James Patrick White, PhD

Assistant Professor in Medicine
Assistant Research Professor in Cell Biology
Member of Duke Molecular Physiology Institute
Senior Fellow in the Center for Study of Aging
Affiliate of the Regeneration Next Initiative
Member of the Duke Cancer Institute
Email address james.white@duke.edu

Education and Training

  • Postdoctoral Fellow, Harvard Medical School, 2011 - 2014
  • Ph.D., University of South Carolina, Columbia, 2010
  • M.S., Florida State University, 2005

Publications

Baht, G. S., A. Bareja, D. E. Lee, R. R. Rao, R. Huang, J. L. Huebner, D. B. Bartlett, et al. “Meteorin-like facilitates skeletal muscle repair through a Stat3/IGF-1 mechanism.” Nature Metabolism 2, no. 3 (March 1, 2020): 278–89. https://doi.org/10.1038/s42255-020-0184-y.

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Colón-Emeric, Cathleen, Heather E. Whitson, Sarah D. Berry, Roger A. Fielding, Denise K. Houston, Douglas P. Kiel, Clifford J. Rosen, et al. “AGS and NIA Bench-to Bedside Conference Summary: Osteoporosis and Soft Tissue (Muscle and Fat) Disorders.” J Am Geriatr Soc 68, no. 1 (January 2020): 31–38. https://doi.org/10.1111/jgs.16248.

PMID
31791114
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Huang, Rong, Xiaohua Zong, Puviindran Nadesan, Janet L. Huebner, Virginia B. Kraus, James P. White, Phillip J. White, and Gurpreet S. Baht. “Lowering circulating apolipoprotein E levels improves aged bone fracture healing.” Jci Insight 4, no. 18 (September 19, 2019). https://doi.org/10.1172/jci.insight.129144.

PMID
31534056
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Bareja, A., D. E. Lee, and J. P. White. “Maximizing Longevity and Healthspan: Multiple Approaches All Converging on Autophagy.” Frontiers in Cell and Developmental Biology 7 (September 6, 2019). https://doi.org/10.3389/fcell.2019.00183.

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Zhou, Jin, Daniel C. Parker, James P. White, Andrea Lim, Kim M. Huffman, Jia Pei Ho, Paul M. Yen, and William E. Kraus. “Thyroid Hormone Status Regulates Skeletal Muscle Response to Chronic Motor Nerve Stimulation.” Front Physiol 10 (2019): 1363. https://doi.org/10.3389/fphys.2019.01363.

PMID
31736784
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Vi, Linda, Gurpreet S. Baht, Erik J. Soderblom, Heather Whetstone, Qingxia Wei, Bridgette Furman, Vijitha Puviindran, et al. “Macrophage cells secrete factors including LRP1 that orchestrate the rejuvenation of bone repair in mice.” Nat Commun 9, no. 1 (December 5, 2018): 5191. https://doi.org/10.1038/s41467-018-07666-0.

PMID
30518764
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White, James P., Andrew N. Billin, Milton E. Campbell, Alan J. Russell, Kim M. Huffman, and William E. Kraus. “The AMPK/p27Kip1 Axis Regulates Autophagy/Apoptosis Decisions in Aged Skeletal Muscle Stem Cells.” Stem Cell Reports 11, no. 2 (August 14, 2018): 425–39. https://doi.org/10.1016/j.stemcr.2018.06.014.

PMID
30033086
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Khandekar, Melin J., Alexander S. Banks, Dina Laznik-Bogoslavski, James P. White, Jang Hyun Choi, Lawrence Kazak, James C. Lo, et al. “Noncanonical agonist PPARγ ligands modulate the response to DNA damage and sensitize cancer cells to cytotoxic chemotherapy.” Proc Natl Acad Sci U S A 115, no. 3 (January 16, 2018): 561–66. https://doi.org/10.1073/pnas.1717776115.

PMID
29295932
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