James R. Bain, PhD

Associate Professor in Medicine
Member of Sarah W. Stedman Nutrition and Metabolism Center
Senior Fellow in the Center for Study of Aging
Campus mail 300 North Duke Street, Room 48-201, Duke Molecular Physiology Institute, Durham, NC 27701-2047
Phone (919) 479-2320
Email address james.bain@duke.edu

Education and Training

  • Ph.D., University of Washington, 2001

Publications

Ravi, S, Parry, TL, Willis, MS, Lockyer, P, Patterson, C, Bain, JR, Stevens, RD, Ilkayeva, OR, Newgard, CB, and Schisler, JC. "Adverse Effects of Fenofibrate in Mice Deficient in the Protein Quality Control Regulator, CHIP." Journal of Cardiovascular Development and Disease 5, no. 3 (August 15, 2018).

PMID
30111698
Full Text

Shantavasinkul, PC, Muehlbauer, MJ, Bain, JR, Ilkayeva, OR, Craig, DM, Newgard, CB, Svetkey, LP, Shah, SH, and Torquati, A. "Improvement in insulin resistance after gastric bypass surgery is correlated with a decline in plasma 2-hydroxybutyric acid." Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery 14, no. 8 (August 2018): 1126-1132.

PMID
29805089
Full Text

Scialla, JJ, Brown, L, Gurley, S, Corcoran, DL, Bain, JR, Muehlbauer, MJ, O'Neal, SK, M O'Connell, T, Wolf, M, Melamed, ML, Hostetter, TH, and Abramowitz, MK. "Metabolic Changes with Base-Loading in CKD." Clinical Journal of the American Society of Nephrology : Cjasn 13, no. 8 (August 2018): 1244-1246.

PMID
29934431
Full Text

Zuo, X, Luciano, A, Pieper, CF, Bain, JR, Kraus, VB, Kraus, WE, Morey, MC, and Cohen, HJ. "Combined Inflammation and Metabolism Biomarker Indices of Robust and Impaired Physical Function in Older Adults." Journal of the American Geriatrics Society 66, no. 7 (July 2018): 1353-1359.

PMID
29738072
Full Text

Bhupathiraju, SN, Guasch-Ferré, M, Gadgil, MD, Newgard, CB, Bain, JR, Muehlbauer, MJ, Ilkayeva, OR, Scholtens, DM, Hu, FB, Kanaya, AM, and Kandula, NR. "Dietary Patterns among Asian Indians Living in the United States Have Distinct Metabolomic Profiles That Are Associated with Cardiometabolic Risk." The Journal of Nutrition 148, no. 7 (July 2018): 1150-1159.

PMID
29893901
Full Text

Parker, D, Sloane, R, Pieper, CF, Hall, KS, Kraus, VB, Kraus, WE, Huebner, JL, Ilkayeva, OR, Bain, JR, Newby, LK, Cohen, HJ, and Morey, MC. "Age-Related Adverse Inflammatory and Metabolic Changes Begin Early in Adulthood." May 22, 2018.

PMID
29985987
Full Text

An, J, Wang, L, Patnode, ML, Ridaura, VK, Haldeman, JM, Stevens, RD, Ilkayeva, O, Bain, JR, Muehlbauer, MJ, Glynn, EL, Thomas, S, Muoio, D, Summers, SA, Vath, JE, Hughes, TE, Gordon, JI, and Newgard, CB. "Physiological mechanisms of sustained fumagillin-induced weight loss." Jci Insight 3, no. 5 (March 8, 2018).

PMID
29515039
Full Text

Parry, TL, Starnes, JW, O'Neal, SK, Bain, JR, Muehlbauer, MJ, Honcoop, A, Ilaiwy, A, Christopher, P, Patterson, C, and Willis, MS. "Untargeted metabolomics analysis of ischemia-reperfusion-injured hearts ex vivo from sedentary and exercise-trained rats." Metabolomics 14, no. 1 (January 2018).

PMID
30104954
Full Text

Abaffy, T, Bain, JR, Muehlbauer, MJ, Spasojevic, I, Lodha, S, Bruguera, E, O'Neal, SK, Kim, SY, and Matsunami, H. "A Testosterone Metabolite 19-Hydroxyandrostenedione Induces Neuroendocrine Trans-Differentiation of Prostate Cancer Cells via an Ectopic Olfactory Receptor." Frontiers in Oncology 8 (January 2018): 162-null.

PMID
29892571
Full Text

Jensen, BC, Parry, TL, Huang, W, Beak, JY, Ilaiwy, A, Bain, JR, Newgard, CB, Muehlbauer, MJ, Patterson, C, Johnson, GL, and Willis, MS. "Effects of the kinase inhibitor sorafenib on heart, muscle, liver and plasma metabolism in vivo using non-targeted metabolomics analysis." British Journal of Pharmacology 174, no. 24 (December 2017): 4797-4811.

PMID
28977680
Full Text

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