Endocrinology, Metabolism, and Nutrition

Jonathan Edward Campbell, PhD

Associate Professor in Medicine
Assistant Research Professor in Pharmacology & Cancer Biology
Associate Research Professor in Pharmacology & Cancer Biology
Member of Duke Molecular Physiology Institute
Email address jonathan.campbell@duke.edu

Education and Training

  • Ph.D., York University in Toronto (Canada), 2010

Grants

Publications

El, K., S. M. Gray, M. E. Capozzi, E. R. Knuth, E. Jin, B. Svendsen, A. Clifford, et al. “GIP mediates the incretin effect and glucose tolerance by dual actions on α cells and β cells.” Sci Adv 7, no. 11 (March 2021). https://doi.org/10.1126/sciadv.abf1948.

PMID
33712466
Full Text

Huynh, Frank K., Brett S. Peterson, Kristin A. Anderson, Zhihong Lin, Aeowynn J. Coakley, Fiara M. S. Llaguno, Thi-Tina N. Nguyen, et al. “β-Cell-specific ablation of sirtuin 4 does not affect nutrient-stimulated insulin secretion in mice.” Am J Physiol Endocrinol Metab 319, no. 4 (October 1, 2020): E805–13. https://doi.org/10.1152/ajpendo.00170.2020.

PMID
32865009
Full Text

Willard, Francis S., Jonathan D. Douros, Maria Bn Gabe, Aaron D. Showalter, David B. Wainscott, Todd M. Suter, Megan E. Capozzi, et al. “Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist.” Jci Insight 5, no. 17 (September 3, 2020). https://doi.org/10.1172/jci.insight.140532.

PMID
32730231
Full Text

Gray, Sarah M., Yurong Xin, Elizabeth C. Ross, Bryanna M. Chazotte, Megan E. Capozzi, Kimberley El, Berit Svendsen, et al. “Discordance between GLP-1R gene and protein expression in mouse pancreatic islet cells.” J Biol Chem 295, no. 33 (August 14, 2020): 11529–41. https://doi.org/10.1074/jbc.RA120.014368.

PMID
32554468
Full Text

Gilroy, C. A., M. E. Capozzi, A. K. Varanko, J. Tong, D. A. D’Alessio, J. E. Campbell, and A. Chilkoti. “Sustained release of a GLP-1 and FGF21 dual agonist from an injectable depot protects mice from obesity and hyperglycemia.” Sci Adv 6, no. 35 (August 2020): eaaz9890. https://doi.org/10.1126/sciadv.aaz9890.

PMID
32923621
Full Text

Al Batran, Rami, Keshav Gopal, Megan E. Capozzi, Jadin J. Chahade, Bruno Saleme, S Amirhossein Tabatabaei-Dakhili, Amanda A. Greenwell, et al. “Pimozide Alleviates Hyperglycemia in Diet-Induced Obesity by Inhibiting Skeletal Muscle Ketone Oxidation.” Cell Metab 31, no. 5 (May 5, 2020): 909-919.e8. https://doi.org/10.1016/j.cmet.2020.03.017.

PMID
32275862
Full Text

Eshreif, Amina, Rami Al Batran, K Lockhart Jamieson, Ahmed M. Darwesh, Keshav Gopal, Amanda A. Greenwell, Igor Zlobine, et al. “l-Citrulline supplementation improves glucose and exercise tolerance in obese male mice.” Exp Physiol 105, no. 2 (February 2020): 270–81. https://doi.org/10.1113/EP088109.

PMID
31802553
Full Text

Pages