Joe Brice Weinberg, MD

Professor of Medicine
Associate Professor of Obstetrics and Gynecology
Professor of Immunology
Affiliate, Duke Global Health Institute
Member of the Duke Cancer Institute
Campus mail Duke Box 3396, Durham, NC 27708
Phone (919) 286-6833
Email address weinb001@duke.edu

Dr. Weinberg is a board-certified hematologist and medical oncologist who serves as Professor of Medicine and Immunology and Associate Professor of Obstetrics and Gynecology at the Duke University Medical Center, and staff physician in hematology-oncology at the Durham V.A. Medical Center. His clinical interests are in hematology and oncology, and his research focuses on blood cells, nitric oxide (NO), and leukemia. The work includes studies of resistance to infection, pathways of inflammation, and regulation of normal and leukemic cell life and death. His current work includes studies of leukemia (primarily chronic lymphocytic leukemia); the roles of NO and arginine in the resistance to malaria; and the interactions of NO, prostaglandins, and mechanical force in inflammation and arthritis.

Education and Training

  • Fellowship, Hematology Oncology, University of Utah School of Medicine, 1973 - 1976
  • Internship & Residency, University of Arkansas at Little Rock, 1969 - 1971
  • M.D., University of Arkansas at Little Rock, 1969
  • B.S., University of Arkansas, Fayetteville, 1966

Publications

Rubach, Matthew P., Jackson Mukemba, Salvatore Florence, Nicholas M. Anstey, Tsin W. Yeo, Esther D. Mwaikambo, J Brice Weinberg, and Donald L. Granger. “SEVERE DEFICIENCIES OF AMINO ACID PRECURSORS FOR L-ARGININE DE NOVO BIOSYNTHESIS IN PEDIATRIC FALCIPARUM MALARIA: IMPLICATIONS FOR NITRIC OXIDE INSUFFICIENCY.” In American Journal of Tropical Medicine and Hygiene, 97:478–478. AMER SOC TROP MED & HYGIENE, 2017.

Scholars@Duke

Winkler, Mark T., Ryan T. Bushey, Elizabeth B. Gottlin, Michael J. Campa, Eross S. Guadalupe, Alicia D. Volkheimer, J Brice Weinberg, and Edward F. Patz. “Enhanced CDC of B cell chronic lymphocytic leukemia cells mediated by rituximab combined with a novel anti-complement factor H antibody..” Plos One 12, no. 6 (2017). https://doi.org/10.1371/journal.pone.0179841.

PMID
28658265
Full Text

Yeo, Tsin W., Salvatore M. Florence, Ayam R. Kalingonji, Youwei Chen, Donald L. Granger, Nicholas M. Anstey, Esther D. Mwaikambo, and J Brice Weinberg. “Decreased Microvascular Function in Tanzanian Children With Severe and Uncomplicated Falciparum Malaria..” Open Forum Infect Dis 4, no. 2 (2017). https://doi.org/10.1093/ofid/ofx079.

PMID
28852670
Full Text

Lee, Seung, Coby Palmares, Niko Koutsoukos, J Brice Weinberg, Trisa Palmares, Alice Song, Harold Song, et al. “Ruxolitinib Used to Treat Hypereosinophilic Syndrome.” In Blood, Vol. 128. AMER SOC HEMATOLOGY, 2016.

Scholars@Duke

Davis, Carter Thomas, Arati V. Rao, Eross Guadalupe, Dale J. Christensen, and J Brice Weinberg. “Fingolimod Is Cytotoxic in Acute Myeloid Leukemia Independent of Additional Chemotherapeutic Agents.” In Blood, Vol. 128. AMER SOC HEMATOLOGY, 2016.

Scholars@Duke

Friedman, Daphne R., Eross Guadeloupe, Alicia Volkheimer, and J Brice Weinberg. “Surface CD5 Protein Risk Stratifies Chronic Lymphocytic Leukemia.” In Blood, Vol. 128. AMER SOC HEMATOLOGY, 2016.

Scholars@Duke

Barber, Bridget E., Timothy William, Matthew J. Grigg, Kim A. Piera, Youwei Chen, Hao Wang, J Brice Weinberg, Tsin W. Yeo, and Nicholas M. Anstey. “Nitric Oxide-Dependent Endothelial Dysfunction and Reduced Arginine Bioavailability in Plasmodium vivax Malaria but No Greater Increase in Intravascular Hemolysis in Severe Disease..” J Infect Dis 214, no. 10 (November 15, 2016): 1557–64. https://doi.org/10.1093/infdis/jiw427.

PMID
27630198
Full Text

Siska, Peter J., Gerritje J. W. van der Windt, Rigel J. Kishton, Sivan Cohen, William Eisner, Nancie J. MacIver, Arnon P. Kater, J Brice Weinberg, and Jeffrey C. Rathmell. “Suppression of Glut1 and Glucose Metabolism by Decreased Akt/mTORC1 Signaling Drives T Cell Impairment in B Cell Leukemia..” J Immunol 197, no. 6 (September 15, 2016): 2532–40. https://doi.org/10.4049/jimmunol.1502464.

PMID
27511728
Full Text

Weinberg, J Brice, Alicia D. Volkheimer, Matthew P. Rubach, Salvatore M. Florence, Jackson P. Mukemba, Ayam R. Kalingonji, Charles Langelier, et al. “Monocyte polarization in children with falciparum malaria: relationship to nitric oxide insufficiency and disease severity..” Sci Rep 6 (July 7, 2016). https://doi.org/10.1038/srep29151.

PMID
27385484
Full Text

Goldberg, J. S., and J. B. Weinberg. “USE OF POLYMER D-LACTIC ACID (PDLA) OR EQUIVALENTS THEREOF TO INHIBIT GROWTH OF CANCER CELLS AND DIAGNOSE CANCER.” USPTO, July 5, 2016.

Scholars@Duke

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