Jonathan Paul Piccini, MD

Associate Professor of Medicine
Associate Professor in Population Health Sciences
Member in the Duke Clinical Research Institute
Campus mail Dept of Medicine, Durham, NC 27710
Phone (919) 684-8111
Email address jonathan.piccini@duke.edu

Jonathan P. Piccini, MD, MHS is a clinical cardiac electrophysiologist and Associate Professor of Medicine at Duke University Medical Center and the Duke Clinical Research Institute. His research interests include the conduct of clinical trials and the assessment of cardiovascular therapeutics for the care of patients with heart rhythm disorders. At present, he is the Director of the EP Clinical Trials Program and Arrhythmia Core Laboratory at Duke University. He also serves on the Clinical Working Group of the American Heart Association’s Get With The Guidelines – Atrial fibrillation (GWTG-Afib) registry program. He is an associate editor for the American Heart Journal and serves on the editorial board of Heart Rhythm, the European Heart Journal, and the Journal of Cardiac Electrophysiology. He is the Principal Investigator of the data and coordinating center for ORBIT AF, a 25,000 patient registry focused on quality of care and improving outcomes in patients with atrial fibrillation. He is also the PI of the GENETIC AF clinical trial, the first clinical trial to study genotype-directed rhythm control therapy for atrial fibrillation. He also serves on the steering committees of multiple international randomized trials focused on the treatment of atrial fibrillation.  Dr. Piccini has more than 175 publications in the field of heart rhythm medicine. Clinically, his focus is on the care of patients with atrial fibrillation and complex arrhythmias, with particular emphasis on catheter ablation and lead extraction.

Education and Training

  • Clinical Cardiac Electrophysiology Fellowship, Medicine, Duke University School of Medicine, 2009 - 2011
  • Cardiology Fellowship, Medicine, Duke University School of Medicine, 2005 - 2009
  • Internal Medicine Residency, Medicine, Johns Hopkins University School of Medicine, 2002 - 2005
  • M.H.S., Duke University, 2009
  • M.D., Northwestern University, Feinberg School of Medicine, 2002

Publications

Friedman, Daniel J., Jed A. Overmann, Jeffrey M. Fish, Stephen A. Gaeta, John H. Tranter, Riki Thao, and Jonathan P. Piccini. “Impact of interruptions in radiofrequency energy delivery on lesion characteristics.” Heart Rhythm 17, no. 8 (August 2020): 1354–59. https://doi.org/10.1016/j.hrthm.2020.03.008.

PMID
32200047
Full Text

Pokorney, Sean D., Eric Black-Maier, and Jonathan P. Piccini. “Reply: Oral Anticoagulation and Cardiovascular Outcomes in Patients With Atrial Fibrillation and End-Stage Renal Disease.” J Am Coll Cardiol 76, no. 3 (July 21, 2020): 351–52. https://doi.org/10.1016/j.jacc.2020.05.035.

PMID
32674801
Full Text

Noseworthy, Peter A., Holly K. Van Houten, Bernard J. Gersh, Douglas L. Packer, Paul A. Friedman, Nilay D. Shah, Shannon M. Dunlay, Konstantinos C. Siontis, Jonathan P. Piccini, and Xiaoxi Yao. “Generalizability of the CASTLE-AF trial: Catheter ablation for patients with atrial fibrillation and heart failure in routine practice.” Heart Rhythm 17, no. 7 (July 2020): 1057–65. https://doi.org/10.1016/j.hrthm.2020.02.030.

PMID
32145348
Full Text

Rehorn, Michael R., Jason Koontz, Adam S. Barnett, Eric Black-Maier, Jonathan P. Piccini, Zak Loring, Jacob Schroder, and Albert Y. Sun. “Noninvasive electrocardiographic mapping of ventricular tachycardia in a patient with a left ventricular assist device.” Heartrhythm Case Rep 6, no. 7 (July 2020): 398–401. https://doi.org/10.1016/j.hrcr.2020.03.015.

PMID
32695586
Full Text

Loungani, Rahul S., Michael R. Rehorn, L Kristin Newby, Jason N. Katz, Igor Klem, Robert J. Mentz, W Schuyler Jones, et al. “A care pathway for the cardiovascular complications of COVID-19: Insights from an institutional response.” Am Heart J 225 (July 2020): 3–9. https://doi.org/10.1016/j.ahj.2020.04.024.

PMID
32417526
Full Text

Friedman, Daniel J., Rahul Khanna, and Jonathan P. Piccini. “Reply: Intracardiac Versus Transesophageal Echocardiography: If You Don't Compare Them You Don't Have the Answer.” Jacc Clin Electrophysiol 6, no. 7 (July 2020): 881–82. https://doi.org/10.1016/j.jacep.2020.05.014.

PMID
32703576
Full Text

Kloosterman, Mariëlle, Winnie Chua, Larissa Fabritz, Hussein R. Al-Khalidi, Ulrich Schotten, Jens C. Nielsen, Jonathan P. Piccini, et al. “Sex differences in catheter ablation of atrial fibrillation: results from AXAFA-AFNET 5.” Europace 22, no. 7 (July 1, 2020): 1026–35. https://doi.org/10.1093/europace/euaa015.

PMID
32142113
Full Text

Lewis, Robert K., Sean D. Pokorney, Donald D. Hegland, and Jonathan P. Piccini. “Hands on: How to approach patients undergoing lead extraction.” J Cardiovasc Electrophysiol 31, no. 7 (July 2020): 1801–8. https://doi.org/10.1111/jce.14244.

PMID
31626390
Full Text

Terricabras, Maria, Jonathan P. Piccini, and Atul Verma. “Ablation of persistent atrial fibrillation: Challenges and solutions.” J Cardiovasc Electrophysiol 31, no. 7 (July 2020): 1809–21. https://doi.org/10.1111/jce.14311.

PMID
31828883
Full Text

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