James Patrick White, PhD

Assistant Professor in Medicine
Member of Duke Molecular Physiology Institute
Senior Fellow in the Center for Study of Aging
Affiliate of the Regeneration Next Initiative
Email address james.white@duke.edu

Education and Training

  • Postdoctoral Fellow, Harvard Medical School, 2011 - 2014
  • Ph.D., University of South Carolina at Columbia, 2010
  • M.S., Florida State University, 2005

Publications

Khandekar, MJ, Banks, AS, Laznik-Bogoslavski, D, White, JP, Choi, JH, Kazak, L, Lo, JC, Cohen, P, Wong, KK, Kamenecka, TM, Griffin, PR, and Spiegelman, BM. "Noncanonical agonist PPARγ ligands modulate the response to DNA damage and sensitize cancer cells to cytotoxic chemotherapy." Proceedings of the National Academy of Sciences of the United States of America 115, no. 3 (January 16, 2018): 561-566.

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White, JP. "IL-6, cancer and cachexia: metabolic dysfunction creates the perfect storm." Translational Cancer Research 6, no. S2 (March 2017): S280-S285.

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White, JP. "Control of Skeletal Muscle Cell Growth and Size Through Adhesion GPCRs (." In Handbook of Experimental Pharmacology: Adhesion G Protein-coupled Receptors, 299-308. Springer, November 9, 2016. (Chapter)

PMID
27832493
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Liebscher, I, Ackley, B, Araç, D, Ariestanti, DM, Aust, G, Bae, B-I, Bista, BR, Bridges, JP, Duman, JG, Engel, FB, Giera, S, Goffinet, AM, Hall, RA, Hamann, J, Hartmann, N, Lin, H-H, Liu, M, Luo, R, Mogha, A, Monk, KR, Peeters, MC, Prömel, S, Ressl, S, Schiöth, HB, Sigoillot, SM, Song, H, Talbot, WS, Tall, GG, White, JP, Wolfrum, U, Xu, L, and Piao, X. "New functions and signaling mechanisms for the class of adhesion G protein-coupled receptors." Annals of the New York Academy of Sciences 1333 (December 2014): 43-64.

PMID
25424900
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White, JP, Wrann, CD, Rao, RR, Nair, SK, Jedrychowski, MP, You, J-S, Martínez-Redondo, V, Gygi, SP, Ruas, JL, Hornberger, TA, Wu, Z, Glass, DJ, Piao, X, and Spiegelman, BM. "G protein-coupled receptor 56 regulates mechanical overload-induced muscle hypertrophy." Proceedings of the National Academy of Sciences of the United States of America 111, no. 44 (November 2014): 15756-15761.

PMID
25336758
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Kir, S, White, JP, Kleiner, S, Kazak, L, Cohen, P, Baracos, VE, and Spiegelman, BM. "Tumour-derived PTH-related protein triggers adipose tissue browning and cancer cachexia." Nature 513, no. 7516 (September 2014): 100-104.

PMID
25043053
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Rao, RR, Long, JZ, White, JP, Svensson, KJ, Lou, J, Lokurkar, I, Jedrychowski, MP, Ruas, JL, Wrann, CD, Lo, JC, Camera, DM, Lachey, J, Gygi, S, Seehra, J, Hawley, JA, and Spiegelman, BM. "Meteorin-like is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesis." Cell 157, no. 6 (June 2014): 1279-1291.

PMID
24906147
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White, JP, Puppa, MJ, Narsale, A, and Carson, JA. "Characterization of the male ApcMin/+ mouse as a hypogonadism model related to cancer cachexia." Biology Open 2, no. 12 (December 15, 2013): 1346-1353.

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Gomes, AP, Price, NL, Ling, AJY, Moslehi, JJ, Montgomery, MK, Rajman, L, White, JP, Teodoro, JS, Wrann, CD, Hubbard, BP, Mercken, EM, Palmeira, CM, de Cabo, R, Rolo, AP, Turner, N, Bell, EL, and Sinclair, DA. "Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging." Cell 155, no. 7 (December 2013): 1624-1638.

PMID
24360282
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Wrann, CD, White, JP, Salogiannnis, J, Laznik-Bogoslavski, D, Wu, J, Ma, D, Lin, JD, Greenberg, ME, and Spiegelman, BM. "Exercise induces hippocampal BDNF through a PGC-1α/FNDC5 pathway." Cell metabolism 18, no. 5 (November 2013): 649-659.

PMID
24120943
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Pages