Endocrinology, Metabolism, and Nutrition

James R. Bain, PhD

Professor in Medicine
Member of Sarah W. Stedman Nutrition and Metabolism Center
Senior Fellow in the Center for the Study of Aging
Campus mail 300 North Duke Street, Room 48-201, Duke Molecular Physiology Institute, Durham, NC 27701-2047
Phone (919) 479-2320
Email address james.bain@duke.edu

Education and Training

  • Ph.D., University of Washington, 2001

Grants

Publications

Eckhoff, Austin M., Ashton A. Connor, Julie K. M. Thacker, Dan G. Blazer, Harvey G. Moore, Randall P. Scheri, Sandhya A. Lagoo-Deenadayalan, et al. “A Multidimensional Bioinformatic Platform for the Study of Human Response to Surgery.” Ann Surg, March 3, 2022. https://doi.org/10.1097/SLA.0000000000005429.

PMID
35258509
Full Text

Gill, Nathan P., Raji Balasubramanian, James R. Bain, Michael J. Muehlbauer, William L. Lowe, and Denise M. Scholtens. “Path-level interpretation of Gaussian graphical models using the pair-path subscore.” Bmc Bioinformatics 23, no. 1 (January 5, 2022): 12. https://doi.org/10.1186/s12859-021-04542-5.

PMID
34986802
Full Text

Lunyera, Joseph, Clarissa J. Diamantidis, Hayden B. Bosworth, Uptal D. Patel, James Bain, Michael J. Muehlbauer, Olga Ilkayeva, et al. “Urine tricarboxylic acid cycle signatures of early-stage diabetic kidney disease.” Metabolomics 18, no. 1 (December 20, 2021): 5. https://doi.org/10.1007/s11306-021-01858-4.

PMID
34928443
Full Text

Liu, Yu, Alan Kuang, James R. Bain, Michael J. Muehlbauer, Olga R. Ilkayeva, Lynn P. Lowe, Boyd E. Metzger, Christopher B. Newgard, Denise M. Scholtens, and William L. Lowe. “Maternal Metabolites Associated With Gestational Diabetes Mellitus and a Postpartum Disorder of Glucose Metabolism.” J Clin Endocrinol Metab 106, no. 11 (October 21, 2021): 3283–94. https://doi.org/10.1210/clinem/dgab513.

PMID
34255031
Full Text

White, Phillip J., Robert W. McGarrah, Mark A. Herman, James R. Bain, Svati H. Shah, and Christopher B. Newgard. “Insulin action, type 2 diabetes, and branched-chain amino acids: A two-way street.” Mol Metab 52 (October 2021): 101261. https://doi.org/10.1016/j.molmet.2021.101261.

PMID
34044180
Full Text

Truby, Lauren K., Jessica A. Regan, Stephanie N. Giamberardino, Olga Ilkayeva, James Bain, Christopher B. Newgard, Christopher M. O’Connor, et al. “Circulating long chain acylcarnitines and outcomes in diabetic heart failure: an HF-ACTION clinical trial substudy.” Cardiovasc Diabetol 20, no. 1 (August 3, 2021): 161. https://doi.org/10.1186/s12933-021-01353-z.

PMID
34344360
Full Text

Vliet, Stephan van, James R. Bain, Michael J. Muehlbauer, Frederick D. Provenza, Scott L. Kronberg, Carl F. Pieper, and Kim M. Huffman. “A metabolomics comparison of plant-based meat and grass-fed meat indicates large nutritional differences despite comparable Nutrition Facts panels.” Sci Rep 11, no. 1 (July 5, 2021): 13828. https://doi.org/10.1038/s41598-021-93100-3.

PMID
34226581
Full Text

Jachthuber Trub, Catherine, Metin Balikcioglu, Michael Freemark, James Bain, Michael Muehlbauer, Olga Ilkayeva, Phillip J. White, et al. “Impact of lifestyle Intervention on branched-chain amino acid catabolism and insulin sensitivity in adolescents with obesity.” Endocrinol Diabetes Metab 4, no. 3 (July 2021): e00250. https://doi.org/10.1002/edm2.250.

PMID
34277974
Full Text

Tyson, Crystal C., Alison Luciano, Jennifer L. Modliszewski, David L. Corcoran, James R. Bain, Michael Muehlbauer, Olga Ilkayeva, et al. “Effect of Bicarbonate on Net Acid Excretion, Blood Pressure, and Metabolism in Patients With and Without CKD: The Acid Base Compensation in CKD Study.” Am J Kidney Dis 78, no. 1 (July 2021): 38–47. https://doi.org/10.1053/j.ajkd.2020.10.015.

PMID
33810868
Full Text

Pourafshar, Shirin, Mira Nicchitta, Crystal C. Tyson, Laura P. Svetkey, David L. Corcoran, James R. Bain, Michael J. Muehlbauer, et al. “Urine and Plasma Metabolome of Healthy Adults Consuming the DASH (Dietary Approaches to Stop Hypertension) Diet: A Randomized Pilot Feeding Study.” Nutrients 13, no. 6 (May 22, 2021). https://doi.org/10.3390/nu13061768.

PMID
34067295
Full Text

Pages