James Abbruzzese, MD

Professor of Medicine
D. C. I. Professor of Medical Oncology
Chief, Division of Medical Oncology
Member of the Duke Cancer Institute
Campus mail 440 Mudd Building, Box 3406, Durham, NC 27710
Email address james.abbruzzese@duke.edu

My research interests include the clinical study and treatment of pancreatic cancer.

In Their Words

Education and Training

  • Resident, Internal Medicine, Johns Hopkins University School of Medicine, 1979 - 1981
  • Intern, Internal Medicine, Johns Hopkins University School of Medicine, 1978 - 1979
  • M.D., University of Chicago, 1978

Publications

Luo, Y, Wang, D, Abbruzzese, JL, and Lu, W. "Measurement of Reactive Oxygen Species by Fluorescent Probes in Pancreatic Cancer Cells." Methods in Molecular Biology (Clifton, N.J.) 1882 (January 2019): 207-219.

PMID
30378057
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Stephens, SJ, Czito, B, Zhang, X, Duffy, E, Malicki, M, Pitcher, B, Niedzwiecki, D, Abbruzzese, J, Uronis, H, Blobe, G, Blazer, DG, Willett, CG, and Palta, M. "Surgical and Pathologic Outcomes in Patients on a Phase II Trial of Neoadjuvant Chemotherapy and Hypofractionated Image-Guided Intensity Modulated Radiation Therapy (HIGRT) in Resectable and Borderline Resectable Pancreatic Cancer.": Elsevier BV, November 2018.

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Turner, MC, Cerullo, M, Adam, M, Shah, KN, Blazer, DG, Abbruzzese, JL, and Zani, S. "Adjuvant Chemotherapy Should Follow Pancreaticoduodenectomy for Pancreatic Adenocarcinoma, Despite Delays.": Elsevier BV, October 2018.

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Safe, S, Abbruzzese, J, Abdelrahim, M, and Hedrick, E. "Specificity Protein Transcription Factors and Cancer: Opportunities for Drug Development." Cancer Prevention Research (Philadelphia, Pa.) 11, no. 7 (July 2018): 371-382. (Review)

PMID
29545399
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Palta, M, Czito, BG, Duffy, E, Malicki, M, Niedzwiecki, D, Abbruzzese, JL, Uronis, HE, Blobe, GC, Blazer, DG, and Willett, C. "A phase II trial of neoadjuvant gemcitabine/nab-paclitaxel and SBRT for potentially resectable pancreas cancer: An evaluation of acute toxicity.": American Society of Clinical Oncology (ASCO), May 20, 2018.

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Abbruzzese, JL, Andersen, DK, Borrebaeck, CAK, Chari, ST, Costello, E, Cruz-Monserrate, Z, Eibl, G, Engleman, EG, Fisher, WE, Habtezion, A, Kim, SK, Korc, M, Logsdon, C, Lyssiotis, CA, Pandol, SJ, Rustgi, A, Wolfe, BM, Zheng, L, and Powers, AC. "The Interface of Pancreatic Cancer With Diabetes, Obesity, and Inflammation: Research Gaps and Opportunities: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop." Pancreas 47, no. 5 (May 2018): 516-525.

PMID
29702529
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Choe, JH, and Abbruzzese, JL. "Emerging therapeutic targets in pancreatic adenocarcinoma." In Pancreatic Cancer, 1613-1641. April 11, 2018.

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Neoptolemos, JP, Urrutia, R, Abbruzzese, JL, and Büchler, MW. Preface. April 11, 2018.

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Duan, B, Hu, J, Liu, H, Wang, Y, Li, H, Liu, S, Xie, J, Owzar, K, Abbruzzese, J, Hurwitz, H, Gao, H, and Wei, Q. "Genetic variants in the platelet-derived growth factor subunit B gene associated with pancreatic cancer risk." International Journal of Cancer 142, no. 7 (April 2018): 1322-1331.

PMID
29168174
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Berlin, JD, Feng, Y, Catalano, P, Abbruzzese, JL, Philip, PA, McWilliams, RR, Lowy, AM, Benson, AB, and Blackstock, AW. "An Intergroup Randomized Phase II Study of Bevacizumab or Cetuximab in Combination with Gemcitabine and in Combination with Chemoradiation in Patients with Resected Pancreatic Carcinoma: A Trial of the ECOG-ACRIN Cancer Research Group (E2204)." Oncology 94, no. 1 (January 2018): 39-46.

PMID
29040974
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