Jonathan Paul Piccini, MD

Associate Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail Dept Of Medicine, Durham, NC 27710
Phone (919) 684-8111
Email address jonathan.piccini@duke.edu

Jonathan P. Piccini, MD, MHS is a clinical cardiac electrophysiologist and Associate Professor of Medicine at Duke University Medical Center and the Duke Clinical Research Institute. His research interests include the conduct of clinical trials and the assessment of cardiovascular therapeutics for the care of patients with heart rhythm disorders. At present, he is the Director of the EP Clinical Trials Program and Arrhythmia Core Laboratory at Duke University. He also serves on the Clinical Working Group of the American Heart Association’s Get With The Guidelines – Atrial fibrillation (GWTG-Afib) registry program. He is an associate editor for the American Heart Journal and serves on the editorial board of Heart Rhythm, the European Heart Journal, and the Journal of Cardiac Electrophysiology. He is the Principal Investigator of the data and coordinating center for ORBIT AF, a 25,000 patient registry focused on quality of care and improving outcomes in patients with atrial fibrillation. He is also the PI of the GENETIC AF clinical trial, the first clinical trial to study genotype-directed rhythm control therapy for atrial fibrillation. He also serves on the steering committees of multiple international randomized trials focused on the treatment of atrial fibrillation.  Dr. Piccini has more than 175 publications in the field of heart rhythm medicine. Clinically, his focus is on the care of patients with atrial fibrillation and complex arrhythmias, with particular emphasis on catheter ablation and lead extraction.

Education and Training

  • Clinical Cardiac Electrophysiology Fellowship, Medicine, Duke University School of Medicine, 2009 - 2011
  • Cardiology Fellowship, Medicine, Duke University School of Medicine, 2005 - 2009
  • Internal Medicine Residency, Medicine, Johns Hopkins University School of Medicine, 2002 - 2005
  • M.H.S., Duke University, 2009
  • M.D., Northwestern University Feinberg School of Medicine, 2002

Publications

Piccini, JP, Connolly, SJ, Abraham, WT, Healey, JS, Steinberg, BA, Al-Khalidi, HR, Dignacco, P, van Veldhuisen, DJ, Sauer, WH, White, M, Wilton, SB, Anand, IS, Dufton, C, Marshall, DA, Aleong, RG, Davis, GW, Clark, RL, Emery, LL, and Bristow, MR. "A genotype-directed comparative effectiveness trial of Bucindolol and metoprolol succinate for prevention of symptomatic atrial fibrillation/atrial flutter in patients with heart failure: Rationale and design of the GENETIC-AF trial (Accepted)." American Heart Journal 199 (May 1, 2018): 51-58.

Full Text

Barnett, AS, Cyr, DD, Goodman, SG, Levitan, BS, Yuan, Z, Hankey, GJ, Singer, DE, Becker, RC, Breithardt, G, Berkowitz, SD, Halperin, JL, Hacke, W, Mahaffey, KW, Nessel, CC, Fox, KAA, Patel, MR, and Piccini, JP. "Net clinical benefit of rivaroxaban compared with warfarin in atrial fibrillation: Results from ROCKET AF." International journal of cardiology 257 (April 2018): 78-83.

PMID
29506743
Full Text

Kaufman, BG, Kim, S, Pieper, K, Allen, LA, Gersh, BJ, Naccarelli, GV, Ezekowitz, MD, Fonarow, GC, Mahaffey, KW, Singer, DE, Chan, PS, Freeman, JV, Ansell, J, Kowey, PR, Rieffel, JA, Piccini, J, Peterson, E, and O'Brien, EC. "Disease understanding in patients newly diagnosed with atrial fibrillation." Heart (British Cardiac Society) 104, no. 6 (March 2018): 494-501.

PMID
28790169
Full Text

Steinberg, BA, Shrader, P, Pieper, K, Thomas, L, Allen, LA, Ansell, J, Chan, PS, Ezekowitz, MD, Fonarow, GC, Freeman, JV, Gersh, BJ, Kowey, PR, Mahaffey, KW, Naccarelli, GV, Reiffel, JA, Singer, DE, Peterson, ED, Piccini, JP, and Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT‐AF) II Investigators, . "Frequency and Outcomes of Reduced Dose Non-Vitamin K Antagonist Anticoagulants: Results From ORBIT-AF II (The Outcomes Registry for Better Informed Treatment of Atrial Fibrillation II)." Journal of the American Heart Association 7, no. 4 (February 16, 2018).

PMID
29453305
Full Text

Dan, G-A, Martinez-Rubio, A, Agewall, S, Boriani, G, Borggrefe, M, Gaita, F, van Gelder, I, Gorenek, B, Kaski, JC, Kjeldsen, K, Lip, GYH, Merkely, B, Okumura, K, Piccini, JP, Potpara, T, Poulsen, BK, Saba, M, Savelieva, I, Tamargo, JL, Wolpert, C, and ESC Scientific Document Group , . "Antiarrhythmic drugs-clinical use and clinical decision making: a consensus document from the European Heart Rhythm Association (EHRA) and European Society of Cardiology (ESC) Working Group on Cardiovascular Pharmacology, endorsed by the Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS) and International Society of Cardiovascular Pharmacotherapy (ISCP)." Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology (February 9, 2018).

PMID
29438514
Full Text

Piccini, JP, and Kirchhof, P. "Improving outcomes after catheter ablation of atrial fibrillation: better patient selection, better procedure, or both?." European heart journal 39, no. 6 (February 2018): 450-452.

PMID
29182747
Full Text

Piccini, JP, and Jones, WS. "Dual Antithrombotic Therapy with Dabigatran after PCI in Atrial Fibrillation." The New England journal of medicine 378, no. 5 (February 2018): 486-. (Letter)

PMID
29411956
Full Text

Echouffo-Tcheugui, JB, Shrader, P, Thomas, L, Piccini, JP, and Fonarow, GC. "Reply: Graphing Ratio Measures on Forest Plot." Journal of the American College of Cardiology 71, no. 5 (February 2018): 586-. (Letter)

PMID
29406872
Full Text

Sugrue, A, Siontis, KC, Piccini, JP, and Noseworthy, PA. "Periprocedural Anticoagulation Management for Atrial Fibrillation Ablation: Current Knowledge and Future Directions." Current treatment options in cardiovascular medicine 20, no. 1 (January 25, 2018): 3-. (Review)

PMID
29368193
Full Text

Friedman, DJ, and Piccini, JP. "Predicting AF recurrence after catheter ablation: Is it time to use the force?." Journal of cardiovascular electrophysiology (January 2, 2018).

PMID
29292862
Full Text

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