Pulmonary, Allergy, and Critical Care Medicine

Joseph Alan Govert, MD

Professor of Medicine
Campus mail 8 East, Room 42, Duke Medical Pavillion, Durham, NC 27710
Phone (919) 681-5919
Email address gover001@mc.duke.edu

I am trying to focus my research efforts in two specific areas, the medical intensive care unit, and clinical lung cancer research. Within the intensive care unit I am specifically interested in clinical trials and outcome evaluation. My interest in lung cancer centers on the clinical and cost effectiveness of various diagnostic procedures.

In the intensive care unit I am specifically involved in clinical trials for the adult respiratory distress syndrome (ARDS). At the present time I am on the steering committee for the NIH ARDS clinical trial network. We are currently enrolling patients in clinical protocols studying the effects of ventilator strategies, as well as novel therapeutic agents in the outcome of ARDS. I am also interested in ICU outcome research including statistical modeling of ICU outcomes.

My interest in lung cancer research centers on evaluating the efficacy of diagnostic tests in the diagnosis of pulmonary malignancy. I have retrospectively and prospectively evaluated brochoscopic procedures, comparing the sensitivity and specificity of various techniques as well as their cost-effectiveness. I am also currently analyzing the clinical utility and cost-effectiveness of positron emission tomography in the diagnosis of lung cancer.

Key words: clinical trials, medical intensive care, lung cancer diagnostic testing

Education and Training

  • Fellow in Pulmonary Medicine, Medicine, Duke University, 1993 - 1996
  • Resident, Medicine, Duke University, 1989 - 1992
  • M.D., University of California - Irvine, 1989

Grants

Publications

Grissom, Colin K., Eliotte L. Hirshberg, Justin B. Dickerson, Samuel M. Brown, Michael J. Lanspa, Kathleen D. Liu, David Schoenfeld, et al. “Fluid management with a simplified conservative protocol for the acute respiratory distress syndrome*.” Crit Care Med 43, no. 2 (February 2015): 288–95. https://doi.org/10.1097/CCM.0000000000000715.

PMID
25599463
Full Text

Schell-Chaple, Hildy M., Kathleen A. Puntillo, Michael A. Matthay, Kathleen D. Liu, and Kathleen D. National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome Network. “Body temperature and mortality in patients with acute respiratory distress syndrome.” Am J Crit Care 24, no. 1 (January 2015): 15–23. https://doi.org/10.4037/ajcc2015320.

PMID
25554550
Full Text

Catania, Jelena, Loretta G. Que, Joseph A. Govert, John W. Hollingsworth, and Cameron R. Wolfe. “High intensive care unit admission rate for 2013-2014 influenza is associated with a low rate of vaccination.” Am J Respir Crit Care Med 189, no. 4 (February 15, 2014): 485–87. https://doi.org/10.1164/rccm.201401-0066LE.

PMID
24512430
Full Text

Bae, Jonathan, Yvonne Acker, Joseph Govert, Jason Hester, Allen Kachalia, Thomas Owens, Wendy Snider, Shannon Rohan, and David Gallagher. “Implementation of a Hospital Medicine Morbidity and Mortality Conference and Mortality Review Using a Structured Mortality Instrument.,” 2013.

Scholars@Duke

Rosoff, Philip M., Kuldip R. Patel, Ann Scates, Gene Rhea, Paul W. Bush, and Joseph A. Govert. “Coping with critical drug shortages: an ethical approach for allocating scarce resources in hospitals.” Arch Intern Med 172, no. 19 (October 22, 2012): 1494–99. https://doi.org/10.1001/archinternmed.2012.4367.

PMID
23007382
Full Text

Turner, David A., Walter L. Williford, Michelle A. Peters, Janice J. Thalman, Ian R. Shearer, Richard J. Walczak, Michael Griffis, et al. “Development of a collaborative program to provide extracorporeal membrane oxygenation for adults with refractory hypoxemia within the framework of a pandemic.” Pediatr Crit Care Med 12, no. 4 (July 2011): 426–30. https://doi.org/10.1097/PCC.0b013e3181ff41c1.

PMID
21057349
Full Text

Norfolk, Stephanie G., Caroline L. Hollingsworth, Cameron R. Wolfe, Joseph A. Govert, Loretta G. Que, Ira M. Cheifetz, and John W. Hollingsworth. “Rescue therapy in adult and pediatric patients with pH1N1 influenza infection: a tertiary center intensive care unit experience from April to October 2009.” Crit Care Med 38, no. 11 (November 2010): 2103–7. https://doi.org/10.1097/CCM.0b013e3181f268f1.

PMID
20711068
Full Text

Unroe, Mark, Jeremy M. Kahn, Shannon S. Carson, Joseph A. Govert, Tereza Martinu, Shailaja J. Sathy, Alison S. Clay, et al. “One-year trajectories of care and resource utilization for recipients of prolonged mechanical ventilation: a cohort study.” Ann Intern Med 153, no. 3 (August 3, 2010): 167–75. https://doi.org/10.7326/0003-4819-153-3-201008030-00007.

PMID
20679561
Full Text

Ware, Lorraine B., Tatsuki Koyama, D Dean Billheimer, William Wu, Gordon R. Bernard, B Taylor Thompson, Roy G. Brower, et al. “Prognostic and pathogenetic value of combining clinical and biochemical indices in patients with acute lung injury.” Chest 137, no. 2 (February 2010): 288–96. https://doi.org/10.1378/chest.09-1484.

PMID
19858233
Full Text

Pages