Education and Training
- Ph.D., Duke University, 1999
Batinic-Haberle, Ines, Artak Tovmasyan, and Ivan Spasojevic. “Mn Porphyrin-Based Redox-Active Drugs: Differential Effects as Cancer Therapeutics and Protectors of Normal Tissue Against Oxidative Injury.” Antioxid Redox Signal 29, no. 16 (December 1, 2018): 1691–1724. https://doi.org/10.1089/ars.2017.7453.
Tovmasyan, Artak, Jacqueline C. Bueno-Janice, Melba C. Jaramillo, Romulo S. Sampaio, Julio S. Reboucas, Natalia Kyui, Ludmil Benov, et al. “Radiation-Mediated Tumor Growth Inhibition Is Significantly Enhanced with Redox-Active Compounds That Cycle with Ascorbate.” Antioxid Redox Signal 29, no. 13 (November 1, 2018): 1196–1214. https://doi.org/10.1089/ars.2017.7218.
Wang, Jiangbo, Robert A. Mook, Xiu-Rong Ren, Qingfu Zhang, Genevieve Jing, Min Lu, Ivan Spasojevic, H Kim Lyerly, David Hsu, and Wei Chen. “Identification of DK419, a potent inhibitor of Wnt/β-catenin signaling and colorectal cancer growth.” Bioorg Med Chem 26, no. 20 (November 1, 2018): 5435–42. https://doi.org/10.1016/j.bmc.2018.09.016.
Il’yasova, Dora, Luigi Fontana, Manjushri Bhapkar, Carl F. Pieper, Ivan Spasojevic, Leanne M. Redman, Sai Krupa Das, Kim M. Huffman, William E. Kraus, and William E. CALERIE Study Investigators. “Effects of 2 years of caloric restriction on oxidative status assessed by urinary F2-isoprostanes: The CALERIE 2 randomized clinical trial.” Aging Cell 17, no. 2 (April 2018). https://doi.org/10.1111/acel.12719.
Cline, John Mark, Greg Dugan, John Daniel Bourland, Donna L. Perry, Joel D. Stitzel, Ashley A. Weaver, Chen Jiang, et al. “Post-Irradiation Treatment with a Superoxide Dismutase Mimic, MnTnHex-2-PyP5+, Mitigates Radiation Injury in the Lungs of Non-Human Primates after Whole-Thorax Exposure to Ionizing Radiation.” Antioxidants (Basel) 7, no. 3 (March 7, 2018). https://doi.org/10.3390/antiox7030040.
Waitkus, Matthew S., Christopher J. Pirozzi, Casey J. Moure, Bill H. Diplas, Landon J. Hansen, Austin B. Carpenter, Rui Yang, et al. “Adaptive Evolution of the GDH2 Allosteric Domain Promotes Gliomagenesis by Resolving IDH1R132H-Induced Metabolic Liabilities.” Cancer Res 78, no. 1 (January 1, 2018): 36–50. https://doi.org/10.1158/0008-5472.CAN-17-1352.
Abaffy, Tatjana, James R. Bain, Michael J. Muehlbauer, Ivan Spasojevic, Shweta Lodha, Elisa Bruguera, Sara K. O’Neal, So Young Kim, and Hiroaki Matsunami. “A Testosterone Metabolite 19-Hydroxyandrostenedione Induces Neuroendocrine Trans-Differentiation of Prostate Cancer Cells via an Ectopic Olfactory Receptor.” Front Oncol 8 (2018): 162. https://doi.org/10.3389/fonc.2018.00162.
Bhattacharyya, Jayanta, Xiu-Rong Ren, Robert A. Mook, Jiangbo Wang, Ivan Spasojevic, Richard T. Premont, Xinghai Li, Ashutosh Chilkoti, and Wei Chen. “Niclosamide-conjugated polypeptide nanoparticles inhibit Wnt signaling and colon cancer growth.” Nanoscale 9, no. 34 (August 31, 2017): 12709–17. https://doi.org/10.1039/c7nr01973d.
Leu, David, Ivan Spasojevic, Huy Nguyen, Brian Deng, Artak Tovmasyan, Tin Weitner, Romulo S. Sampaio, Ines Batinic-Haberle, and Ting-Ting Huang. “CNS bioavailability and radiation protection of normal hippocampal neurogenesis by a lipophilic Mn porphyrin-based superoxide dismutase mimic, MnTnBuOE-2-PyP5.” Redox Biol 12 (August 2017): 864–71. https://doi.org/10.1016/j.redox.2017.04.027.