Education and Training
- Ph.D., University of Basel, 2003
- M.S., University of Wisconsin at Madison, 1998
Ponzio, V, Chen, Y, Rodrigues, AM, Tenor, JL, Toffaletti, DL, Medina-Pestana, JO, Colombo, AL, and Perfect, JR. "Genotypic diversity and clinical outcome of cryptococcosis in renal transplant recipients in Brazil." Emerging Microbes & Infections 8, no. 1 (January 2019): 119-129.
Shaw, KJ, Schell, WA, Covel, J, Duboc, G, Giamberardino, C, Kapoor, M, Moloney, M, Soltow, QA, Tenor, JL, Toffaletti, DL, Trzoss, M, Webb, P, and Perfect, JR. "In Vitro and In Vivo Evaluation of APX001A/APX001 and Other Gwt1 Inhibitors against Cryptococcus." Antimicrobial Agents and Chemotherapy 62, no. 8 (August 2018).
Miao, Y, Tenor, JL, Toffaletti, DL, Maskarinec, SA, Liu, J, Lee, RE, Perfect, JR, and Brennan, RG. "Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for Novel Antifungal Drug Design." Mbio 8, no. 4 (July 25, 2017).
Desjardins, CA, Giamberardino, C, Sykes, SM, Yu, C-H, Tenor, JL, Chen, Y, Yang, T, Jones, AM, Sun, S, Haverkamp, MR, Heitman, J, Litvintseva, AP, Perfect, JR, and Cuomo, CA. "Population genomics and the evolution of virulence in the fungal pathogen Cryptococcus neoformans." Genome Research 27, no. 7 (July 2017): 1207-1219.
Chen, Y, Farrer, RA, Giamberardino, C, Sakthikumar, S, Jones, A, Yang, T, Tenor, JL, Wagih, O, Van Wyk, M, Govender, NP, Mitchell, TG, Litvintseva, AP, Cuomo, CA, and Perfect, JR. "Microevolution of Serial Clinical Isolates of Cryptococcus neoformans var. grubii and C. gattii." Mbio 8, no. 2 (March 7, 2017).
Perfect, JR, Tenor, JL, Miao, Y, and Brennan, RG. "Trehalose pathway as an antifungal target." Virulence 8, no. 2 (February 2017): 143-149. (Review)
Tenor, JL, Oehlers, SH, Yang, JL, Tobin, DM, and Perfect, JR. "Live Imaging of Host-Parasite Interactions in a Zebrafish Infection Model Reveals Cryptococcal Determinants of Virulence and Central Nervous System Invasion." Mbio 6, no. 5 (September 29, 2015): e01425-e01415.
Chen, Y, Toffaletti, DL, Tenor, JL, Litvintseva, AP, Fang, C, Mitchell, TG, McDonald, TR, Nielsen, K, Boulware, DR, Bicanic, T, and Perfect, JR. "The Cryptococcus neoformans transcriptome at the site of human meningitis." Mbio 5, no. 1 (February 4, 2014).
Frazzitta, AE, Vora, H, Price, MS, Tenor, JL, Betancourt-Quiroz, M, Toffaletti, DL, Cheng, N, and Perfect, JR. "Nitrogen source-dependent capsule induction in human-pathogenic cryptococcus species." Eukaryotic Cell 12, no. 11 (November 2013): 1439-1450.
Fang, W, Price, MS, Toffaletti, DL, Tenor, J, Betancourt-Quiroz, M, Price, JL, Pan, W-H, Liao, W-Q, and Perfect, JR. "Pleiotropic effects of deubiquitinating enzyme Ubp5 on growth and pathogenesis of Cryptococcus neoformans." PLoS One 7, no. 6 (2012): e38326-.