James Abbruzzese, MD

Professor of Medicine
D. C. I. Distinguished Professor of Medical Oncology
Chief, Division of Medical Oncology
Member of the Duke Cancer Institute
Campus mail 440 Mudd Building, Box 3406, Durham, NC 27710
Email address james.abbruzzese@duke.edu

My research interests include the clinical study and treatment of pancreatic cancer.

In Their Words

Education and Training

  • Resident, Internal Medicine, Johns Hopkins University School of Medicine, 1979 - 1981
  • Intern, Internal Medicine, Johns Hopkins University School of Medicine, 1978 - 1979
  • M.D., The University of Chicago, 1978

Publications

Raghav, Kanwal Pratap Singh, Sminil Mahajan, James C. Yao, Brian P. Hobbs, Donald A. Berry, Rebecca D. Pentz, Alda Tam, et al. “From Protocols to Publications: A Study in Selective Reporting of Outcomes in Randomized Trials in Oncology.” J Clin Oncol 33, no. 31 (November 1, 2015): 3583–90. https://doi.org/10.1200/JCO.2015.62.4148.

PMID
26304898
Full Text

Lu, W., Y. Yang, Y. Luo, Y. Liu, X. Wang, M. Liu, R. A. Wolff, J. L. Abbruzzese, and C. D. Logsdon. “FGF21 Delays Pancreatic Cancer Formation and Prevents Liver Metastasis in Oncogenic Kras Expressing Mice Fed on High-Fat Diet.” Pancreas 44, no. 8 (November 1, 2015): 1393–1393.

Scholars@Duke

Li, Donghui, Mayurika N. Pise, Michael J. Overman, Chang Liu, Hongwei Tang, Saroj Vadhan-Raj, and James L. Abbruzzese. “ABO non-O type as a risk factor for thrombosis in patients with pancreatic cancer.” Cancer Med 4, no. 11 (November 2015): 1651–58. https://doi.org/10.1002/cam4.513.

PMID
26275671
Full Text

Fogelman, David, Elizabeth A. Sugar, George Oliver, Neeraj Shah, Alison Klein, Christine Alewine, Huamin Wang, et al. “Family history as a marker of platinum sensitivity in pancreatic adenocarcinoma.” Cancer Chemotherapy and Pharmacology 76, no. 3 (September 2015): 489–98. https://doi.org/10.1007/s00280-015-2788-6.

PMID
26126726
Full Text

Lu, Weiqin, Yaying Yang, Xiaojie Wang, Yan Liu, Yongde Luo, Robert A. Wolff, James L. Abbruzzese, and Craig D. Logsdon. “Abstract 891: FGF21 prevents high fat diet-induced pancreatic cancer in mice expressing oncogenic Kras.” In Prevention Research. American Association for Cancer Research, 2015. https://doi.org/10.1158/1538-7445.am2015-891.

Full Text

Reddy, S. M., S. Kopetz, J. Morris, N. Parikh, W. Qiao, M. J. Overman, D. Fogelman, et al. “Phase II study of saracatinib (AZD0530) in patients with previously treated metastatic colorectal cancer.” Invest New Drugs 33, no. 4 (August 2015): 977–84. https://doi.org/10.1007/s10637-015-0257-z.

PMID
26062928
Full Text

Zhao, Jun, Chunhui Wu, James Abbruzzese, Rosa F. Hwang, and Chun Li. “Cyclopamine-loaded core-cross-linked polymeric micelles enhance radiation response in pancreatic cancer and pancreatic stellate cells.” Mol Pharm 12, no. 6 (June 1, 2015): 2093–2100. https://doi.org/10.1021/mp500875f.

PMID
25936695
Full Text

Zhang, Tian, Rengasamy Boominathan, Brad Foulk, Mark Carle Connelly, Chandra Rao, Gabor Kemeny, John H. Strickler, et al. “Evaluation of a novel c-MET based circulating tumor cell (CTC) biomarker in patients with gastrointestinal (GI) and genitourinary (GU) malignancies.” In Journal of Clinical Oncology, Vol. 33. AMER SOC CLINICAL ONCOLOGY, 2015.

Scholars@Duke

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