full Text

Lee, GM, and Arepally, GM. "Diagnosis and management of heparin-induced thrombocytopenia." Hematology/Oncology Clinics of North America 27, no. 3 (2013): 541-563.

Full Text

Lee, GM, and Arepally, GM. "Heparin-induced thrombocytopenia." Hematology. American Society of Hematology. Education Program 2013 (January 2013): 668-674. (Review)

PMID
24319250
Full Text

Lee, GM, Welsby, I, Bute, BP, Ortel, TL, and Arepally, GM. "High Incidence of Antibodies to Protamine and Protamine/Heparin Complexes in Patients Undergoing Cardiopulmonary Bypass." November 16, 2012.

Scholars@Duke

Lee, GM, Welsby, I, Bute, BP, Ortel, TL, and Arepally, GM. "High Incidence of Antibodies to Protamine and Protamine/Heparin Complexes in Patients Undergoing Cardiopulmonary Bypass." November 16, 2012.

Scholars@Duke

Espinasse, B, Joglekar, M, Valiente, G, and Arepally, GM. "Novel Techniques for Measurement of Variable Sized PF4/H Complexes." November 16, 2012.

Scholars@Duke

Pages