James Enlou Tcheng, MD

Professor of Medicine
Professor of Family Medicine and Community Health
Campus mail Duke Box 2708, Durham, NC 27710
Phone (919) 668-8796
Email address tchen001@mc.duke.edu

In addition to my clinical responsibilities as an interventional cardiologist, my research interests include the study of antithrombotic therapies in cardiovascular disease and biomedical informatics and information technologies.

My research is applied (clinical research), primarily focusing on the evaluation of technologies in the clinical arena.

I have participated in numerous clinical trials and have also conducted several multicenter studies, including the EPIC, PROLOG, EPILOG, EPISTENT, IMPACT, IMPACT II, TOTAL, PRIDE, ESPRIT, MEND-1, and ELECT Trials.

My areas of expertise are an outgrowth of my clinical research, and includes use of the new antiplatelet therapeutics in the treatment of coronary artery disease; treatment of unstable angina and acute myocardial infarction; quality assurance and quality improvement; application of informatics and information technology to the delivery of care; and the application of excimer laser coronary angioplasty in the treatment of coronary artery disease.

Key words: angioplasty, excimer laser, platelet glycoproteins, computers, clinical trials.

Education and Training

  • Fellow, Cardiology, Duke University School of Medicine, 1986 - 1988
  • Resident, Internal Medicine, Barnes Hospital, 1983 - 1985
  • Intern, Internal Medicine, Barnes Hospital, 1982 - 1983
  • M.D., Johns Hopkins University, 1982

Publications

Segall, Noa, Jeffrey G. Saville, Pete L’Engle, Boyd Carlson, Melanie C. Wright, Kevin Schulman, and James E. Tcheng. “Usability evaluation of a personal health record..” Amia Annu Symp Proc 2011 (2011): 1233–42.

PMID
22195184
Scholars@Duke

Walden, Anita, Meredith Nahm, M Edwina Barnett, Jose G. Conde, Andrew Dent, Ahmed Fadiel, Theresa Perry, Chris Tolk, James E. Tcheng, and Eric L. Eisenstein. “Economic analysis of centralized vs. decentralized electronic data capture in multi-center clinical studies..” Stud Health Technol Inform 164 (2011): 82–88.

PMID
21335692
Scholars@Duke

Tcheng, James. Primary Angioplasty in Acute Myocardial Infarction. Humana Press, 2010.

Scholars@Duke

Sorajja, Paul, Bernard J. Gersh, David A. Cox, Michael G. McLaughlin, Peter Zimetbaum, Costantino Costantini, Thomas Stuckey, et al. “Impact of delay to angioplasty in patients with acute coronary syndromes undergoing invasive management: analysis from the ACUITY (Acute Catheterization and Urgent Intervention Triage strategY) trial..” J Am Coll Cardiol 55, no. 14 (April 6, 2010): 1416–24. https://doi.org/10.1016/j.jacc.2009.11.063.

PMID
20359590
Full Text

Deibele, Albert J., Lisa K. Jennings, James E. Tcheng, Cathy Neva, Angela D. Earhart, and C Michael Gibson. “Intracoronary eptifibatide bolus administration during percutaneous coronary revascularization for acute coronary syndromes with evaluation of platelet glycoprotein IIb/IIIa receptor occupancy and platelet function: the Intracoronary Eptifibatide (ICE) Trial..” Circulation 121, no. 6 (February 16, 2010): 784–91. https://doi.org/10.1161/CIRCULATIONAHA.109.882746.

PMID
20124127
Full Text

Kruk, Mariusz, Christopher E. Buller, James Enlou Tcheng, Vladimir Dzavík, Venugopal Menon, GB John Mancini, Sandra A. Forman, et al. “Impact of left ventricular ejection fraction on clinical outcomes over five years after infarct-related coronary artery recanalization (from the Occluded Artery Trial [OAT])..” Am J Cardiol 105, no. 1 (January 1, 2010): 10–16. https://doi.org/10.1016/j.amjcard.2009.08.644.

PMID
20102883
Full Text

Tcheng, James E., and David A. Zidar. “Gone but not forgotten: the case for drug-eluting stents in percutaneous revascularization of the chronic coronary total occlusion..” Jacc Cardiovasc Interv 2, no. 12 (December 2009): 1266–68. https://doi.org/10.1016/j.jcin.2009.10.007.

PMID
20129554
Full Text

Rabbani, Leroy E., Srinivas Iyengar, George D. Dangas, Cindy L. Grines, David A. Cox, Eulogio Garcia, James E. Tcheng, et al. “Impact of thienopyridine administration prior to primary stenting in acute myocardial infarction..” J Interv Cardiol 22, no. 4 (August 2009): 378–84. https://doi.org/10.1111/j.1540-8183.2009.00474.x.

PMID
19496901
Full Text

Madan, Mina, Janarthan Nikhil, Anne S. Hellkamp, Karen S. Pieper, Marino Labinaz, E. A. Cohen, Christopher E. Buller, et al. “Effect of operator and institutional volume on clinical outcomes after percutaneous coronary interventions performed in Canada and the United States: a brief report from the Enhanced Suppression of the Platelet glycoprotein IIb/IIIa Receptor with Integrilin Therapy (ESPRIT) study..” Can J Cardiol 25, no. 8 (August 2009): e269–72. https://doi.org/10.1016/s0828-282x(09)70120-5.

PMID
19668787
Full Text

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