Jen-Tsan Ashley Chi, MD, PhD

Associate Professor in Molecular Genetics and Microbiology
Assistant Professor of Medicine
Assistant Professor in Radiation Oncology
Associate Professor of Pharmacology and Cancer Biology
Member of the Duke Cancer Institute
Campus mail 101 Science Dr, Dumc3382, Room 2177A, CIEMAS Bldg, Durham, NC 27708
Phone (919) 668-4759
Email address jentsan.chi@duke.edu

Education and Training

  • Postdoctoral Research, Biochemistry, Stanford University, 2000 - 2004
  • Ph.D., Stanford University, 2000
  • M.D., National Taiwan University, 1991

Publications

Walzer, KA, Kubicki, DM, Tang, X, and Chi, J-TA. "Single-Cell Analysis Reveals Distinct Gene Expression and Heterogeneity in Male and Female Plasmodium falciparum Gametocytes." Msphere 3, no. 2 (April 11, 2018).

PMID
29643077
Full Text

Lin, C-C, Kitagawa, M, Tang, X, Hou, M-H, Wu, J, Qu, DC, Srinivas, V, Liu, X, Thompson, JW, Mathey-Prevot, B, Yao, T-P, Lee, SH, and Chi, J-T. "CoA synthase regulates mitotic fidelity via CBP-mediated acetylation." March 12, 2018.

PMID
29531224
Full Text

Justus, CR, Sanderlin, EJ, Dong, L, Sun, T, Chi, J-T, Lertpiriyapong, K, and Yang, LV. "Contextual tumor suppressor function of T cell death-associated gene 8 (TDAG8) in hematological malignancies." Journal of Translational Medicine 15, no. 1 (October 10, 2017): 204-null.

PMID
29017562
Full Text

Lee, C-T, Zhou, Y, Roy-Choudhury, K, Siamakpour-Reihani, S, Young, K, Hoang, P, Kirkpatrick, JP, Chi, J-TA, Dewhirst, MW, and Horton, JK. "Subtype-Specific Radiation Response and Therapeutic Effect of FAS Death Receptor Modulation in Human Breast Cancer." Radiation Research 188, no. 2 (August 2017): 169-180.

PMID
28598289
Full Text

Chen, P-H, Smith, TJ, Wu, J, Siesser, PF, Bisnett, BJ, Khan, F, Hogue, M, Soderblom, E, Tang, F, Marks, JR, Major, MB, Swarts, BM, Boyce, M, and Chi, J-T. "Glycosylation of KEAP1 links nutrient sensing to redox stress signaling." The Embo Journal 36, no. 15 (August 2017): 2233-2250.

PMID
28663241
Full Text

Tang, X, Ding, C-K, Wu, J, Sjol, J, Wardell, S, Spasojevic, I, George, D, McDonnell, DP, Hsu, DS, Chang, JT, and Chi, J-T. "Cystine addiction of triple-negative breast cancer associated with EMT augmented death signaling." Oncogene 36, no. 30 (July 2017): 4235-4242.

PMID
27869167
Full Text

Alfaqih, MA, Nelson, ER, Liu, W, Safi, R, Jasper, JS, Macias, E, Geradts, J, Thompson, JW, Dubois, LG, Freeman, MR, Chang, C-Y, Chi, J-T, McDonnell, DP, and Freedland, SJ. "CYP27A1 Loss Dysregulates Cholesterol Homeostasis in Prostate Cancer." Cancer Research 77, no. 7 (April 2017): 1662-1673.

PMID
28130224
Full Text

Walzer, KA, and Chi, J-T. "Trans-kingdom small RNA transfer during host-pathogen interactions: The case of P. falciparum and erythrocytes." Rna Biology 14, no. 4 (April 2017): 442-449. (Review)

PMID
28277932
Full Text

Siska, PJ, Kim, B, Ji, X, Hoeksema, MD, Massion, PP, Beckermann, KE, Wu, J, Chi, J-T, Hong, J, and Rathmell, JC. "Fluorescence-based measurement of cystine uptake through xCT shows requirement for ROS detoxification in activated lymphocytes." Journal of Immunological Methods 438 (November 2016): 51-58.

PMID
27594594
Full Text

Geer Wallace, MA, Kwon, D-Y, Weitzel, DH, Lee, C-T, Stephenson, TN, Chi, J-T, Mook, RA, Dewhirst, MW, Hong, J, and Fitzgerald, MC. "Discovery of Manassantin A Protein Targets Using Large-Scale Protein Folding and Stability Measurements." Journal of Proteome Research 15, no. 8 (August 2016): 2688-2696.

PMID
27322910
Full Text

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