Education and Training
- Ph.D., Engelhardt Institute of Molecular Biology, Russian Academy of Sciences (Russia), 2002
Doridot, Ludivine, Sarah A. Hannou, Sarah A. Krawczyk, Wenxin Tong, Mi-Sung Kim, Gregory S. McElroy, Alan J. Fowler, Inna I. Astapova, and Mark A. Herman. “A Systems Approach Dissociates Fructose-Induced Liver Triglyceride from Hypertriglyceridemia and Hyperinsulinemia in Male Mice.” Nutrients 13, no. 10 (October 18, 2021). https://doi.org/10.3390/nu13103642.
Capozzi, Megan E., Reilly W. Coch, Jepchumba Koech, Inna I. Astapova, Jacob B. Wait, Sara E. Encisco, Jonathan D. Douros, et al. “The Limited Role of Glucagon for Ketogenesis During Fasting or in Response to SGLT2 Inhibition.” Diabetes 69, no. 5 (May 2020): 882–92. https://doi.org/10.2337/db19-1216.
DELEYE, Y. A. N. N., J. A. C. O. B. HERRING, KAVAN H. HESS, BRENNAN R. LEININGER, SARAH A. HANNOU, I. N. N. A. ASTAPOVA, MARK A. HERMAN, JEFFERY S. TESSEM, and PHILLIP J. WHITE. “2191-P: PPM1K Regulates ß-Cell Proliferation, Insulin Content, and GSIS.” In Diabetes, Vol. 68. American Diabetes Association, 2019. https://doi.org/10.2337/db19-2191-p.
Freudenthal, Bernard, Samiksha Shetty, Natalie C. Butterfield, John G. Logan, Cho Rong Han, Xuguang Zhu, Inna Astapova, et al. “Genetic and Pharmacological Targeting of Transcriptional Repression in Resistance to Thyroid Hormone Alpha.” Thyroid 29, no. 5 (May 2019): 726–34. https://doi.org/10.1089/thy.2018.0399.
Shimizu, Hiroaki, Yu Lu, Kristen R. Vella, Federico Damilano, Inna Astapova, Izuki Amano, Megan Ritter, et al. “Nuclear corepressor SMRT is a strong regulator of body weight independently of its ability to regulate thyroid hormone action.” Plos One 14, no. 8 (2019): e0220717. https://doi.org/10.1371/journal.pone.0220717.
Bu, Pengcheng, Kai-Yuan Chen, Kun Xiang, Christelle Johnson, Scott B. Crown, Nikolai Rakhilin, Yiwei Ai, et al. “Aldolase B-Mediated Fructose Metabolism Drives Metabolic Reprogramming of Colon Cancer Liver Metastasis.” Cell Metab 27, no. 6 (June 5, 2018): 1249-1262.e4. https://doi.org/10.1016/j.cmet.2018.04.003.
White, Phillip J., Robert W. McGarrah, Paul A. Grimsrud, Shih-Chia Tso, Wen-Hsuan Yang, Jonathan M. Haldeman, Thomas Grenier-Larouche, et al. “The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase.” Cell Metab 27, no. 6 (June 5, 2018): 1281-1293.e7. https://doi.org/10.1016/j.cmet.2018.04.015.
Kim, MiSung, Inna I. Astapova, Sarah N. Flier, Sarah A. Hannou, Ludivine Doridot, Ashot Sargsyan, Henry H. Kou, Alan J. Fowler, Guosheng Liang, and Mark A. Herman. “Intestinal, but not hepatic, ChREBP is required for fructose tolerance.” Jci Insight 2, no. 24 (December 21, 2017). https://doi.org/10.1172/jci.insight.96703.
Mendoza, Arturo, Inna Astapova, Hiroaki Shimizu, Molly R. Gallop, Lujain Al-Sowaimel, SM Dileas MacGowan, Tim Bergmann, et al. “NCoR1-independent mechanism plays a role in the action of the unliganded thyroid hormone receptor.” Proc Natl Acad Sci U S A 114, no. 40 (October 3, 2017): E8458–67. https://doi.org/10.1073/pnas.1706917114.