Jonathan Paul Piccini, MD

Associate Professor of Medicine
Associate Professor in Population Health Sciences
Member in the Duke Clinical Research Institute
Campus mail Dept of Medicine, Durham, NC 27710
Phone (919) 684-8111
Email address jonathan.piccini@duke.edu

Jonathan P. Piccini, MD, MHS is a clinical cardiac electrophysiologist and Associate Professor of Medicine at Duke University Medical Center and the Duke Clinical Research Institute. His research interests include the conduct of clinical trials and the assessment of cardiovascular therapeutics for the care of patients with heart rhythm disorders. At present, he is the Director of the EP Clinical Trials Program and Arrhythmia Core Laboratory at Duke University. He also serves on the Clinical Working Group of the American Heart Association’s Get With The Guidelines – Atrial fibrillation (GWTG-Afib) registry program. He is an associate editor for the American Heart Journal and serves on the editorial board of Heart Rhythm, the European Heart Journal, and the Journal of Cardiac Electrophysiology. He is the Principal Investigator of the data and coordinating center for ORBIT AF, a 25,000 patient registry focused on quality of care and improving outcomes in patients with atrial fibrillation. He is also the PI of the GENETIC AF clinical trial, the first clinical trial to study genotype-directed rhythm control therapy for atrial fibrillation. He also serves on the steering committees of multiple international randomized trials focused on the treatment of atrial fibrillation.  Dr. Piccini has more than 175 publications in the field of heart rhythm medicine. Clinically, his focus is on the care of patients with atrial fibrillation and complex arrhythmias, with particular emphasis on catheter ablation and lead extraction.

Education and Training

  • Clinical Cardiac Electrophysiology Fellowship, Medicine, Duke University School of Medicine, 2009 - 2011
  • Cardiology Fellowship, Medicine, Duke University School of Medicine, 2005 - 2009
  • Internal Medicine Residency, Medicine, Johns Hopkins University School of Medicine, 2002 - 2005
  • M.H.S., Duke University, 2009
  • M.D., Northwestern University Feinberg School of Medicine, 2002

Publications

Sutter, Joanne S., Yuliya Lokhnygina, James P. Daubert, Tristram Bahnson, Kevin Jackson, Jason I. Koontz, Albert Y. Sun, et al. “Safety and efficacy outcomes of left atrial posterior wall isolation compared to pulmonary vein isolation and pulmonary vein isolation with linear ablation for the treatment of persistent atrial fibrillation.” Am Heart J 220 (February 2020): 89–96. https://doi.org/10.1016/j.ahj.2019.11.010.

PMID
31805423
Full Text

Pokorney, Sean D., DaJuanicia N. Holmes, Peter Shrader, Laine Thomas, Gregg C. Fonarow, Kenneth W. Mahaffey, Bernard J. Gersh, et al. “Patterns of amiodarone use and outcomes in clinical practice for atrial fibrillation.” Am Heart J 220 (February 2020): 145–54. https://doi.org/10.1016/j.ahj.2019.09.017.

PMID
31812756
Full Text

Black-Maier, Eric, Benjamin A. Steinberg, Kevin M. Trulock, Frances Wang, Yuliya Lokhnygina, Wanda O’Neal, Sana Al-Khatib, et al. “Effectiveness of catheter ablation of atrial fibrillation according to heart failure etiology.” Journal of Arrhythmia 36, no. 1 (February 2020): 84–92. https://doi.org/10.1002/joa3.12291.

PMID
32071625
Full Text

Inohara, Taku, DaJuanicia N. Holmes, Karen Pieper, Rosalia G. Blanco, Larry A. Allen, Gregg C. Fonarow, Bernard J. Gersh, et al. “Decline in renal function and oral anticoagulation dose reduction among patients with atrial fibrillation.” Heart, January 7, 2020. https://doi.org/10.1136/heartjnl-2019-315792.

PMID
31911503
Full Text

Joung, Boyoung, Daniel R. Lexcen, Chi-Keong Ching, Marc T. Silver, Jonathan P. Piccini, Laurence D. Sterns, Rafael Rabinovich, et al. “Additional antitachycardia pacing programming strategies further reduce unnecessary implantable cardioverter-defibrillator shocks.” Heart Rhythm 17, no. 1 (January 2020): 98–105. https://doi.org/10.1016/j.hrthm.2019.07.027.

PMID
31369873
Full Text

Loring, Zak, Peter Shrader, Larry A. Allen, Rosalia Blanco, Paul S. Chan, Michael D. Ezekowitz, Gregg C. Fonarow, et al. “Guideline-directed therapies for comorbidities and clinical outcomes among individuals with atrial fibrillation.” Am Heart J 219 (January 2020): 21–30. https://doi.org/10.1016/j.ahj.2019.10.008.

PMID
31710841
Full Text

Steinwender, Clemens, Surinder Kaur Khelae, Christophe Garweg, Joseph Yat Sun Chan, Philippe Ritter, Jens Brock Johansen, Venkata Sagi, et al. “Atrioventricular Synchronous Pacing Using a Leadless Ventricular Pacemaker: Results From the MARVEL 2 Study.” Jacc Clin Electrophysiol 6, no. 1 (January 2020): 94–106. https://doi.org/10.1016/j.jacep.2019.10.017.

PMID
31709982
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Ikemura, Nobuhiro, John A. Spertus, Takehiro Kimura, Kenneth Mahaffey, Jonathan P. Piccini, Taku Inohara, Ikuko Ueda, et al. “Cohort profile: patient characteristics and quality-of-life measurements for newly-referred patients with atrial fibrillation-Keio interhospital Cardiovascular Studies-atrial fibrillation (KiCS-AF).” Bmj Open 9, no. 12 (December 18, 2019): e032746. https://doi.org/10.1136/bmjopen-2019-032746.

PMID
31857312
Full Text

Kelly, Jacob P., Adam D. DeVore, JingJing Wu, Bradley G. Hammill, Abhinav Sharma, Lauren B. Cooper, G Michael Felker, et al. “Rhythm Control Versus Rate Control in Patients With Atrial Fibrillation and Heart Failure With Preserved Ejection Fraction: Insights From Get With The Guidelines-Heart Failure.” J Am Heart Assoc 8, no. 24 (December 17, 2019): e011560. https://doi.org/10.1161/JAHA.118.011560.

PMID
31818219
Full Text

Fudim, Marat, Andrew R. Spector, Maria-Rosa Costanzo, Sean D. Pokorney, Robert J. Mentz, Dariusz Jagielski, Ralph Augostini, et al. “Phrenic Nerve Stimulation for the Treatment of Central Sleep Apnea: A Pooled Cohort Analysis.” J Clin Sleep Med 15, no. 12 (December 15, 2019): 1747–55. https://doi.org/10.5664/jcsm.8076.

PMID
31855160
Full Text

Pages