Jonathan Paul Piccini, MD

Associate Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail Dept of Medicine, Durham, NC 27710
Phone (919) 684-8111
Email address jonathan.piccini@duke.edu

Jonathan P. Piccini, MD, MHS is a clinical cardiac electrophysiologist and Associate Professor of Medicine at Duke University Medical Center and the Duke Clinical Research Institute. His research interests include the conduct of clinical trials and the assessment of cardiovascular therapeutics for the care of patients with heart rhythm disorders. At present, he is the Director of the EP Clinical Trials Program and Arrhythmia Core Laboratory at Duke University. He also serves on the Clinical Working Group of the American Heart Association’s Get With The Guidelines – Atrial fibrillation (GWTG-Afib) registry program. He is an associate editor for the American Heart Journal and serves on the editorial board of Heart Rhythm, the European Heart Journal, and the Journal of Cardiac Electrophysiology. He is the Principal Investigator of the data and coordinating center for ORBIT AF, a 25,000 patient registry focused on quality of care and improving outcomes in patients with atrial fibrillation. He is also the PI of the GENETIC AF clinical trial, the first clinical trial to study genotype-directed rhythm control therapy for atrial fibrillation. He also serves on the steering committees of multiple international randomized trials focused on the treatment of atrial fibrillation.  Dr. Piccini has more than 175 publications in the field of heart rhythm medicine. Clinically, his focus is on the care of patients with atrial fibrillation and complex arrhythmias, with particular emphasis on catheter ablation and lead extraction.

Education and Training

  • Clinical Cardiac Electrophysiology Fellowship, Medicine, Duke University School of Medicine, 2009 - 2011
  • Cardiology Fellowship, Medicine, Duke University School of Medicine, 2005 - 2009
  • Internal Medicine Residency, Medicine, Johns Hopkins University School of Medicine, 2002 - 2005
  • M.H.S., Duke University, 2009
  • M.D., Northwestern University Feinberg School of Medicine, 2002

Publications

Steinberg, BA, Gao, H, Shrader, P, Pieper, K, Thomas, L, Camm, AJ, Ezekowitz, MD, Fonarow, GC, Gersh, BJ, Goldhaber, S, Haas, S, Hacke, W, Kowey, PR, Ansell, J, Mahaffey, KW, Naccarelli, G, Reiffel, JA, Turpie, A, Verheugt, F, Piccini, JP, Kakkar, A, Peterson, ED, and Fox, KAA. "International trends in clinical characteristics and oral anticoagulation treatment for patients with atrial fibrillation: Results from the GARFIELD-AF, ORBIT-AF I, and ORBIT-AF II registries (Accepted)." American Heart Journal 194 (December 2017): 132-140.

Full Text

Parikh, KS, and Piccini, JP. "Pharmacogenomics of Bucindolol in Atrial Fibrillation and Heart Failure. (Accepted)" Current heart failure reports 14, no. 6 (December 2017): 529-535. (Review)

PMID
28975475
Full Text

Chen, ST, Hellkamp, AS, Becker, RC, Berkowitz, SD, Breithardt, G, Fox, KAA, Hacke, W, Halperin, JL, Hankey, GJ, Mahaffey, KW, Nessel, CC, Piccini, JP, Singer, DE, and Patel, MR. "Outcome of Patients Receiving Thrombolytic Therapy While on Rivaroxaban for Nonvalvular Atrial Fibrillation (from Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation)." The American journal of cardiology 120, no. 10 (November 2017): 1837-1840.

PMID
28886856
Full Text

Pokorney, SD, Mi, X, Lewis, RK, Greiner, M, Epstein, LM, Carrillo, RG, Zeitler, EP, Al-Khatib, SM, Hegland, DD, and Piccini, JP. "Outcomes Associated With Extraction Versus Capping and Abandoning Pacing and Defibrillator Leads." Circulation 136, no. 15 (October 2017): 1387-1395.

PMID
28830879
Full Text

Piccini, JP, Sanders, P, Shah, R, Roberts, G, Karst, E, and Turakhia, MP. "Impact of Tachyarrhythmia Detection Rate and Time from Detection to Shock on Outcomes in Nationwide US Practice." The American journal of cardiology 120, no. 8 (October 2017): 1325-1331.

PMID
28947249
Full Text

Piccini, JP, and Jones, WS. "Triple Therapy for Atrial Fibrillation after PCI." The New England journal of medicine 377, no. 16 (October 2017): 1580-1582.

PMID
29045197
Full Text

Black-Maier, E, and Piccini, JP. "Reply to the Editor- Contact Force-Sensing Catheters and Increased Risk of Atrioesophageal Fistula: Is the Tool to Blame or the Workmen?." Heart rhythm (September 13, 2017). (Letter)

PMID
28917565
Full Text

Black-Maier, E, Pokorney, SD, Barnett, AS, Zeitler, EP, Sun, AY, Jackson, KP, Bahnson, TD, Daubert, JP, and Piccini, JP. "Risk of atrioesophageal fistula formation with contact force-sensing catheters." Heart rhythm 14, no. 9 (September 2017): 1328-1333.

PMID
28416466
Full Text

Black-Maier, E, Kim, S, Steinberg, BA, Fonarow, GC, Freeman, JV, Kowey, PR, Ansell, J, Gersh, BJ, Mahaffey, KW, Naccarelli, G, Hylek, EM, Go, AS, Peterson, ED, Piccini, JP, and Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) Investigators, . "Oral anticoagulation management in patients with atrial fibrillation undergoing cardiac implantable electronic device implantation." Clinical cardiology 40, no. 9 (September 2017): 746-751.

PMID
28543401
Full Text

Echouffo-Tcheugui, JB, Shrader, P, Thomas, L, Gersh, BJ, Kowey, PR, Mahaffey, KW, Singer, DE, Hylek, EM, Go, AS, Peterson, ED, Piccini, JP, and Fonarow, GC. "Care Patterns and Outcomes in Atrial Fibrillation Patients With and Without Diabetes: ORBIT-AF Registry." Journal of the American College of Cardiology 70, no. 11 (September 2017): 1325-1335.

PMID
28882229
Full Text

Pages