James Abbruzzese, MD

Professor of Medicine
D. C. I. Professor of Medical Oncology
Chief, Division of Medical Oncology
Member of the Duke Cancer Institute
Campus mail 440 Mudd Building, Box 3406, Durham, NC 27710
Email address james.abbruzzese@duke.edu

My research interests include the clinical study and treatment of pancreatic cancer.

In Their Words

Education and Training

  • Resident, Internal Medicine, Johns Hopkins University School of Medicine, 1979 - 1981
  • Intern, Internal Medicine, Johns Hopkins University School of Medicine, 1978 - 1979
  • M.D., University of Chicago, 1978

Publications

Grau, A. M., L. Zhang, W. Wang, S. Ruan, D. B. Evans, J. L. Abbruzzese, W. Zhang, and P. J. Chiao. “Induction of p21waf1 expression and growth inhibition by transforming growth factor beta involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells.” Cancer Res 57, no. 18 (September 15, 1997): 3929–34.

PMID
9307274
Scholars@Duke

Pazdur, R., E. Diaz-Canton, W. P. Ballard, J. E. Bradof, S. Graham, S. G. Arbuck, J. L. Abbruzzese, and R. Winn. “Phase II trial of 9-aminocamptothecin administered as a 72-hour continuous infusion in metastatic colorectal carcinoma.” J Clin Oncol 15, no. 8 (August 1997): 2905–9. https://doi.org/10.1200/JCO.1997.15.8.2905.

PMID
9256134
Full Text

Lenzi, R., K. R. Hess, M. C. Abbruzzese, M. N. Raber, N. G. Ordoñez, and J. L. Abbruzzese. “Poorly differentiated carcinoma and poorly differentiated adenocarcinoma of unknown origin: favorable subsets of patients with unknown-primary carcinoma?” J Clin Oncol 15, no. 5 (May 1997): 2056–66. https://doi.org/10.1200/JCO.1997.15.5.2056.

PMID
9164218
Full Text

Abbruzzese, J. L., D. B. Evans, I. Raijman, L. Larry, T. King, S. D. Leach, and M. L. Frazier. “Detection of mutated c-Ki-ras in the bile of patients with pancreatic cancer.” Anticancer Res 17, no. 2A (March 1997): 795–801.

PMID
9137410
Scholars@Duke

Spitz, F. R., J. L. Abbruzzese, J. E. Lee, P. W. Pisters, A. M. Lowy, C. J. Fenoglio, K. R. Cleary, et al. “Preoperative and postoperative chemoradiation strategies in patients treated with pancreaticoduodenectomy for adenocarcinoma of the pancreas.” J Clin Oncol 15, no. 3 (March 1997): 928–37. https://doi.org/10.1200/JCO.1997.15.3.928.

PMID
9060530
Full Text

Raijman, I., I. Siddique, P. Lynch, Y. Patt, M. Roh, S. Curley, J. Lee, P. Pisters, D. Evans, and J. Abbruzzese. “Endoscopic management of biliary tract cancer with the wallstent: Experience in 121 patients.” Gastrointestinal Endoscopy 45, no. 4 (January 1, 1997). https://doi.org/10.1016/S0016-5107(97)80483-X.

Full Text

Raijman, I., I. Siddique, P. Lynch, Y. Patt, M. Roh, S. Curley, J. Lee, P. Pisters, D. Evans, and J. Abbruzzese. “Comparison between metastatic vs primary biliary tract cancer in their response to the wallstent.” Gastrointestinal Endoscopy 45, no. 4 (January 1, 1997). https://doi.org/10.1016/S0016-5107(97)80482-8.

Full Text

Evans, D. B., J. E. Lee, P. W. Pisters, C. Charnsangavej, L. M. Ellis, P. J. Chiao, R. Lenzi, and J. L. Abbruzzese. “Advances in the diagnosis and treatment of adenocarcinoma of the pancreas.” Cancer Treat Res 90 (1997): 109–25. https://doi.org/10.1007/978-1-4615-6165-1_6.

PMID
9367080
Full Text

Abbruzzese, J. L., D. B. Evans, I. Raijman, L. Larry, T. King, S. D. Leach, and M. L. Frazier. “Detection of mutated c-Ki-ras in the bile of patients with pancreatic cancer.” Anticancer Research 17, no. 2 A (1997): 795–801.

Scholars@Duke

Mason, K. A., N. R. Hunter, M. Milas, J. L. Abbruzzese, and L. Milas. “Docetaxel enhances tumor radioresponse in vivo.” Clinical Cancer Research 3, no. 12 I (1997): 2431–38.

Scholars@Duke

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