Joe Brice Weinberg, MD

Professor of Medicine
Associate Professor of Obstetrics and Gynecology
Professor of Immunology
Affiliate, Duke Global Health Institute
Member of the Duke Cancer Institute
Campus mail Duke Box 3396, Durham, NC 27708
Phone (919) 286-6833
Email address weinb001@duke.edu

Dr. Weinberg is a board-certified hematologist and medical oncologist who serves as Professor of Medicine and Immunology and Associate Professor of Obstetrics and Gynecology at the Duke University Medical Center, and staff physician in hematology-oncology at the Durham V.A. Medical Center. His clinical interests are in hematology and oncology, and his research focuses on blood cells, nitric oxide (NO), and leukemia. The work includes studies of resistance to infection, pathways of inflammation, and regulation of normal and leukemic cell life and death. His current work includes studies of leukemia (primarily chronic lymphocytic leukemia); the roles of NO and arginine in the resistance to malaria; and the interactions of NO, prostaglandins, and mechanical force in inflammation and arthritis.

Education and Training

  • Fellowship, Hematology Oncology, University of Utah School of Medicine, 1973 - 1976
  • Internship & Residency, University of Arkansas at Little Rock, 1969 - 1971
  • M.D., University of Arkansas at Little Rock, 1969
  • B.S., University of Arkansas, Fayetteville, 1966

Publications

Rubach, MP, Mukemba, J, Florence, S, Anstey, NM, Yeo, TW, Mwaikambo, ED, Weinberg, JB, and Granger, DL. "SEVERE DEFICIENCIES OF AMINO ACID PRECURSORS FOR L-ARGININE DE NOVO BIOSYNTHESIS IN PEDIATRIC FALCIPARUM MALARIA: IMPLICATIONS FOR NITRIC OXIDE INSUFFICIENCY." 66th Annual Meeting of the American-Society-of-Tropical-Medicine-and-Hygiene (ASTMH). Baltimore, MD. November 5, 2017 - November 9, 2017.: AMER SOC TROP MED & HYGIENE, January 1, 2017.

Scholars@Duke

Lee, S, Palmares, C, Koutsoukos, N, Weinberg, JB, Palmares, T, Song, A, Song, H, Benedicto, S, Song, M, Vu, P, and Song, J. "Ruxolitinib Used to Treat Hypereosinophilic Syndrome." 58th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH). San Diego, CA. December 3, 2016 - December 6, 2016.: AMER SOC HEMATOLOGY, December 2, 2016.

Scholars@Duke

Davis, CT, Rao, AV, Guadalupe, E, Christensen, DJ, and Weinberg, JB. "Fingolimod Is Cytotoxic in Acute Myeloid Leukemia Independent of Additional Chemotherapeutic Agents." 58th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH). San Diego, CA. December 3, 2016 - December 6, 2016.: AMER SOC HEMATOLOGY, December 2, 2016.

Scholars@Duke

Friedman, DR, Guadeloupe, E, Volkheimer, A, and Weinberg, JB. "Surface CD5 Protein Risk Stratifies Chronic Lymphocytic Leukemia." 58th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH). San Diego, CA. December 3, 2016 - December 6, 2016.: AMER SOC HEMATOLOGY, December 2, 2016.

Scholars@Duke

Barber, BE, William, T, Grigg, MJ, Piera, KA, Chen, Y, Wang, H, Weinberg, JB, Yeo, TW, and Anstey, NM. "Nitric Oxide-Dependent Endothelial Dysfunction and Reduced Arginine Bioavailability in Plasmodium vivax Malaria but No Greater Increase in Intravascular Hemolysis in Severe Disease." The Journal of Infectious Diseases 214, no. 10 (November 2016): 1557-1564.

PMID
27630198
Full Text

Siska, PJ, van der Windt, GJW, Kishton, RJ, Cohen, S, Eisner, W, MacIver, NJ, Kater, AP, Weinberg, JB, and Rathmell, JC. "Suppression of Glut1 and Glucose Metabolism by Decreased Akt/mTORC1 Signaling Drives T Cell Impairment in B Cell Leukemia." Journal of Immunology (Baltimore, Md. : 1950) 197, no. 6 (September 2016): 2532-2540.

PMID
27511728
Full Text

Weinberg, JB, Volkheimer, AD, Rubach, MP, Florence, SM, Mukemba, JP, Kalingonji, AR, Langelier, C, Chen, Y, Bush, M, Yeo, TW, Granger, DL, Anstey, NM, and Mwaikambo, ED. "Monocyte polarization in children with falciparum malaria: relationship to nitric oxide insufficiency and disease severity." Scientific Reports 6 (July 7, 2016): 29151-null.

PMID
27385484
Full Text

Goldberg, JS, and Weinberg, JB. "USE OF POLYMER D-LACTIC ACID (PDLA) OR EQUIVALENTS THEREOF TO INHIBIT GROWTH OF CANCER CELLS AND DIAGNOSE CANCER." (July 5, 2016). (Digital Edition)

Scholars@Duke

Friedman, DR, Sibley, AB, Owzar, K, Chaffee, KG, Slager, S, Kay, NE, Hanson, CA, Ding, W, Shanafelt, TD, Weinberg, JB, and Wilcox, RA. "Relationship of blood monocytes with chronic lymphocytic leukemia aggressiveness and outcomes: a multi-institutional study." American Journal of Hematology 91, no. 7 (July 2016): 687-691.

PMID
27037726
Full Text

Heyman, B, Volkheimer, AD, and Weinberg, JB. "Double IGHV DNA gene rearrangements in CLL: influence of mixed-mutated and -unmutated rearrangements on outcomes in CLL." Blood Cancer Journal 6, no. 7 (July 2016): e440-null. (Letter)

PMID
27367477
Full Text

Pages