Jonathan Paul Piccini, MD

Associate Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail Dept Of Medicine, Durham, NC 27710
Phone (919) 684-8111
Email address jonathan.piccini@duke.edu

Jonathan P. Piccini, MD, MHS is a clinical cardiac electrophysiologist and Associate Professor of Medicine at Duke University Medical Center and the Duke Clinical Research Institute. His research interests include the conduct of clinical trials and the assessment of cardiovascular therapeutics for the care of patients with heart rhythm disorders. At present, he is the Director of the EP Clinical Trials Program and Arrhythmia Core Laboratory at Duke University. He also serves on the Clinical Working Group of the American Heart Association’s Get With The Guidelines – Atrial fibrillation (GWTG-Afib) registry program. He is an associate editor for the American Heart Journal and serves on the editorial board of Heart Rhythm, the European Heart Journal, and the Journal of Cardiac Electrophysiology. He is the Principal Investigator of the data and coordinating center for ORBIT AF, a 25,000 patient registry focused on quality of care and improving outcomes in patients with atrial fibrillation. He is also the PI of the GENETIC AF clinical trial, the first clinical trial to study genotype-directed rhythm control therapy for atrial fibrillation. He also serves on the steering committees of multiple international randomized trials focused on the treatment of atrial fibrillation.  Dr. Piccini has more than 175 publications in the field of heart rhythm medicine. Clinically, his focus is on the care of patients with atrial fibrillation and complex arrhythmias, with particular emphasis on catheter ablation and lead extraction.

Education and Training

  • Clinical Cardiac Electrophysiology Fellowship, Medicine, Duke University School of Medicine, 2009 - 2011
  • Cardiology Fellowship, Medicine, Duke University School of Medicine, 2005 - 2009
  • Internal Medicine Residency, Medicine, Johns Hopkins University School of Medicine, 2002 - 2005
  • M.H.S., Duke University, 2009
  • M.D., Northwestern University Feinberg School of Medicine, 2002

Publications

Vora, AN, Dai, D, Matsuoka, R, Harrison, JK, Hughes, GC, Sherwood, MW, Piccini, JP, Bhardwaj, B, Lopes, RD, Cohen, D, Holmes, DR, Thourani, VH, Peterson, E, Kirtane, A, Kapadia, S, and Vemulapalli, S. "Incidence, Management, and Associated Clinical Outcomes of New-Onset Atrial Fibrillation Following Transcatheter Aortic Valve Replacement: An Analysis From the STS/ACC TVT Registry." Jacc. Cardiovascular Interventions 11, no. 17 (September 2018): 1746-1756.

PMID
30190063
Full Text

Gaeta, S, Schroder, JN, Daneshmand, MA, Thomas, KL, Hegland, DD, Piccini, JP, Daubert, JP, Koontz, JI, and Sun, AY. "Catheter Ablation of Mid-Myocardial Ventricular Tachycardia by Simultaneous Unipolar Radiofrequency Ablation With Half-Normal Saline Irrigation." Jacc. Clinical Electrophysiology 4, no. 9 (September 2018): 1263-1264.

PMID
30236404
Full Text

Thind, M, Holmes, DN, Badri, M, Pieper, KS, Singh, A, Blanco, RG, Steinberg, B, Fonarow, GC, Gersh, BJ, Mahaffey, KW, Peterson, ED, Reiffel, JA, Piccini, JP, Kowey, PR, and ORBIT-AF Investigators and Patients, . "Embolic and Other Adverse Outcomes in Symptomatic Versus Asymptomatic Patients With Atrial Fibrillation (from the ORBIT-AF Registry)." The American Journal of Cardiology (August 20, 2018).

PMID
30227964
Full Text

Quinn, GR, Hellkamp, AS, Hankey, GJ, Becker, RC, Berkowitz, SD, Breithardt, G, Fava, M, Fox, KAA, Halperin, JL, Mahaffey, KW, Nessel, CC, Patel, MR, Piccini, JP, and Singer, DE. "Selective serotonin reuptake inhibitors and bleeding risk in anticoagulated patients with atrial fibrillation: An analysis from the ROCKET AF trial." August 1, 2018.

Full Text

Jackson, LR, Kim, S, Fonarow, GC, Freeman, JV, Gersh, BJ, Go, AS, Hylek, EM, Kowey, PR, Mahaffey, KW, Singer, D, Thomas, L, Blanco, R, Peterson, ED, and Piccini, JP. "Stroke risk and treatment in patients with atrial fibrillation and low CHA2DS2-VASC scores: Findings from the ORBIT-AF I and II registries." Journal of the American Heart Association 7, no. 16 (August 1, 2018).

Full Text

Kirchhof, P, Haeusler, KG, Blank, B, De Bono, J, Callans, D, Elvan, A, Fetsch, T, Van Gelder, IC, Gentlesk, P, Grimaldi, M, Hansen, J, Hindricks, G, Al-Khalidi, HR, Massaro, T, Mont, L, Nielsen, JC, Nölker, G, Piccini, JP, De Potter, T, Scherr, D, Schotten, U, Themistoclakis, S, Todd, D, Vijgen, J, and Di Biase, L. "Apixaban in patients at risk of stroke undergoing atrial fibrillation ablation." European Heart Journal 39, no. 32 (August 2018): 2942-2955.

PMID
29579168
Full Text

DeVore, AD, and Piccini, JP. "Mineralocorticoid Receptor Antagonism for the Treatment of AF and HFpEF: Preserving Hope." Jacc. Heart Failure 6, no. 8 (August 2018): 698-700.

PMID
30078393
Full Text

Zareba, W, Daubert, JP, Beck, CA, Huang, DT, Alexis, JD, Brown, MW, Pyykkonen, K, McNitt, S, Oakes, D, Feng, C, Aktas, MK, Ayala-Parades, F, Baranchuk, A, Dubuc, M, Haigney, M, Mazur, A, McPherson, CA, Mitchell, LB, Natale, A, Piccini, JP, Raitt, M, Rashtian, MY, Schuger, C, Winters, S, Worley, SJ, Ziv, O, Moss, AJ, and RAID Trial Investigators, . "Ranolazine in High-Risk Patients With Implanted Cardioverter-Defibrillators: The RAID Trial." Journal of the American College of Cardiology 72, no. 6 (August 2018): 636-645.

PMID
30071993
Full Text

Piccini, JP, and Calkins, H. "Catheter ablation of rotational activity in atrial fibrillation: A barren oasis?." American Heart Journal (July 31, 2018).

PMID
30219196
Full Text

Piccini, JP, Pokorney, SD, Anstrom, KJ, Oldenburg, O, Punjabi, NM, Fiuzat, M, Tasissa, G, Whellan, DJ, Lindenfeld, J, Benjafield, A, Woehrle, H, Blase, A, and O'Connor, CM. "Adaptive servo-ventilation reduces atrial fibrillation burden in patients with heart failure and sleep apnea." Heart Rhythm (July 27, 2018).

PMID
30059750
Full Text

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