Jonathan Paul Piccini, MD

Associate Professor of Medicine
Associate Professor in Population Health Sciences
Member in the Duke Clinical Research Institute
Campus mail Dept Of Medicine, Durham, NC 27710
Phone (919) 684-8111
Email address jonathan.piccini@duke.edu

Jonathan P. Piccini, MD, MHS is a clinical cardiac electrophysiologist and Associate Professor of Medicine at Duke University Medical Center and the Duke Clinical Research Institute. His research interests include the conduct of clinical trials and the assessment of cardiovascular therapeutics for the care of patients with heart rhythm disorders. At present, he is the Director of the EP Clinical Trials Program and Arrhythmia Core Laboratory at Duke University. He also serves on the Clinical Working Group of the American Heart Association’s Get With The Guidelines – Atrial fibrillation (GWTG-Afib) registry program. He is an associate editor for the American Heart Journal and serves on the editorial board of Heart Rhythm, the European Heart Journal, and the Journal of Cardiac Electrophysiology. He is the Principal Investigator of the data and coordinating center for ORBIT AF, a 25,000 patient registry focused on quality of care and improving outcomes in patients with atrial fibrillation. He is also the PI of the GENETIC AF clinical trial, the first clinical trial to study genotype-directed rhythm control therapy for atrial fibrillation. He also serves on the steering committees of multiple international randomized trials focused on the treatment of atrial fibrillation.  Dr. Piccini has more than 175 publications in the field of heart rhythm medicine. Clinically, his focus is on the care of patients with atrial fibrillation and complex arrhythmias, with particular emphasis on catheter ablation and lead extraction.

Education and Training

  • Clinical Cardiac Electrophysiology Fellowship, Medicine, Duke University School of Medicine, 2009 - 2011
  • Cardiology Fellowship, Medicine, Duke University School of Medicine, 2005 - 2009
  • Internal Medicine Residency, Medicine, Johns Hopkins University School of Medicine, 2002 - 2005
  • M.H.S., Duke University, 2009
  • M.D., Northwestern University Feinberg School of Medicine, 2002

Publications

Madhavan, M, Graff-Radford, J, Piccini, JP, and Gersh, BJ. "Cognitive dysfunction in atrial fibrillation.(Accepted)" Nature Reviews. Cardiology 15, no. 12 (December 2018): 744-756. (Review)

PMID
30275499
Full Text

Durheim, MT, Holmes, DN, Blanco, RG, Allen, LA, Chan, PS, Freeman, JV, Fonarow, GC, Go, AS, Hylek, EM, Mahaffey, KW, Pokorney, SD, Reiffel, JA, Singer, DE, Peterson, ED, and Piccini, JP. "Characteristics and outcomes of adults with chronic obstructive pulmonary disease and atrial fibrillation." Heart (British Cardiac Society) 104, no. 22 (November 2018): 1850-1858.

PMID
29875139
Full Text

Jackson, LR, Kim, S, Shrader, P, Blanco, R, Thomas, L, Ezekowitz, MD, Ansell, J, Fonarow, GC, Gersh, BJ, Go, AS, Kowey, PR, Mahaffey, KW, Hylek, EM, Peterson, ED, and Piccini, JP. "Early therapeutic persistence on dabigatran versus warfarin therapy in patients with atrial fibrillation: results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry." Journal of Thrombosis and Thrombolysis 46, no. 4 (November 2018): 435-439.

PMID
30051164
Full Text

Waldron, NH, Cooter, M, Haney, JC, Schroder, JN, Gaca, JG, Lin, SS, Sigurdsson, MI, Fudim, M, Podgoreanu, MV, Stafford-Smith, M, Milano, CA, Piccini, JP, and Mathew, JP. "Temporary autonomic modulation with botulinum toxin type A to reduce atrial fibrillation after cardiac surgery." Heart Rhythm (October 26, 2018).

PMID
30414840
Full Text

Zeitler, EP, Sanders, GD, Singh, K, Greenfield, RA, Gillis, AM, Wilkoff, BL, Piccini, JP, and Al-Khatib, SM. "Single vs. dual chamber implantable cardioverter-defibrillators or programming of implantable cardioverter-defibrillators in patients without a bradycardia pacing indication: systematic review and meta-analysis." Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology 20, no. 10 (October 2018): 1621-1629.

PMID
30137296
Full Text

Luo, N, Xu, H, Jneid, H, Fonarow, GC, Lopes, RD, Piccini, JP, Curtis, AB, Russo, AM, Lewis, WR, Matsouaka, RA, Granger, CB, Mentz, RJ, and Al-Khatib, SM. "Use of Oral Anticoagulation in Eligible Patients Discharged With Heart Failure and Atrial Fibrillation." Circulation. Heart Failure 11, no. 10 (October 2018): e005356-null.

PMID
30354398
Full Text

Inohara, T, Kim, S, Pieper, K, Blanco, RG, Allen, LA, Fonarow, GC, Gersh, BJ, Ezekowitz, MD, Kowey, PR, Reiffel, JA, Naccarelli, GV, Chan, PS, Mahaffey, KW, Singer, DE, Freeman, JV, Steinberg, BA, Peterson, ED, Piccini, JP, and ORBIT AF Patients and Investigators, . "B-type natriuretic peptide, disease progression and clinical outcomes in atrial fibrillation." Heart (British Cardiac Society) (September 18, 2018).

PMID
30228248
Full Text

Vora, AN, Dai, D, Matsuoka, R, Harrison, JK, Hughes, GC, Sherwood, MW, Piccini, JP, Bhardwaj, B, Lopes, RD, Cohen, D, Holmes, DR, Thourani, VH, Peterson, E, Kirtane, A, Kapadia, S, and Vemulapalli, S. "Incidence, Management, and Associated Clinical Outcomes of New-Onset Atrial Fibrillation Following Transcatheter Aortic Valve Replacement: An Analysis From the STS/ACC TVT Registry." Jacc. Cardiovascular Interventions 11, no. 17 (September 2018): 1746-1756.

PMID
30190063
Full Text

Gaeta, S, Schroder, JN, Daneshmand, MA, Thomas, KL, Hegland, DD, Piccini, JP, Daubert, JP, Koontz, JI, and Sun, AY. "Catheter Ablation of Mid-Myocardial Ventricular Tachycardia by Simultaneous Unipolar Radiofrequency Ablation With Half-Normal Saline Irrigation." Jacc. Clinical Electrophysiology 4, no. 9 (September 2018): 1263-1264.

PMID
30236404
Full Text

Washam, JB, Holmes, DN, Thomas, LE, Pokorney, SD, Hylek, EM, Fonarow, GC, Mahaffey, KW, Gersh, BJ, Kowey, PR, Ansell, JE, Go, AS, Reiffel, JA, Freeman, JV, Singer, DE, Naccarelli, G, Blanco, R, Peterson, ED, and Piccini, JP. "Pharmacotherapy for Atrial Fibrillation in Patients With Chronic Kidney Disease: Insights From ORBIT-AF." Journal of the American Heart Association 7, no. 18 (September 2018): e008928-null.

PMID
30371218
Full Text

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