Jonathan Paul Piccini, MD

Associate Professor of Medicine
Associate Professor in Population Health Sciences
Member in the Duke Clinical Research Institute
Campus mail Dept of Medicine, Durham, NC 27710
Phone (919) 684-8111
Email address jonathan.piccini@duke.edu

Jonathan P. Piccini, MD, MHS is a clinical cardiac electrophysiologist and Associate Professor of Medicine at Duke University Medical Center and the Duke Clinical Research Institute. His research interests include the conduct of clinical trials and the assessment of cardiovascular therapeutics for the care of patients with heart rhythm disorders. At present, he is the Director of the EP Clinical Trials Program and Arrhythmia Core Laboratory at Duke University. He also serves on the Clinical Working Group of the American Heart Association’s Get With The Guidelines – Atrial fibrillation (GWTG-Afib) registry program. He is an associate editor for the American Heart Journal and serves on the editorial board of Heart Rhythm, the European Heart Journal, and the Journal of Cardiac Electrophysiology. He is the Principal Investigator of the data and coordinating center for ORBIT AF, a 25,000 patient registry focused on quality of care and improving outcomes in patients with atrial fibrillation. He is also the PI of the GENETIC AF clinical trial, the first clinical trial to study genotype-directed rhythm control therapy for atrial fibrillation. He also serves on the steering committees of multiple international randomized trials focused on the treatment of atrial fibrillation.  Dr. Piccini has more than 175 publications in the field of heart rhythm medicine. Clinically, his focus is on the care of patients with atrial fibrillation and complex arrhythmias, with particular emphasis on catheter ablation and lead extraction.

Education and Training

  • Clinical Cardiac Electrophysiology Fellowship, Medicine, Duke University School of Medicine, 2009 - 2011
  • Cardiology Fellowship, Medicine, Duke University School of Medicine, 2005 - 2009
  • Internal Medicine Residency, Medicine, Johns Hopkins University School of Medicine, 2002 - 2005
  • M.H.S., Duke University, 2009
  • M.D., Northwestern University Feinberg School of Medicine, 2002

Publications

Wang, A., J. B. Green, J. L. Halperin, and J. P. Piccini. “Atrial Fibrillation and Diabetes Mellitus: JACC Review Topic of the Week.” Journal of the American College of Cardiology 74, no. 8 (August 27, 2019): 1107–15. https://doi.org/10.1016/j.jacc.2019.07.020.

Full Text

El-Chami, Mikhael F., Kyoko Soejima, Jonathan P. Piccini, Dwight Reynolds, Philippe Ritter, Toshimasa Okabe, Paul A. Friedman, et al. “Incidence and outcomes of systemic infections in patients with leadless pacemakers: Data from the Micra IDE study..” Pacing Clin Electrophysiol 42, no. 8 (August 2019): 1105–10. https://doi.org/10.1111/pace.13752.

PMID
31232461
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Pokorney, Sean D., DaJuanicia N. Holmes, Laine Thomas, Gregg C. Fonarow, Peter R. Kowey, James A. Reiffel, Daniel E. Singer, et al. “Association Between Warfarin Control Metrics and Atrial Fibrillation Outcomes in the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation..” Jama Cardiol, July 3, 2019. https://doi.org/10.1001/jamacardio.2019.1960.

PMID
31268487
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Fudim, Marat, Mouhammad Fathallah, Linda K. Shaw, Peter R. Liu, Olga James, Zainab Samad, Jonathan P. Piccini, Paul L. Hess, and Salvador Borges-Neto. “The Prognostic Value of Diastolic and Systolic Mechanical Left Ventricular Dyssynchrony Among Patients With Coronary Heart Disease..” In Jacc Cardiovasc Imaging, 12:1215–26, 2019. https://doi.org/10.1016/j.jcmg.2018.05.018.

PMID
30031704
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Piccini, Jonathan P., William T. Abraham, Christopher Dufton, Ian A. Carroll, Jeff S. Healey, Dirk J. van Veldhuisen, William H. Sauer, et al. “Bucindolol for the Maintenance of Sinus Rhythm in a Genotype-Defined HF Population: The GENETIC-AF Trial..” Jacc Heart Fail 7, no. 7 (July 2019): 586–98. https://doi.org/10.1016/j.jchf.2019.04.004.

PMID
31042551
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Inohara, Taku, Peter Shrader, Karen Pieper, Rosalia G. Blanco, Larry A. Allen, Gregg C. Fonarow, Bernard J. Gersh, et al. “Treatment of atrial fibrillation with concomitant coronary or peripheral artery disease: Results from the outcomes registry for better informed treatment of atrial fibrillation II..” Am Heart J 213 (July 2019): 81–90. https://doi.org/10.1016/j.ahj.2019.04.007.

PMID
31129441
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Inohara, Taku, Jonathan P. Piccini, Kenneth W. Mahaffey, Takehiro Kimura, Yoshinori Katsumata, Kojiro Tanimoto, Kohei Inagawa, et al. “A Cluster Analysis of the Japanese Multicenter Outpatient Registry of Patients With Atrial Fibrillation..” Am J Cardiol, June 25, 2019. https://doi.org/10.1016/j.amjcard.2019.05.071.

PMID
31350002
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Thomas, Laine E., Emily C. O’Brien, Jonathan P. Piccini, Ralph B. D’Agostino, and Michael J. Pencina. “Application of net reclassification index to non-nested and point-based risk prediction models: a review..” Eur Heart J 40, no. 23 (June 14, 2019): 1880–87. https://doi.org/10.1093/eurheartj/ehy345.

PMID
29955849
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Friedman, Daniel J., Stephen J. Greene, Jonathan P. Piccini, Sreekanth Vemulapalli, and Kevin P. Jackson. “Watchman implantation in a patient with left atrial appendage thrombus..” J Cardiovasc Electrophysiol, June 13, 2019. https://doi.org/10.1111/jce.14031.

PMID
31192503
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