James Abbruzzese, MD

Professor of Medicine
D. C. I. Professor of Medical Oncology
Chief, Division of Medical Oncology
Member of the Duke Cancer Institute
Campus mail 440 Mudd Building, Box 3406, Durham, NC 27710
Email address james.abbruzzese@duke.edu

My research interests include the clinical study and treatment of pancreatic cancer.

In Their Words

Education and Training

  • Resident, Internal Medicine, Johns Hopkins University School of Medicine, 1979 - 1981
  • Intern, Internal Medicine, Johns Hopkins University School of Medicine, 1978 - 1979
  • M.D., University of Chicago, 1978

Publications

Kaseb, AO, Shah, NN, Hassabo, HM, Morris, JS, Xiao, L, Abaza, YM, Soliman, K, Lee, J-S, Vauthey, J-N, Wallace, M, Aloia, TA, Curley, S, Abbruzzese, JL, and Hassan, MM. "Reassessing hepatocellular carcinoma staging in a changing patient population." Oncology 86, no. 2 (January 8, 2014): 63-71.

PMID
24401634
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Kaseb, AO, Xiao, L, Hassan, MM, Chae, YK, Lee, JS, Vauthey, JN, Krishnan, S, Cheung, S, Hassabo, HM, Aloia, T, Conrad, C, Curley, SA, Vierling, JM, Jalal, P, Raghav, K, Wallace, M, Rashid, A, Abbruzzese, JL, Wolff, RA, and Morris, JS. "Development and validation of insulin-like growth factor-1 score to assess hepatic reserve in hepatocellular carcinoma." Journal of the National Cancer Institute 106, no. 5 (January 1, 2014).

Scholars@Duke

Fisch, MJ, Abbruzzese, JL, and Hong, WK. "Evaluating physician performance in oncology: moneyball becomes impactball." Journal of oncology practice 10, no. 1 (January 2014): 79-81.

PMID
24443736
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Tzeng, C-WD, Tran Cao, HS, Lee, JE, Pisters, PWT, Varadhachary, GR, Wolff, RA, Abbruzzese, JL, Crane, CH, Evans, DB, Wang, H, Abbott, DE, Vauthey, J-N, Aloia, TA, Fleming, JB, and Katz, MHG. "Treatment sequencing for resectable pancreatic cancer: influence of early metastases and surgical complications on multimodality therapy completion and survival." Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract 18, no. 1 (January 2014): 16-24.

PMID
24241967
Full Text

Tzeng, C-WD, Katz, MHG, Fleming, JB, Lee, JE, Pisters, PWT, Holmes, HM, Varadhachary, GR, Wolff, RA, Abbruzzese, JL, Vauthey, J-N, and Aloia, TA. "Morbidity and mortality after pancreaticoduodenectomy in patients with borderline resectable type C clinical classification." Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 18, no. 1 (January 2014): 146-155.

PMID
24129825
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Zenali, M, Overman, MJ, Rashid, A, Broaddus, RB, Wang, H, Katz, MH, Fleming, JB, Abbruzzese, JL, and Wang, H. "Clinicopathologic features and prognosis of duodenal adenocarcinoma and comparison with ampullary and pancreatic ductal adenocarcinoma." Human Pathology 44, no. 12 (December 2013): 2792-2798.

PMID
24139211
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Chatterjee, D, Katz, MH, Rashid, A, Estrella, JS, Wang, H, Varadhachary, GR, Wolff, RA, Lee, JE, Pisters, PW, Abbruzzese, JL, Fleming, JB, and Wang, H. "Pancreatic intraepithelial neoplasia and histological changes in non-neoplastic pancreas associated with neoadjuvant therapy in patients with pancreatic ductal adenocarcinoma." Histopathology 63, no. 6 (December 2013): 841-851.

PMID
24111684
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Abbott, DE, Tzeng, C-WD, Merkow, RP, Cantor, SB, Chang, GJ, Katz, MH, Bentrem, DJ, Bilimoria, KY, Crane, CH, Varadhachary, GR, Abbruzzese, JL, Wolff, RA, Lee, JE, Evans, DB, and Fleming, JB. "The cost-effectiveness of neoadjuvant chemoradiation is superior to a surgery-first approach in the treatment of pancreatic head adenocarcinoma." Annals of surgical oncology 20 Suppl 3 (December 2013): S500-S508.

PMID
23397153
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Hassan, MM, Kaseb, A, Etzel, CJ, El-Serag, H, Spitz, MR, Chang, P, Hale, KS, Liu, M, Rashid, A, Shama, M, Abbruzzese, JL, Loyer, EM, Kaur, H, Hassabo, HM, Vauthey, J-N, Wray, CJ, Hassan, BS, Patt, YZ, Hawk, E, Soliman, KM, and Li, D. "Genetic variation in the PNPLA3 gene and hepatocellular carcinoma in USA: risk and prognosis prediction." Molecular Carcinogenesis 52 Suppl 1 (November 2013): E139-E147.

PMID
23776098
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Stuti, S, Shroff, S, Overman, MJ, Rashid, A, Shroff, RT, Wang, H, Chatterjee, D, Katz, MH, Lee, JE, Wolff, RA, Abbruzzese, JL, Fleming, JB, and Wang, H. "The expression of pten is associated with improved prognosis in patients with ampullary adenocarcinoma after pancreaticoduodenectomy." Archives of Pathology and Laboratory Medicine 137, no. 11 (November 1, 2013): 1619-1626.

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