Jon Paul Gockerman, MD

Professor Emeritus of Medicine
Campus mail 25154 Morris Bldg, Durham, NC 27710
Phone (919) 684-8964
Email address gocke002@mc.duke.edu

My research effort is involved in clinical research studies through the CALGB as well as several sub interests. My interest is the use of 131I MIBG in the treatment of carcinoids. We have completed a dose seeking study to determine the maximum tolerated dose. This has been completed and this paper is in preparation for publication. We plan to do an additional study of randomization in patients with this agent to see if we can determine an objective response rate in a controlled group of patients.

The secondary issue is that of high dose chemotherapy in lymphoma. We have completed a study involving use of high dose chemotherapy in a transplant setting in patients with refractory lymphoma. This study has treated over 100 patients and is in the process of being written up.

Education and Training

  • M.D., The University of Chicago, 1967

Publications

Zelenetz, Andrew D., Ranjana H. Advani, Francis Buadi, Fernando Cabanillas, Michael A. Caligiuri, Myron S. Czuczman, Lloyd E. Damon, et al. “Non-Hodgkin's lymphoma. Clinical practice guidelines in oncology.” J Natl Compr Canc Netw 4, no. 3 (March 2006): 258–310. https://doi.org/10.6004/jnccn.2006.0025.

PMID
16507273
Full Text

Koontz, Bridget F., John P. Kirkpatrick, Robert W. Clough, Robert G. Prosnitz, Jon P. Gockerman, Joseph O. Moore, and Leonard R. Prosnitz. “Combined-modality therapy versus radiotherapy alone for treatment of early-stage Hodgkin's disease: cure balanced against complications.” J Clin Oncol 24, no. 4 (February 1, 2006): 605–11. https://doi.org/10.1200/JCO.2005.02.9850.

PMID
16446333
Full Text

Levesque, Marc C., Youwei Chen, Bethany E. Beasley, Charles W. O’Loughlin, Jon P. Gockerman, Joseph O. Moore, and J Brice Weinberg. “Chronic lymphocytic leukemia cell CD38 expression and inducible nitric oxide synthase expression are associated with serum IL-4 levels.” Leuk Res 30, no. 1 (January 2006): 24–28. https://doi.org/10.1016/j.leukres.2005.05.022.

PMID
16039714
Full Text

Simsir, Sinan A., Shu S. Lin, Laura J. Blue, John P. Gockerman, Stuart D. Russell, and Carmelo A. Milano. “Left ventricular assist device as destination therapy in doxorubicin-induced cardiomyopathy.” Ann Thorac Surg 80, no. 2 (August 2005): 717–19. https://doi.org/10.1016/j.athoracsur.2004.02.036.

PMID
16039240
Full Text

Neelapu, Sattva S., Barry L. Gause, Daniel A. Nikcevich, Stephen J. Schuster, Jane Winter, Jon P. Gockerman, Thomas Loughran, et al. “Phase III randomized trial of patient-specific vaccination for previously untreated patients with follicular lymphoma in first complete remission: protocol summary and interim report.” Clin Lymphoma 6, no. 1 (June 2005): 61–64. https://doi.org/10.3816/clm.2005.n.031.

PMID
15989711
Full Text

Ettinger, David S., Juan P. Arnoletti, Jon P. Gockerman, Charles Handorf, Kathleen Anne Havlin, Charlotte D. Jacobs, Milind Javle, et al. “Occult primary cancer clinical practice guidelines.” J Natl Compr Canc Netw 3, no. 2 (March 2005): 214–33.

PMID
19817031
Scholars@Duke

Safford, Shawn D., R Edward Coleman, Jon P. Gockerman, Joseph Moore, Jerome Feldman, Mark W. Onaitis, Douglas S. Tyler, and John A. Olson. “Iodine-131 metaiodobenzylguanidine treatment for metastatic carcinoid. Results in 98 patients.” Cancer 101, no. 9 (November 1, 2004): 1987–93. https://doi.org/10.1002/cncr.20592.

PMID
15455358
Full Text

Talbot, Jeffrey, Valerie K. Ibom, David A. Rizzieri, Robert Barrier, Donna Niedzwieki, Carlos M. DeCastro, Joseph O. Moore, et al. “Dose-intense cyclophosphamide and etoposide for patients with refractory or high-risk non-Hodgkin's lymphoma.” Clin Lymphoma 5, no. 2 (September 2004): 116–22. https://doi.org/10.3816/clm.2004.n.018.

PMID
15453927
Full Text

Rizzieri, David A., Gamal Akabani, Michael R. Zalutsky, R Edward Coleman, Scott D. Metzler, James E. Bowsher, Bonnie Toaso, et al. “Phase 1 trial study of 131I-labeled chimeric 81C6 monoclonal antibody for the treatment of patients with non-Hodgkin lymphoma.” Blood 104, no. 3 (August 1, 2004): 642–48. https://doi.org/10.1182/blood-2003-12-4264.

PMID
15100153
Full Text

Pages