Joe Brice Weinberg, MD

Professor of Medicine
Associate Professor of Obstetrics and Gynecology
Professor of Immunology
Affiliate, Duke Global Health Institute
Member of the Duke Cancer Institute
Campus mail Duke Box 3396, Durham, NC 27708
Phone (919) 286-6833
Email address weinb001@duke.edu

Dr. Weinberg is a board-certified hematologist and medical oncologist who serves as Professor of Medicine and Immunology and Associate Professor of Obstetrics and Gynecology at the Duke University Medical Center, and staff physician in hematology-oncology at the Durham V.A. Medical Center. His clinical interests are in hematology and oncology, and his research focuses on blood cells, nitric oxide (NO), and leukemia. The work includes studies of resistance to infection, pathways of inflammation, and regulation of normal and leukemic cell life and death. His current work includes studies of leukemia (primarily chronic lymphocytic leukemia); the roles of NO and arginine in the resistance to malaria; and the interactions of NO, prostaglandins, and mechanical force in inflammation and arthritis.

Education and Training

  • Fellowship, Hematology Oncology, University of Utah School of Medicine, 1973 - 1976
  • Internship & Residency, University of Arkansas at Little Rock, 1969 - 1971
  • M.D., University of Arkansas at Little Rock, 1969
  • B.S., University of Arkansas, Fayetteville, 1966

Publications

Goldberg, J. S., and J. B. Weinberg. “USE OF POLYMER D-LACTIC ACID (PDLA) OR EQUIVALENTS THEREOF TO INHIBIT GROWTH OF CANCER CELLS AND DIAGNOSE CANCER.” USPTO, December 30, 2019.

Scholars@Duke

Rubach, Matthew P., Haoyue Zhang, Salvatore M. Florence, Jackson P. Mukemba, Ayam R. Kalingonji, Nicholas M. Anstey, Tsin W. Yeo, et al. “Kinetic and Cross-Sectional Studies on the Genesis of Hypoargininemia in Severe Pediatric Plasmodium falciparum Malaria..” Infect Immun 87, no. 4 (April 2019). https://doi.org/10.1128/IAI.00655-18.

PMID
30718287
Full Text

Yeo, T. W., J. B. Weinberg, D. A. Lampah, E. Kenangalem, P. Bush, Y. Chen, R. N. Price, et al. “Glycocalyx Breakdown is Associated with Severe Disease and Fatal Outcome in Plasmodium falciparum Malaria..” Clin Infect Dis, February 12, 2019. https://doi.org/10.1093/cid/ciz038.

PMID
30753363
Full Text

Brander, Danielle M., Daphne R. Friedman, Alicia D. Volkheimer, Dale J. Christensen, Laura Z. Rassenti, Thomas J. Kipps, Eross Guadalupe, et al. “SET alpha and SET beta mRNA isoforms in chronic lymphocytic leukaemia..” British Journal of Haematology 184, no. 4 (February 2019): 605–15. https://doi.org/10.1111/bjh.15677.

PMID
30443898
Full Text

Friedman, Daphne R., Eross Guadalupe, Alicia Volkheimer, Joseph O. Moore, and J Brice Weinberg. “Clinical outcomes in chronic lymphocytic leukaemia associated with expression of CD5, a negative regulator of B-cell receptor signalling..” Br J Haematol 183, no. 5 (December 2018): 747–54. https://doi.org/10.1111/bjh.15632.

PMID
30407619
Full Text

Kleinstern, Geffen, Nicola J. Camp, Lynn R. Goldin, Celine M. Vachon, Claire M. Vajdic, Silvia de Sanjose, J Brice Weinberg, et al. “Association of polygenic risk score with the risk of chronic lymphocytic leukemia and monoclonal B-cell lymphocytosis..” Blood 131, no. 23 (June 7, 2018): 2541–51. https://doi.org/10.1182/blood-2017-11-814608.

PMID
29674426
Full Text

Goldberg, J. S., and Joe Brice Weinberg. “LOCAL APPLICATION OF D-LACTIC ACID DIMER IS SELECTIVELY CYTOTOXIC WHEN APPLIED TO CANCER CELLS.” USPTO, March 29, 2018.

Scholars@Duke

Brander, Danielle, J Brice Weinberg, Daphne Friedman, Tiffany Stewart, and David Rizzieri. “Phase I trial of lenalidomide in combination with plerixafor for relapsed/refractory chronic lymphocytic leukemia (CLL): follow-up and correlative analysis.” In Leukemia & Lymphoma, 58:35–37. TAYLOR & FRANCIS LTD, 2017.

Scholars@Duke

Brander, Danielle, J Brice Weinberg, Daphne Friedman, Tiffany Stewart, and David Rizzieri. “Phase I trial of lenalidomide in combination with plerixafor for relapsed/refractory chronic lymphocytic leukemia (CLL): follow-up and correlative analysis.” In Leukemia & Lymphoma, 58:35–37. TAYLOR & FRANCIS LTD, 2017.

Scholars@Duke

Rubach, Matthew P., Jackson Mukemba, Salvatore Florence, Nicholas M. Anstey, Tsin W. Yeo, Esther D. Mwaikambo, J Brice Weinberg, and Donald L. Granger. “SEVERE DEFICIENCIES OF AMINO ACID PRECURSORS FOR L-ARGININE DE NOVO BIOSYNTHESIS IN PEDIATRIC FALCIPARUM MALARIA: IMPLICATIONS FOR NITRIC OXIDE INSUFFICIENCY.” In American Journal of Tropical Medicine and Hygiene, 97:478–478. AMER SOC TROP MED & HYGIENE, 2017.

Scholars@Duke

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