James Enlou Tcheng, MD

Professor of Medicine
Assistant Dean for Academic Appointments
Professor of Family Medicine and Community Health
Campus mail Duke Box 2708, Durham, NC 27710
Phone (919) 668-8796
Email address tchen001@mc.duke.edu

In addition to my clinical responsibilities as an interventional cardiologist, my research interests include the study of antithrombotic therapies in cardiovascular disease and biomedical informatics and information technologies.

My research is applied (clinical research), primarily focusing on the evaluation of technologies in the clinical arena.

I have participated in numerous clinical trials and have also conducted several multicenter studies, including the EPIC, PROLOG, EPILOG, EPISTENT, IMPACT, IMPACT II, TOTAL, PRIDE, ESPRIT, MEND-1, and ELECT Trials.

My areas of expertise are an outgrowth of my clinical research, and includes use of the new antiplatelet therapeutics in the treatment of coronary artery disease; treatment of unstable angina and acute myocardial infarction; quality assurance and quality improvement; application of informatics and information technology to the delivery of care; and the application of excimer laser coronary angioplasty in the treatment of coronary artery disease.

Key words: angioplasty, excimer laser, platelet glycoproteins, computers, clinical trials.

Education and Training

  • Fellow, Cardiology, Duke University School of Medicine, 1986 - 1988
  • Resident, Internal Medicine, Barnes Hospital, 1983 - 1985
  • Intern, Internal Medicine, Barnes Hospital, 1982 - 1983
  • M.D., Johns Hopkins University, 1982



Slotwiner, David J., Robert L. Abraham, Sana M. Al-Khatib, H Vernon Anderson, T Jared Bunch, Martha G. Ferrara, Neal Lippman, et al. “HRS White Paper on interoperability of data from cardiac implantable electronic devices (CIEDs)..” Heart Rhythm 16, no. 9 (September 2019): e107–27. https://doi.org/10.1016/j.hrthm.2019.05.002.

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Writing Committee Members, William S., Pamela S. Douglas, Blase A. Carabello, Roberto M. Lang, Leo Lopez, Patricia A. Pellikka, Michael H. Picard, et al. “2019 ACC/AHA/ASE Key Data Elements and Definitions for Transthoracic Echocardiography: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Data Standards (Writing Committee to Develop Clinical Data Standards for Transthoracic Echocardiography) and the American Society of Echocardiography..” J Am Soc Echocardiogr 32, no. 9 (September 2019): 1161–1248. https://doi.org/10.1016/j.echo.2019.05.006.

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Lowenstern, Angela, Jingjing Wu, Steven M. Bradley, Alexander C. Fanaroff, James E. Tcheng, and Tracy Y. Wang. “Current landscape of hybrid revascularization: A report from the NCDR CathPCI Registry..” Am Heart J 215 (September 2019): 167–77. https://doi.org/10.1016/j.ahj.2019.06.014.

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Denardo, Scott J., Keith E. Davis, and James E. Tcheng. “Pursuit of the Optimal Antithrombotic Regimen for Patients With Non-ST-Segment Elevation Acute Coronary Syndrome Who Undergo Subsequent Percutaneous Coronary Intervention..” Am J Cardiol 123, no. 10 (May 15, 2019). https://doi.org/10.1016/j.amjcard.2019.02.036.

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Valentine, C Michael, James E. Tcheng, and Thad Waites. “Translating the Translation: What Clinicians Should Know About the Fourth Universal Definition of Myocardial Infarction..” J Am Coll Cardiol 72, no. 21 (November 27, 2018): 2668–70. https://doi.org/10.1016/j.jacc.2018.10.015.

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Watson, Timothy J., Paul J. L. Ong, and James E. Tcheng. Primary Angioplasty A Practical Guide. Springer, 2018.


Hicks, Karen A., Kenneth W. Mahaffey, Roxana Mehran, Steven E. Nissen, Stephen D. Wiviott, Billy Dunn, Scott D. Solomon, et al. “2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials..” J Am Coll Cardiol 71, no. 9 (March 6, 2018): 1021–34. https://doi.org/10.1016/j.jacc.2017.12.048.

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Hicks, Karen A., Kenneth W. Mahaffey, Roxana Mehran, Steven E. Nissen, Stephen D. Wiviott, Billy Dunn, Scott D. Solomon, et al. “2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials..” Circulation 137, no. 9 (February 27, 2018): 961–72. https://doi.org/10.1161/CIRCULATIONAHA.117.033502.

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Drozda, Joseph P., James Roach, Thomas Forsyth, Paul Helmering, Benjamin Dummitt, and James E. Tcheng. “Constructing the informatics and information technology foundations of a medical device evaluation system: a report from the FDA unique device identifier demonstration..” J Am Med Inform Assoc 25, no. 2 (February 1, 2018): 111–20. https://doi.org/10.1093/jamia/ocx041.

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