Jonathan Paul Piccini, MD

Associate Professor of Medicine
Associate Professor in Population Health Sciences
Member in the Duke Clinical Research Institute
Campus mail Dept of Medicine, Durham, NC 27710
Phone (919) 684-8111
Email address jonathan.piccini@duke.edu

Jonathan P. Piccini, MD, MHS is a clinical cardiac electrophysiologist and Associate Professor of Medicine at Duke University Medical Center and the Duke Clinical Research Institute. His research interests include the conduct of clinical trials and the assessment of cardiovascular therapeutics for the care of patients with heart rhythm disorders. At present, he is the Director of the EP Clinical Trials Program and Arrhythmia Core Laboratory at Duke University. He also serves on the Clinical Working Group of the American Heart Association’s Get With The Guidelines – Atrial fibrillation (GWTG-Afib) registry program. He is an associate editor for the American Heart Journal and serves on the editorial board of Heart Rhythm, the European Heart Journal, and the Journal of Cardiac Electrophysiology. He is the Principal Investigator of the data and coordinating center for ORBIT AF, a 25,000 patient registry focused on quality of care and improving outcomes in patients with atrial fibrillation. He is also the PI of the GENETIC AF clinical trial, the first clinical trial to study genotype-directed rhythm control therapy for atrial fibrillation. He also serves on the steering committees of multiple international randomized trials focused on the treatment of atrial fibrillation.  Dr. Piccini has more than 175 publications in the field of heart rhythm medicine. Clinically, his focus is on the care of patients with atrial fibrillation and complex arrhythmias, with particular emphasis on catheter ablation and lead extraction.

Education and Training

  • Clinical Cardiac Electrophysiology Fellowship, Medicine, Duke University School of Medicine, 2009 - 2011
  • Cardiology Fellowship, Medicine, Duke University School of Medicine, 2005 - 2009
  • Internal Medicine Residency, Medicine, Johns Hopkins University School of Medicine, 2002 - 2005
  • M.H.S., Duke University, 2009
  • M.D., Northwestern University Feinberg School of Medicine, 2002

Publications

Ungar, Leo, Fatima Rodriguez, Anne S. Hellkamp, Richard C. Becker, Scott D. Berkowitz, Guenter Breithardt, Keith A. A. Fox, et al. “Patient-Reported Satisfaction and Study Drug Discontinuation: Post-Hoc Analysis of Findings from ROCKET AF..” Cardiol Ther 8, no. 2 (December 2019): 283–95. https://doi.org/10.1007/s40119-019-00146-6.

PMID
31376090
Full Text

Piccini, Jonathan P., Kurt Stromberg, Kevin P. Jackson, Robert C. Kowal, Gabor Z. Duray, Mikhael F. El-Chami, George H. Crossley, et al. “Patient selection, pacing indications, and subsequent outcomes with de novo leadless single-chamber VVI pacing..” Europace 21, no. 11 (November 1, 2019): 1686–93. https://doi.org/10.1093/europace/euz230.

PMID
31681964
Full Text

Black-Maier, Eric, Alice Parish, Benjamin A. Steinberg, Cynthia L. Green, Zak Loring, Adam S. Barnett, Sana M. Al-Khatib, et al. “Predicting atrial fibrillation recurrence after ablation in patients with heart failure: Validity of the APPLE and CAAP-AF risk scoring systems..” Pacing Clin Electrophysiol 42, no. 11 (November 2019): 1440–47. https://doi.org/10.1111/pace.13805.

PMID
31544956
Full Text

Choi, Jong-Il, Yong Soo Baek, Seung Young Roh, Jonathan P. Piccini, and Young-Hoon Kim. “Chromosome 4q25 variants and biomarkers of myocardial fibrosis in patients with atrial fibrillation..” J Cardiovasc Electrophysiol 30, no. 10 (October 2019): 1904–13. https://doi.org/10.1111/jce.14104.

PMID
31393025
Full Text

Fudim, Marat, Nathan H. Waldron, and Jonathan P. Piccini. “Epicardial ganglionated plexus ablation: Safety considerations beyond the atria..” J Cardiovasc Electrophysiol 30, no. 10 (October 2019): 2189–90. https://doi.org/10.1111/jce.14095.

PMID
31389095
Full Text

Inohara, Taku, Jonathan P. Piccini, Kenneth W. Mahaffey, Takehiro Kimura, Yoshinori Katsumata, Kojiro Tanimoto, Kohei Inagawa, et al. “A Cluster Analysis of the Japanese Multicenter Outpatient Registry of Patients With Atrial Fibrillation..” Am J Cardiol 124, no. 6 (September 15, 2019): 871–78. https://doi.org/10.1016/j.amjcard.2019.05.071.

PMID
31350002
Full Text

Black-Maier, Eric, Jonathan P. Piccini, and Christopher B. Granger. “Left atrial appendage closure: A therapy uniquely suited for specific populations of patients with atrial fibrillation..” J Cardiovasc Electrophysiol, September 13, 2019. https://doi.org/10.1111/jce.14182.

PMID
31520437
Full Text

Friedman, Daniel J., Stephen J. Greene, Jonathan P. Piccini, Sreekanth Vemulapalli, and Kevin P. Jackson. “Watchman implantation in a patient with left atrial appendage thrombus..” J Cardiovasc Electrophysiol 30, no. 9 (September 2019): 1694–95. https://doi.org/10.1111/jce.14031.

PMID
31192503
Full Text

Pages