Jonathan Paul Piccini, MD

Associate Professor of Medicine
Associate Professor in Population Health Sciences
Member in the Duke Clinical Research Institute
Campus mail Dept of Medicine, Durham, NC 27710
Phone (919) 684-8111
Email address jonathan.piccini@duke.edu

Jonathan P. Piccini, MD, MHS is a clinical cardiac electrophysiologist and Associate Professor of Medicine at Duke University Medical Center and the Duke Clinical Research Institute. His research interests include the conduct of clinical trials and the assessment of cardiovascular therapeutics for the care of patients with heart rhythm disorders. At present, he is the Director of the EP Clinical Trials Program and Arrhythmia Core Laboratory at Duke University. He also serves on the Clinical Working Group of the American Heart Association’s Get With The Guidelines – Atrial fibrillation (GWTG-Afib) registry program. He is an associate editor for the American Heart Journal and serves on the editorial board of Heart Rhythm, the European Heart Journal, and the Journal of Cardiac Electrophysiology. He is the Principal Investigator of the data and coordinating center for ORBIT AF, a 25,000 patient registry focused on quality of care and improving outcomes in patients with atrial fibrillation. He is also the PI of the GENETIC AF clinical trial, the first clinical trial to study genotype-directed rhythm control therapy for atrial fibrillation. He also serves on the steering committees of multiple international randomized trials focused on the treatment of atrial fibrillation.  Dr. Piccini has more than 175 publications in the field of heart rhythm medicine. Clinically, his focus is on the care of patients with atrial fibrillation and complex arrhythmias, with particular emphasis on catheter ablation and lead extraction.

Education and Training

  • Clinical Cardiac Electrophysiology Fellowship, Medicine, Duke University School of Medicine, 2009 - 2011
  • Cardiology Fellowship, Medicine, Duke University School of Medicine, 2005 - 2009
  • Internal Medicine Residency, Medicine, Johns Hopkins University School of Medicine, 2002 - 2005
  • M.H.S., Duke University, 2009
  • M.D., Northwestern University, Feinberg School of Medicine, 2002

Publications

Wosik, Jedrek, Megan E. B. Clowse, Robert Overton, Bhargav Adagarla, Nicoleta Economou-Zavlanos, Joanna Cavalier, Ricardo Henao, et al. “Impact of the COVID-19 pandemic on patterns of outpatient cardiovascular care.” Am Heart J 231 (January 2021): 1–5. https://doi.org/10.1016/j.ahj.2020.10.074.

PMID
33137309
Full Text

Carnicelli, Anthony P., Hwanhee Hong, Robert P. Giugliano, Stuart J. Connolly, John Eikelboom, Manesh R. Patel, Lars Wallentin, et al. “Individual Patient Data from the Pivotal Randomized Controlled Trials of Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation (COMBINE AF): Design and Rationale: From the COMBINE AF (A COllaboration between Multiple institutions to Better Investigate Non-vitamin K antagonist oral anticoagulant usE in Atrial Fibrillation) Investigators.” Am Heart J, December 6, 2020. https://doi.org/10.1016/j.ahj.2020.12.002.

PMID
33296688
Full Text

Bondonno, Nicola P., Kevin Murray, Catherine P. Bondonno, Joshua R. Lewis, Kevin D. Croft, Cecilie Kyrø, Gunnar Gislason, et al. “Flavonoid intake and its association with atrial fibrillation.” Clin Nutr 39, no. 12 (December 2020): 3821–28. https://doi.org/10.1016/j.clnu.2020.04.025.

PMID
32386860
Full Text

Fudim, Marat, Yawar J. Qadri, Kamrouz Ghadimi, David B. MacLeod, Jeroen Molinger, Jonathan P. Piccini, John Whittle, Paul E. Wischmeyer, Manesh R. Patel, and Luis Ulloa. “Implications for Neuromodulation Therapy to Control Inflammation and Related Organ Dysfunction in COVID-19.” J Cardiovasc Transl Res 13, no. 6 (December 2020): 894–99. https://doi.org/10.1007/s12265-020-10031-6.

PMID
32458400
Full Text

Garweg, Christophe, Surinder Kaur Khelae, Clemens Steinwender, Joseph Yat Sun Chan, Philippe Ritter, Jens Brock Johansen, Venkata Sagi, et al. “Predictors of atrial mechanical sensing and atrioventricular synchrony with a leadless ventricular pacemaker: Results from the MARVEL 2 Study.” Heart Rhythm 17, no. 12 (December 2020): 2037–45. https://doi.org/10.1016/j.hrthm.2020.07.024.

PMID
32717315
Full Text

Garg, Aatish, Jayanthi N. Koneru, Dedra H. Fagan, Kurt Stromberg, Santosh K. Padala, Mikhael F. El-Chami, Paul R. Roberts, Jonathan P. Piccini, Alan Cheng, and Kenneth A. Ellenbogen. “Morbidity and mortality in patients precluded for transvenous pacemaker implantation: Experience with a leadless pacemaker.” Heart Rhythm 17, no. 12 (December 2020): 2056–63. https://doi.org/10.1016/j.hrthm.2020.07.035.

PMID
32763431
Full Text

Field, Michael E., Michael R. Gold, Motiur Rahman, Laura Goldstein, Sonia Maccioni, Abhishek Srivastava, Rahul Khanna, Jonathan P. Piccini, and Daniel J. Friedman. “Healthcare utilization and cost in patients with atrial fibrillation and heart failure undergoing catheter ablation.” J Cardiovasc Electrophysiol 31, no. 12 (December 2020): 3166–75. https://doi.org/10.1111/jce.14774.

PMID
33022815
Full Text

Piccini, Jonathan P., Derick M. Todd, Tyler Massaro, Aimee Lougee, Karl Georg Haeusler, Benjamin Blank, Joseph Paul de Bono, et al. “Changes in quality of life, cognition and functional status following catheter ablation of atrial fibrillation.” Heart 106, no. 24 (December 2020): 1919–26. https://doi.org/10.1136/heartjnl-2020-316612.

PMID
33046527
Full Text

Loring, Zak, Rebecca North, Anne S. Hellkamp, Brett D. Atwater, Camille G. Frazier-Mills, Kevin P. Jackson, Sean D. Pokorney, Gervasio A. Lamas, and Jonathan P. Piccini. “VVI pacing with normal QRS duration and ventricular function: MOST trial findings relevant to leadless pacemakers.” Pacing Clin Electrophysiol 43, no. 12 (December 2020): 1461–66. https://doi.org/10.1111/pace.14100.

PMID
33085123
Full Text

Zenger, Brian, Mingyuan Zhang, Ann Lyons, T Jared Bunch, James C. Fang, Roger A. Freedman, Leenhapong Navaravong, et al. “Patient-reported outcomes and subsequent management in atrial fibrillation clinical practice: Results from the Utah mEVAL AF program.” J Cardiovasc Electrophysiol 31, no. 12 (December 2020): 3187–95. https://doi.org/10.1111/jce.14795.

PMID
33124710
Full Text

Pages