James Enlou Tcheng, MD

Professor of Medicine
Professor of Community and Family Medicine
Campus mail Duke Box 2708, Durham, NC 27710
Phone (919) 668-8796
Email address tchen001@mc.duke.edu

In addition to my clinical responsibilities as an interventional cardiologist, my research interests include the study of antithrombotic therapies in cardiovascular disease and biomedical informatics and information technologies.

My research is applied (clinical research), primarily focusing on the evaluation of technologies in the clinical arena.

I have participated in numerous clinical trials and have also conducted several multicenter studies, including the EPIC, PROLOG, EPILOG, EPISTENT, IMPACT, IMPACT II, TOTAL, PRIDE, ESPRIT, MEND-1, and ELECT Trials.

My areas of expertise are an outgrowth of my clinical research, and includes use of the new antiplatelet therapeutics in the treatment of coronary artery disease; treatment of unstable angina and acute myocardial infarction; quality assurance and quality improvement; application of informatics and information technology to the delivery of care; and the application of excimer laser coronary angioplasty in the treatment of coronary artery disease.

Key words: angioplasty, excimer laser, platelet glycoproteins, computers, clinical trials.

Education and Training

  • Fellow, Cardiology, Duke University School of Medicine, 1986 - 1988
  • Resident, Internal Medicine, Barnes Hospital, 1983 - 1985
  • Intern, Internal Medicine, Barnes Hospital, 1982 - 1983
  • M.D., Johns Hopkins University, 1982

Publications

Denardo, SJ, Davis, KE, and Tcheng, JE. "Pursuit of the Optimal Antithrombotic Regimen for Patients With Non-ST-Segment Elevation Acute Coronary Syndrome Who Undergo Subsequent Percutaneous Coronary Intervention." The American Journal of Cardiology 123, no. 10 (May 2019): 1736-null. (Letter)

PMID
30926146
Full Text

Valentine, CM, Tcheng, JE, and Waites, T. "Translating the Translation: What Clinicians Should Know About the Fourth Universal Definition of Myocardial Infarction." Journal of the American College of Cardiology 72, no. 21 (November 2018): 2668-2670.

PMID
30466524
Full Text

Watson, TJ, Ong, PJL, and Tcheng, JE. Primary Angioplasty A Practical Guide.: Springer, July 13, 2018.

Scholars@Duke

Hicks, KA, Mahaffey, KW, Mehran, R, Nissen, SE, Wiviott, SD, Dunn, B, Solomon, SD, Marler, JR, Teerlink, JR, Farb, A, Morrow, DA, Targum, SL, Sila, CA, Thanh Hai, MT, Jaff, MR, Joffe, HV, Cutlip, DE, Desai, AS, Lewis, EF, Gibson, CM, Landray, MJ, Lincoff, AM, White, CJ, Brooks, SS, Rosenfield, K, Domanski, MJ, Lansky, AJ, McMurray, JJV, Tcheng, JE, Steinhubl, SR, Burton, P, Mauri, L, O'Connor, CM, Pfeffer, MA, Hung, HMJ, Stockbridge, NL, Chaitman, BR, Temple, RJ, and Standardized Data Collection for Cardiovascular Trials Initiative (SCTI), . "2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials." Journal of the American College of Cardiology 71, no. 9 (March 2018): 1021-1034. (Review)

PMID
29495982
Full Text

Drozda, JP, Roach, J, Forsyth, T, Helmering, P, Dummitt, B, and Tcheng, JE. "Constructing the informatics and information technology foundations of a medical device evaluation system: a report from the FDA unique device identifier demonstration." Journal of the American Medical Informatics Association : Jamia 25, no. 2 (February 2018): 111-120.

PMID
28472359
Full Text

Jones, WS, Krucoff, MW, Morales, P, Wilgus, RW, Heath, AH, Williams, MF, Tcheng, JE, Marinac-Dabic, JD, Malone, ML, Reed, TL, Fukaya, R, Lookstein, RA, Handa, N, Aronow, HD, Bertges, DJ, Jaff, MR, Tsai, TT, Smale, JA, Zaugg, MJ, Thatcher, RJ, and Cronenwett, JL. "Registry Assessment of Peripheral Interventional Devices (RAPID): Registry assessment of peripheral interventional devices core data elements." Journal of Vascular Surgery 67, no. 2 (February 2018): 637-644.e30.

PMID
29389426
Full Text

Hicks, KA, Mahaffey, KW, Mehran, R, Nissen, SE, Wiviott, SD, Dunn, B, Solomon, SD, Marler, JR, Teerlink, JR, Farb, A, Morrow, DA, Targum, SL, Sila, CA, Hai, MTT, Jaff, MR, Joffe, HV, Cutlip, DE, Desai, AS, Lewis, EF, Gibson, CM, Landray, MJ, Lincoff, AM, White, CJ, Brooks, SS, Rosenfield, K, Domanski, MJ, Lansky, AJ, McMurray, JJV, Tcheng, JE, Steinhubl, SR, Burton, P, Mauri, L, O'Connor, CM, Pfeffer, MA, Hung, HMJ, Stockbridge, NL, Chaitman, BR, Temple, RJ, and Standardized Data Collection for Cardiovascular Trials Initiative (SCTI), . "2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials." Circulation 137, no. 9 (February 2018): 961-972. (Review)

PMID
29483172
Full Text

Jones, WS, Krucoff, MW, Morales, P, Wilgus, RW, Heath, AH, Williams, MF, Tcheng, JE, Marinac-Dabic, JD, Malone, ML, Reed, TL, Fukaya, R, Lookstein, R, Handa, N, Aronow, HD, Bertges, DJ, Jaff, MR, Tsai, TT, Smale, JA, Zaugg, MJ, Thatcher, RJ, and Cronenwett, JL. "Registry Assessment of Peripheral Interventional Devices (RAPID) - Registry Assessment of Peripheral Interventional Devices Core Data Elements." Circulation Journal : Official Journal of the Japanese Circulation Society 82, no. 2 (January 23, 2018): 316-322. (Review)

PMID
29367497
Full Text

O'Connor, CM, Psotka, MA, Fiuzat, M, Lindenfeld, J, Abraham, WT, Bristow, MR, Canos, D, Harrington, RA, Hillebrenner, M, Jessup, M, Malik, FI, Solomon, SD, Stockbridge, N, Tcheng, JE, Unger, EF, Whellan, DJ, Zuckerman, B, and Califf, RM. "Improving Heart Failure Therapeutics Development in the United States: The Heart Failure Collaboratory." Journal of the American College of Cardiology 71, no. 4 (January 2018): 443-453. (Review)

PMID
29389362
Full Text

Reed, TL, Drozda, JP, Baskin, KM, Tcheng, J, Conway, K, Wilson, N, Marinac-Dabic, D, Heise, T, and Krucoff, MW. "Advancing medical device innovation through collaboration and coordination of structured data capture pilots: Report from the Medical Device Epidemiology Network (MDEpiNet) Specific, Measurable, Achievable, Results-Oriented, Time Bound (SMART) Think Tank." Healthcare (Amsterdam, Netherlands) 5, no. 4 (December 2017): 158-164.

PMID
27939170
Full Text

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